Protein : Qrob_P0146570.2 Q. robur
Protein Identifier  ? Qrob_P0146570.2 Organism . Name  Quercus robur
Score  91.0 Score Type  egn
Protein Description  (M=1) KOG0161//KOG0250//KOG0933//KOG0964//KOG0979//KOG0996 - Myosin class II heavy chain [Cytoskeleton]. // DNA repair protein RAD18 (SMC family protein) [Replication recombination and repair]. // Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin subunit E) [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning]. // Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin subunit SMC3) [Cell cycle control cell division chromosome partitioning]. // Structural maintenance of chromosome protein SMC5/Spr18 SMC superfamily [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning Replication recombination and repair]. // Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin subunit C) [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning]. Gene Prediction Quality  validated
Protein length 

Sequence

Length: 937  
Paste the following link
Lists
This Protein isn't in any lists. Upload a list.

Sequence Feature Displayer

Protein Sequence Displayer

J Browse Displayer

0 Synonyms

7 GO Terms

Identifier Name Description
GO:0005515 protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO:0005524 ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0006281 DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
GO:0005694 chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
GO:0051276 chromosome organization A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.
GO:0000724 double-strand break repair via homologous recombination The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
GO:0030915 Smc5-Smc6 complex A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans.

35 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|vvi:100249449 9 932 + 924 Gaps:35 84.11 1057 73.34 0.0 structural maintenance of chromosomes protein 6-like
blastp_kegg lcl|cmo:103494485 9 932 + 924 Gaps:34 79.96 1113 73.37 0.0 structural maintenance of chromosomes protein 6B-like
blastp_kegg lcl|csv:101208493 9 932 + 924 Gaps:34 84.60 1052 73.15 0.0 structural maintenance of chromosomes protein 6-like
blastp_kegg lcl|cit:102612928 9 932 + 924 Gaps:34 84.12 1058 71.24 0.0 structural maintenance of chromosomes protein 6B-like
blastp_kegg lcl|rcu:RCOM_1500700 9 932 + 924 Gaps:34 84.12 1058 69.66 0.0 structural maintenance of chromosomes 6 smc6 putative
blastp_kegg lcl|pmum:103333367 9 932 + 924 Gaps:34 84.52 1053 70.90 0.0 structural maintenance of chromosomes protein 6B
blastp_kegg lcl|mdm:103439624 9 932 + 924 Gaps:36 84.49 1051 69.26 0.0 structural maintenance of chromosomes protein 6B-like
blastp_kegg lcl|pxb:103961941 9 932 + 924 Gaps:43 84.59 1058 68.94 0.0 structural maintenance of chromosomes protein 6B-like
blastp_kegg lcl|pxb:103959810 9 932 + 924 Gaps:50 84.69 1065 68.63 0.0 structural maintenance of chromosomes protein 6B-like
blastp_kegg lcl|pop:POPTR_0003s10690g 9 932 + 924 Gaps:49 83.84 1046 68.99 0.0 POPTRDRAFT_830778 hypothetical protein
blastp_uniprot_sprot sp|Q9FII7|SMC6B_ARATH 9 932 + 924 Gaps:35 84.11 1057 62.32 0.0 Structural maintenance of chromosomes protein 6B OS Arabidopsis thaliana GN SMC6B PE 2 SV 1
blastp_uniprot_sprot sp|Q9FLR5|SMC6A_ARATH 9 932 + 924 Gaps:35 84.03 1058 60.07 0.0 Structural maintenance of chromosomes protein 6A OS Arabidopsis thaliana GN SMC6A PE 2 SV 1
blastp_uniprot_sprot sp|Q96SB8|SMC6_HUMAN 6 932 + 927 Gaps:110 80.57 1091 27.42 2e-59 Structural maintenance of chromosomes protein 6 OS Homo sapiens GN SMC6 PE 1 SV 2
blastp_uniprot_sprot sp|Q6P9I7|SMC6_XENLA 6 932 + 927 Gaps:107 77.84 1128 26.08 2e-56 Structural maintenance of chromosomes protein 6 OS Xenopus laevis GN smc6 PE 2 SV 1
blastp_uniprot_sprot sp|Q924W5|SMC6_MOUSE 6 932 + 927 Gaps:102 80.13 1097 27.19 1e-54 Structural maintenance of chromosomes protein 6 OS Mus musculus GN Smc6 PE 2 SV 1
blastp_uniprot_sprot sp|Q802R8|SMC6_TAKRU 9 932 + 924 Gaps:87 80.28 1090 25.26 6e-51 Structural maintenance of chromosomes protein 6 OS Takifugu rubripes GN smc6 PE 2 SV 1
blastp_uniprot_sprot sp|Q54I56|SMC6_DICDI 4 929 + 926 Gaps:131 74.35 1185 26.22 4e-43 Structural maintenance of chromosomes protein 6 OS Dictyostelium discoideum GN smc6 PE 3 SV 1
blastp_uniprot_sprot sp|P53692|SMC6_SCHPO 8 932 + 925 Gaps:149 77.54 1140 25.68 2e-41 Structural maintenance of chromosomes protein 6 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN smc6 PE 1 SV 1
blastp_uniprot_sprot sp|Q12749|SMC6_YEAST 9 932 + 924 Gaps:164 78.55 1114 27.20 1e-31 Structural maintenance of chromosomes protein 6 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN SMC6 PE 1 SV 1
blastp_uniprot_sprot sp|Q08204|SMC5_YEAST 819 929 + 111 Gaps:6 10.52 1093 34.78 1e-09 Structural maintenance of chromosomes protein 5 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN SMC5 PE 1 SV 1
rpsblast_cdd gnl|CDD|73035 855 932 + 78 Gaps:1 39.90 198 58.23 1e-28 cd03276 ABC_SMC6_euk Eukaryotic SMC6 proteins SMC proteins are large (approximately 110 to 170 kDa) and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T in the single-letter amino-acid code) which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells the proteins are found as heterodimers of SMC1 paired with SMC3 SMC2 with SMC4 and SMC5 with SMC6 (formerly known as Rad18)..
rpsblast_cdd gnl|CDD|31389 23 932 + 910 Gaps:166 79.19 1163 31.49 6e-23 COG1196 Smc Chromosome segregation ATPases [Cell division and chromosome partitioning].
rpsblast_cdd gnl|CDD|162740 47 904 + 858 Gaps:148 73.88 1164 20.00 2e-19 TIGR02169 SMC_prok_A chromosome segregation protein SMC primarily archaeal type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria archaea and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes but six paralogs (excluded from this family) are found in eukarotes where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex Synechocystis etc) the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved but the central hinge region is skewed in composition and highly divergent.
rpsblast_cdd gnl|CDD|162739 44 803 + 760 Gaps:140 67.43 1179 23.14 5e-19 TIGR02168 SMC_prok_B chromosome segregation protein SMC common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria archaea and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle.
rpsblast_cdd gnl|CDD|72998 867 929 + 63 Gaps:1 34.83 178 40.32 1e-11 cd03239 ABC_SMC_head The structural maintenance of chromosomes (SMC) proteins are essential for successful chromosome transmission during replication and segregation of the genome in all organisms. SMCs are generally present as single proteins in bacteria and as at least six distinct proteins in eukaryotes. The proteins range in size from approximately 110 to 170 kDa and each has five distinct domains: amino- and carboxy-terminal globular domains which contain sequences characteristic of ATPases two coiled-coil regions separating the terminal domains and a central flexible hinge. SMC proteins function together with other proteins in a range of chromosomal transactions including chromosome condensation sister-chromatid cohesion recombination DNA repair and epigenetic silencing of gene expression..
rpsblast_cdd gnl|CDD|73036 868 934 + 67 Gaps:4 33.33 213 45.07 9e-10 cd03277 ABC_SMC5_euk Eukaryotic SMC5 proteins SMC proteins are large (approximately 110 to 170 kDa) and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T in the single-letter amino-acid code) which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells the proteins are found as heterodimers of SMC1 paired with SMC3 SMC2 with SMC4 and SMC5 with SMC6 (formerly known as Rad18)..
rpsblast_cdd gnl|CDD|202246 48 908 + 861 Gaps:83 76.94 1162 14.21 2e-09 pfam02463 SMC_N RecF/RecN/SMC N terminal domain. This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
rpsblast_cdd gnl|CDD|30768 534 931 + 398 Gaps:21 45.04 908 17.60 2e-07 COG0419 SbcC ATPase involved in DNA repair [DNA replication recombination and repair].
rpsblast_cdd gnl|CDD|72986 866 929 + 64 Gaps:1 38.89 162 33.33 6e-07 cd03227 ABC_Class2 ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterised by the fact that the ABC subunit is made up of duplicated fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins..
rpsblast_kog gnl|CDD|35471 11 932 + 922 Gaps:53 82.22 1074 35.56 0.0 KOG0250 KOG0250 KOG0250 DNA repair protein RAD18 (SMC family protein) [Replication recombination and repair].

