Protein : Qrob_P0171260.2 Q. robur

Protein Identifier  ? Qrob_P0171260.2 Organism . Name  Quercus robur
Score  19.0 Score Type  egn
Protein Description  (M=1) PTHR13710:SF72 - ATP-DEPENDENT DNA HELICASE Q1 (PTHR13710:SF72) Code Enzyme  EC:3.6.4.12
Gene Prediction Quality  validated Protein length 

Sequence

Length: 346  
Kegg Orthology  K10899

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0 Synonyms

5 GO Terms

Identifier Name Description
GO:0003676 nucleic acid binding Interacting selectively and non-covalently with any nucleic acid.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0006281 DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
GO:0006260 DNA replication The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
GO:0043140 ATP-dependent 3'-5' DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 3' to 5'.

34 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pmum:103336719 1 345 + 345 Gaps:31 44.48 706 78.34 2e-168 mediator of RNA polymerase II transcription subunit 34
blastp_kegg lcl|pper:PRUPE_ppa026000mg 7 345 + 339 Gaps:31 100.00 308 77.60 9e-168 hypothetical protein
blastp_kegg lcl|pxb:103935168 1 345 + 345 Gaps:32 44.40 705 75.72 3e-167 mediator of RNA polymerase II transcription subunit 34
blastp_kegg lcl|cam:101503147 1 345 + 345 Gaps:36 43.89 704 76.70 3e-158 mediator of RNA polymerase II transcription subunit 34-like
blastp_kegg lcl|vvi:100256266 1 345 + 345 Gaps:29 44.73 711 74.84 2e-157 ATP-dependent DNA helicase Q-like 2-like
blastp_kegg lcl|fve:101300545 1 303 + 303 Gaps:7 41.81 708 76.01 2e-157 mediator of RNA polymerase II transcription subunit 34-like
blastp_kegg lcl|mtr:MTR_5g026590 1 345 + 345 Gaps:36 45.11 685 75.73 2e-155 ATP-dependent DNA helicase RecQ family protein expressed
blastp_kegg lcl|pvu:PHAVU_002G126800g 1 344 + 344 Gaps:35 44.02 702 74.76 1e-154 hypothetical protein
blastp_kegg lcl|rcu:RCOM_0865580 1 344 + 344 Gaps:30 43.98 714 74.20 2e-153 DNA helicase recq1 putative
blastp_kegg lcl|gmx:100817635 1 339 + 339 Gaps:35 43.74 695 73.36 3e-147 mediator of RNA polymerase II transcription subunit 34-like
blastp_pdb 2wwy_B 1 201 + 201 Gaps:9 35.53 591 34.29 5e-37 mol:protein length:591 ATP-DEPENDENT DNA HELICASE Q1
blastp_pdb 2wwy_A 1 201 + 201 Gaps:9 35.53 591 34.29 5e-37 mol:protein length:591 ATP-DEPENDENT DNA HELICASE Q1
blastp_pdb 2v1x_B 1 201 + 201 Gaps:9 35.53 591 34.29 5e-37 mol:protein length:591 ATP-DEPENDENT DNA HELICASE Q1
blastp_pdb 2v1x_A 1 201 + 201 Gaps:9 35.53 591 34.29 5e-37 mol:protein length:591 ATP-DEPENDENT DNA HELICASE Q1
blastp_pdb 1oyy_A 1 188 + 188 Gaps:37 37.67 523 29.95 6e-11 mol:protein length:523 ATP-dependent DNA helicase
blastp_pdb 1oyw_A 1 188 + 188 Gaps:37 37.67 523 29.95 6e-11 mol:protein length:523 ATP-dependent DNA helicase
blastp_uniprot_sprot sp|Q9FT73|MED34_ARATH 1 344 + 344 Gaps:34 43.97 705 66.77 3e-133 Mediator of RNA polymerase II transcription subunit 34 OS Arabidopsis thaliana GN MED34 PE 1 SV 1
