GO Term : GO:0006281 DNA repair GO

Namespace  biological_process Obsolete  false
description  The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

0 Cross References

1 Ontology

Name
GO

25 Parents

Identifier Name Description
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0006281 DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0006139 nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0006259 DNA metabolic process Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
GO:0006974 cellular response to DNA damage stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0006725 cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0090304 nucleic acid metabolic process Any cellular metabolic process involving nucleic acids.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0046483 heterocycle metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0033554 cellular response to stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0034641 cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GO:1901360 organic cyclic compound metabolic process The chemical reactions and pathways involving organic cyclic compound.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.

97 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0008270.2 Quercus robur 100.0 egn (M=4) 3.2.2.20 - DNA-3-methyladenine glycosylase I.   EC:3.2.2.20 validated
Qrob_P0018830.2 Quercus robur 40.2 egn (M=1) PTHR11455//PTHR11455:SF12 - CRYPTOCHROME // SUBFAMILY NOT NAMED   EC:4.1.99.3 validated
Qrob_P0019500.2 Quercus robur 3.0 egn (M=1) PTHR13710//PTHR13710:SF75 - DNA HELICASE RECQ FAMILY MEMBER // SUBFAMILY NOT NAMED   EC:3.6.4.12 validated
Qrob_P0028440.2 Quercus robur 100.0 egn (M=2) K03511 - DNA polymerase kappa subunit [EC:2.7.7.7]   EC:2.7.7.7 validated
Qrob_P0028450.2 Quercus robur 99.0 egn (M=2) K03511 - DNA polymerase kappa subunit [EC:2.7.7.7]   EC:2.7.7.7 validated
Qrob_P0030200.2 Quercus robur 0.0 egn (M=3) K03512 - DNA polymerase lambda subunit [EC:2.7.7.7 4.2.99.-]   EC:2.7.7.7 validated
Qrob_P0038880.2 Quercus robur 0.0 egn (M=1) KOG0018//KOG0161//KOG0933//KOG0964//KOG0965//KOG0971//KOG0996//KOG1029 - Structural maintenance of chromosome protein 1 (sister chromatid cohesion complex Cohesin subunit SMC1) [Cell cycle control cell division chromosome partitioning]. // Myosin class II heavy chain [Cytoskeleton]. // Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin subunit E) [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning]. // Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin subunit SMC3) [Cell cycle control cell division chromosome partitioning]. // Predicted RNA-binding protein contains SWAP and G-patch domains [General function prediction only]. // Microtubule-associated protein dynactin DCTN1/Glued [Cell cycle control cell division chromosome partitioning Cytoskeleton]. // Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin subunit C) [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning]. // Endocytic adaptor protein intersectin [Signal transduction mechanisms Intracellular trafficking secretion and vesicular transport].     validated
Qrob_P0043960.2 Quercus robur 21.5 egn (M=1) K15255 - ATP-dependent DNA helicase PIF1 [EC:3.6.4.12]   EC:3.6.4.12 validated
Qrob_P0050330.2 Quercus robur 0.0 egn (M=2) PTHR23273//PTHR23273:SF0 - REPLICATION FACTOR A 1, RFA1 // SUBFAMILY NOT NAMED     validated
Qrob_P0063960.2 Quercus robur 97.0 egn (M=1) PTHR10799:SF558 - SNF2-RELATED DOMAIN-CONTAINING PROTEIN (PTHR10799:SF558)   EC:3.6.4.12 validated
Qrob_P0070910.2 Quercus robur 100.0 egn (M=4) 3.2.2.20 - DNA-3-methyladenine glycosylase I.   EC:3.2.2.20 validated
Qrob_P0074380.2 Quercus robur 100.0 egn (M=1) K10871 - RAD51-like protein 3   EC:3.6.1.8 validated
Qrob_P0078600.2 Quercus robur 99.1 egn (M=2) 6.5.1.1 - DNA ligase (ATP).   EC:6.5.1.1 validated
