GO Term : GO:0000398 mRNA splicing, via spliceosome GO

Namespace  biological_process Obsolete  false
description  The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.

0 Cross References

1 Ontology

Name
GO

24 Parents

Identifier Name Description
GO:0006396 RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016070 RNA metabolic process The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
GO:0006397 mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0000398 mRNA splicing, via spliceosome The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
GO:0006139 nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0008380 RNA splicing The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
GO:0006725 cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0090304 nucleic acid metabolic process Any cellular metabolic process involving nucleic acids.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0046483 heterocycle metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0034641 cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GO:1901360 organic cyclic compound metabolic process The chemical reactions and pathways involving organic cyclic compound.
GO:0010467 gene expression The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GO:0016071 mRNA metabolic process The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure.
GO:0000375 RNA splicing, via transesterification reactions Splicing of RNA via a series of two transesterification reactions.

29 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0030710.2 Quercus robur 98.1 egn (M=2) K12844 - U4/U6 small nuclear ribonucleoprotein PRP31     validated
Qrob_P0038890.2 Quercus robur 0.0 egn (M=3) K11095 - U1 small nuclear ribonucleoprotein C     validated
Qrob_P0112970.2 Quercus robur 55.4 egn (M=3) K11095 - U1 small nuclear ribonucleoprotein C     validated
Qrob_P0143650.2 Quercus robur 9.1 egn (M=4) K12874 - intron-binding protein aquarius     validated
Qrob_P0145250.2 Quercus robur 100.0 egn (M=1) KOG0119//KOG0122//KOG0124//KOG0144//KOG0145//KOG0148//KOG0149//KOG0307//KOG1588//KOG1984 - Splicing factor 1/branch point binding protein (RRM superfamily) [RNA processing and modification]. // Translation initiation factor 3 subunit g (eIF-3g) [Translation ribosomal structure and biogenesis]. // Polypyrimidine tract-binding protein PUF60 (RRM superfamily) [RNA processing and modification]. // RNA-binding protein CUGBP1/BRUNO (RRM superfamily) [RNA processing and modification]. // RNA-binding protein ELAV/HU (RRM superfamily) [RNA processing and modification]. // Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) [RNA processing and modification Translation ribosomal structure and biogenesis]. // Predicted RNA-binding protein SEB4 (RRM superfamily) [General function prediction only]. // Vesicle coat complex COPII subunit SEC31 [Intracellular trafficking secretion and vesicular transport]. // RNA-binding protein Sam68 and related KH domain proteins [RNA processing and modification]. // Vesicle coat complex COPII subunit SFB3 [Intracellular trafficking secretion and vesicular transport].     validated
Qrob_P0159570.2 Quercus robur 13.9 egn (M=2) K12844 - U4/U6 small nuclear ribonucleoprotein PRP31     validated
Qrob_P0181030.2 Quercus robur 12.0 egn (M=3) K11984 - U4/U6.U5 tri-snRNP-associated protein 1     validated
Qrob_P0211590.2 Quercus robur 99.0 egn (M=2) K12843 - U4/U6 small nuclear ribonucleoprotein PRP3     validated
Qrob_P0218910.2 Quercus robur 1.0 egn (M=4) K12874 - intron-binding protein aquarius     validated
Qrob_P0243110.2 Quercus robur 19.0 egn (M=2) K12843 - U4/U6 small nuclear ribonucleoprotein PRP3     validated
Qrob_P0244150.2 Quercus robur 91.0 egn (M=1) K11094 - U2 small nuclear ribonucleoprotein B''     validated
Qrob_P0261330.2 Quercus robur 10.2 egn (M=4) KOG2217 - U4/U6.U5 snRNP associated protein [RNA processing and modification].     validated
Qrob_P0341370.2 Quercus robur 0.0 egn (M=1) KOG1802//KOG1806 - RNA helicase nonsense mRNA reducing factor (pNORF1) [RNA processing and modification]. // DEAD box containing helicases [Replication recombination and repair].     validated
Qrob_P0341490.2 Quercus robur 0.0 egn (M=1) KOG1802//KOG1803//KOG1806//KOG1807 - RNA helicase nonsense mRNA reducing factor (pNORF1) [RNA processing and modification]. // DNA helicase [Replication recombination and repair]. // DEAD box containing helicases [Replication recombination and repair]. // Helicases [Replication recombination and repair].     validated
Qrob_P0348940.2 Quercus robur 69.2 egn (M=2) PTHR10501:SF0 - SMALL NUCLEAR RIBONUCLEOPROTEIN     validated
Qrob_P0362810.2 Quercus robur 100.0 egn (M=1) KOG0119//KOG0307//KOG0566//KOG1984 - Splicing factor 1/branch point binding protein (RRM superfamily) [RNA processing and modification]. // Vesicle coat complex COPII subunit SEC31 [Intracellular trafficking secretion and vesicular transport]. // Inositol-1 4 5-triphosphate 5-phosphatase (synaptojanin) INP51/INP52/INP53 family [Intracellular trafficking secretion and vesicular transport]. // Vesicle coat complex COPII subunit SFB3 [Intracellular trafficking secretion and vesicular transport].     validated
Qrob_P0371160.2 Quercus robur 100.0 egn (M=1) PTHR12794 - GEMIN2     validated
Qrob_P0379960.2 Quercus robur 0.0 egn (M=3) K06063 - SNW domain-containing protein 1     validated
Qrob_P0380030.2 Quercus robur 0.0 egn (M=3) K06063 - SNW domain-containing protein 1     validated
Qrob_P0446550.2 Quercus robur 35.2 egn (M=2) K12855 - pre-mRNA-processing factor 6     validated
Qrob_P0511570.2 Quercus robur 23.3 egn (M=4) K12874 - intron-binding protein aquarius     validated
Qrob_P0562770.2 Quercus robur 100.0 egn (M=1) K12856 - pre-mRNA-processing factor 8     validated
Qrob_P0565190.2 Quercus robur 0.0 egn (M=2) K12855 - pre-mRNA-processing factor 6     validated
Qrob_P0612730.2 Quercus robur 10.1 egn (M=1) KOG0117//KOG0119//KOG0122//KOG0123//KOG0124//KOG0127//KOG0144//KOG0145//KOG0148//KOG1588 - Heterogeneous nuclear ribonucleoprotein R (RRM superfamily) [RNA processing and modification]. // Splicing factor 1/branch point binding protein (RRM superfamily) [RNA processing and modification]. // Translation initiation factor 3 subunit g (eIF-3g) [Translation ribosomal structure and biogenesis]. // Polyadenylate-binding protein (RRM superfamily) [RNA processing and modification Translation ribosomal structure and biogenesis]. // Polypyrimidine tract-binding protein PUF60 (RRM superfamily) [RNA processing and modification]. // Nucleolar protein fibrillarin NOP77 (RRM superfamily) [RNA processing and modification]. // RNA-binding protein CUGBP1/BRUNO (RRM superfamily) [RNA processing and modification]. // RNA-binding protein ELAV/HU (RRM superfamily) [RNA processing and modification]. // Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) [RNA processing and modification Translation ribosomal structure and biogenesis]. // RNA-binding protein Sam68 and related KH domain proteins [RNA processing and modification].     validated
Qrob_P0685100.2 Quercus robur 97.0 egn (M=2) PTHR10501:SF0 - SMALL NUCLEAR RIBONUCLEOPROTEIN     validated
Qrob_P0702350.2 Quercus robur 94.3 egn (M=3) K11984 - U4/U6.U5 tri-snRNP-associated protein 1     validated
Qrob_P0706880.2 Quercus robur 100.0 egn (M=3) K06063 - SNW domain-containing protein 1     validated
Qrob_P0742610.2 Quercus robur 100.0 egn (M=1) KOG0147//KOG0151//KOG0334//KOG0415//KOG0670//KOG1874//KOG1999//KOG2217//KOG2888//KOG4676 - Transcriptional coactivator CAPER (RRM superfamily) [Transcription]. // Predicted splicing regulator contains RRM SWAP and RPR domains [General function prediction only]. // RNA helicase [RNA processing and modification]. // Predicted peptidyl prolyl cis-trans isomerase [Posttranslational modification protein turnover chaperones]. // U4/U6-associated splicing factor PRP4 [RNA processing and modification]. // KEKE-like motif-containing transcription regulator (Rlr1)/suppressor of sin4 [Transcription]. // RNA polymerase II transcription elongation factor DSIF/SUPT5H/SPT5 [Transcription]. // U4/U6.U5 snRNP associated protein [RNA processing and modification]. // Putative RNA binding protein [General function prediction only]. // Splicing factor arginine/serine-rich [RNA processing and modification].     validated
Qrob_P0743120.2 Quercus robur 100.0 egn (M=1) PTHR10548//PTHR10548:SF83 - SPLICING FACTOR, ARGININE/SERINE-RICH // SUBFAMILY NOT NAMED     validated