blastp_uniprot_sprot sp|P46063|RECQ1_HUMAN 1 201 + 201 Gaps:9 32.36 649 34.29 1e-36 ATP-dependent DNA helicase Q1 OS Homo sapiens GN RECQL PE 1 SV 3
blastp_uniprot_sprot sp|Q5RF63|RECQ1_PONAB 1 194 + 194 Gaps:9 31.28 649 34.98 2e-36 ATP-dependent DNA helicase Q1 OS Pongo abelii GN RECQL PE 2 SV 1
blastp_uniprot_sprot sp|Q6AYJ1|RECQ1_RAT 1 173 + 173 Gaps:9 29.31 621 39.56 2e-35 ATP-dependent DNA helicase Q1 OS Rattus norvegicus GN Recql PE 2 SV 1
blastp_uniprot_sprot sp|Q9Z129|RECQ1_MOUSE 1 173 + 173 Gaps:9 28.09 648 39.01 2e-33 ATP-dependent DNA helicase Q1 OS Mus musculus GN Recql PE 1 SV 2
blastp_uniprot_sprot sp|Q9TXJ8|RECQ1_CAEEL 1 210 + 210 Gaps:22 33.60 631 36.79 6e-32 Putative ATP-dependent DNA helicase Q1 OS Caenorhabditis elegans GN K02F3.12 PE 3 SV 3
blastp_uniprot_sprot sp|P54132|BLM_HUMAN 1 290 + 290 Gaps:58 22.87 1417 32.10 7e-25 Bloom syndrome protein OS Homo sapiens GN BLM PE 1 SV 1
blastp_uniprot_sprot sp|O88700|BLM_MOUSE 1 290 + 290 Gaps:51 22.67 1416 31.46 6e-24 Bloom syndrome protein homolog OS Mus musculus GN Blm PE 1 SV 1
blastp_uniprot_sprot sp|Q9I920|BLM_CHICK 1 328 + 328 Gaps:62 32.22 1142 29.35 2e-23 Bloom syndrome protein homolog (Fragment) OS Gallus gallus GN BLM PE 2 SV 1
blastp_uniprot_sprot sp|Q9DEY9|BLM_XENLA 1 314 + 314 Gaps:58 25.51 1364 29.31 5e-23 Bloom syndrome protein homolog OS Xenopus laevis GN blm PE 2 SV 1
rpsblast_cdd gnl|CDD|130456 1 282 + 282 Gaps:37 48.56 591 28.22 1e-21 TIGR01389 recQ ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions as well as more distantly related bacterial helicases related to RecQ.
rpsblast_cdd gnl|CDD|30860 1 285 + 285 Gaps:47 47.46 590 27.14 3e-20 COG0514 RecQ Superfamily II DNA helicase [DNA replication recombination and repair].
rpsblast_cdd gnl|CDD|129701 1 121 + 121 Gaps:22 29.15 470 37.96 1e-18 TIGR00614 recQ_fam ATP-dependent DNA helicase RecQ family. All proteins in this family for which functions are known are 3'-5' DNA-DNA helicases. These proteins are used for recombination recombinational repair and possibly maintenance of chromosome stability. This family is based on the phylogenomic analysis of JA Eisen (1999 Ph.D. Thesis Stanford University).
rpsblast_cdd gnl|CDD|178682 1 306 + 306 Gaps:71 30.54 1195 25.21 2e-15 PLN03137 PLN03137 ATP-dependent DNA helicase Q4-like Provisional.

11 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Coils 249 270 22 Coil none none none
Pfam 92 186 95 PF09382 none RQC domain IPR018982
SUPERFAMILY 1 124 124 SSF52540 none none IPR027417
Coils 120 141 22 Coil none none none
Pfam 212 278 67 PF00570 none HRDC domain IPR002121
PANTHER 1 289 289 PTHR13710:SF72 none none none
PANTHER 1 289 289 PTHR13710 none none none
Gene3D 39 189 151 G3DSA:1.10.10.10 none none IPR011991
SMART 92 189 98 SM00956 none none IPR018982
Gene3D 1 31 31 G3DSA:3.40.50.300 none none IPR027417
ProSiteProfiles 203 289 87 PS50967 none HRDC domain profile. IPR002121

0 Localization

0 Qtllist

0 Targeting