Qrob_P0082320.2 Quercus robur 76.0 egn (M=1) K11324 - DNA methyltransferase 1-associated protein 1     validated
Qrob_P0082880.2 Quercus robur 60.1 egn (M=1) PTHR18867 - RAD50   EC:3.6.3.25 validated
Qrob_P0088630.2 Quercus robur 97.2 egn (M=3) 3.2.2.27 - Uracil-DNA glycosylase.   EC:3.2.2.27 validated
Qrob_P0102800.2 Quercus robur 0.0 egn (M=1) K10879 - DNA-repair protein XRCC2     validated
Qrob_P0102820.2 Quercus robur 0.0 egn (M=2) K03648 - uracil-DNA glycosylase [EC:3.2.2.-]   EC:3.2.2.27 validated
Qrob_P0102830.2 Quercus robur 100.0 egn (M=2) K03648 - uracil-DNA glycosylase [EC:3.2.2.-]   EC:3.2.2.27 validated
Qrob_P0112640.2 Quercus robur 93.1 egn (M=1) 3.1.11.2 - Exodeoxyribonuclease III.   EC:3.1.11.2 validated
Qrob_P0135310.2 Quercus robur 83.4 egn (M=1) K10740 - replication factor A3     validated
Qrob_P0139950.2 Quercus robur 92.0 egn (M=2) 3.1.16.1 - Spleen exonuclease.   EC:3.1.16.1 validated
Qrob_P0144170.2 Quercus robur 42.0 egn (M=2) PTHR10670 - DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A   EC:2.7.7.7 validated
Qrob_P0146560.2 Quercus robur 96.0 egn (M=1) KOG0250//KOG0979 - DNA repair protein RAD18 (SMC family protein) [Replication recombination and repair]. // Structural maintenance of chromosome protein SMC5/Spr18 SMC superfamily [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning Replication recombination and repair].     validated
Qrob_P0146570.2 Quercus robur 91.0 egn (M=1) KOG0161//KOG0250//KOG0933//KOG0964//KOG0979//KOG0996 - Myosin class II heavy chain [Cytoskeleton]. // DNA repair protein RAD18 (SMC family protein) [Replication recombination and repair]. // Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin subunit E) [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning]. // Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin subunit SMC3) [Cell cycle control cell division chromosome partitioning]. // Structural maintenance of chromosome protein SMC5/Spr18 SMC superfamily [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning Replication recombination and repair]. // Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin subunit C) [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning].     validated
Qrob_P0149640.2 Quercus robur 99.0 egn (M=1) K10683 - BRCA1-associated RING domain protein 1 [EC:6.3.2.19]   EC:6.3.2.19 validated
Qrob_P0151060.2 Quercus robur 100.0 egn (M=1) K15360 - centromere protein X     validated
Qrob_P0152360.2 Quercus robur 100.0 egn (M=1) PTHR12172 - CELL CYCLE CHECKPOINT PROTEIN RAD17     validated
Qrob_P0155250.2 Quercus robur 43.6 egn (M=2) PF00154//PF00560//PF00931 - recA bacterial DNA recombination protein // Leucine Rich Repeat // NB-ARC domain     validated
Qrob_P0171260.2 Quercus robur 19.0 egn (M=1) PTHR13710:SF72 - ATP-DEPENDENT DNA HELICASE Q1 (PTHR13710:SF72)   EC:3.6.4.12 validated

171 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0006281 GO:0000012
part of GO:0006281 GO:0000706
part of GO:0006281 GO:0000707
is_a GO:0006281 GO:0000710
part of GO:0006281 GO:0000711
part of GO:0006281 GO:0000715
part of GO:0006281 GO:0000716
part of GO:0006281 GO:0000717
part of GO:0006281 GO:0000718
is_a GO:0006281 GO:0000719
is_a GO:0006281 GO:0000720
is_a GO:0006281 GO:0000724
is_a GO:0006281 GO:0000725
is_a GO:0006281 GO:0000726
is_a GO:0006281 GO:0000727
part of GO:0006281 GO:0000729
part of GO:0006281 GO:0000730
part of GO:0006281 GO:0000731
part of GO:0006281 GO:0000734
part of GO:0006281 GO:0000736
is_a GO:0006974 GO:0006281
is_a GO:0006259 GO:0006281
is_a GO:0044763 GO:0006281
is_a GO:0044710 GO:0006281
is_a GO:0044260 GO:0006281
is_a GO:0046483 GO:0006281
is_a GO:0006139 GO:0006281
is_a GO:0008150 GO:0006281
is_a GO:0008152 GO:0006281
is_a GO:0034641 GO:0006281

0 Synonyms