55 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0000398 GO:0000244
part of GO:0000398 GO:0000245
part of GO:0000398 GO:0000348
part of GO:0000398 GO:0000349
part of GO:0000398 GO:0000350
part of GO:0000398 GO:0000352
part of GO:0000398 GO:0000353
part of GO:0000398 GO:0000354
is_a GO:0000398 GO:0000365
is_a GO:0000398 GO:0000366
is_a GO:0000398 GO:0000380
regulates GO:0000398 GO:0000381
part of GO:0000398 GO:0000387
part of GO:0000398 GO:0000388
part of GO:0000398 GO:0000389
part of GO:0000398 GO:0000390
part of GO:0000398 GO:0000393
part of GO:0000398 GO:0000395
is_a GO:0000377 GO:0000398
is_a GO:0006397 GO:0000398
is_a GO:0006807 GO:0000398
is_a GO:0008152 GO:0000398
is_a GO:1901360 GO:0000398
is_a GO:0008150 GO:0000398
is_a GO:0000375 GO:0000398
is_a GO:0009987 GO:0000398
is_a GO:0006396 GO:0000398
part of GO:0071704 GO:0000398
is_a GO:0008380 GO:0000398
is_a GO:0006139 GO:0000398

9 Synonyms

Name Type
mRNA splicing synonym
nuclear mRNA splicing via U2-type spliceosome synonym
nuclear mRNA splicing via U12-type spliceosome synonym
pre-mRNA splicing synonym
nuclear mRNA splicing, via spliceosome synonym
splicing GT-AG intron synonym
splicing AT-AC intron synonym
GO:0006375 alt_id
GO:0006374 alt_id