26 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Coils 310 338 29 Coil none none none
Phobius 267 936 670 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
SUPERFAMILY 697 747 51 SSF52540 none none IPR027417
SUPERFAMILY 6 87 82 SSF52540 none none IPR027417
SUPERFAMILY 852 928 77 SSF52540 none none IPR027417
Coils 753 795 43 Coil none none none
Phobius 1 241 241 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Coils 177 198 22 Coil none none none
Coils 149 170 22 Coil none none none
Gene3D 53 85 33 G3DSA:1.20.1480.30 none none none
Gene3D 6 52 47 G3DSA:3.40.50.300 none none IPR027417
Gene3D 824 931 108 G3DSA:3.40.50.300 none none IPR027417
PANTHER 264 932 669 PTHR19306:SF2 none none IPR027132
PANTHER 10 229 220 PTHR19306:SF2 none none IPR027132
Phobius 242 266 25 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
SUPERFAMILY 323 510 188 SSF75553 none none IPR010935
Coils 534 583 50 Coil none none none
Coils 694 722 29 Coil none none none
Coils 205 226 22 Coil none none none
Coils 54 89 36 Coil none none none
Coils 609 658 50 Coil none none none
SUPERFAMILY 838 928 91 SSF52540 none none IPR027417
Coils 275 296 22 Coil none none none
PANTHER 264 932 669 PTHR19306 none none none
PANTHER 10 229 220 PTHR19306 none none none
Coils 665 686 22 Coil none none none

1 Localization

Analysis Start End Length
TMHMM 243 265 22

6 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nLBD*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 34,91 16,12 53,62 lod 2,4961 5,2
Bourran2_2014_rEpiBC*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 35,77 14,11 55,31 lod 2,9413 6,2
Bourran_2000_2002_QTL6_Delta.F Qrob_Chr03 3 s_2HYXJ2_207 s_1AUAXK_317 29.12 6,3 45,37 lod 3.1666 0.026
Bourran2_2014_nLBD_3P Qrob_Chr03 3 s_1ET7H8_604 s_1BYNB5_834 23,73 0 46,72 lod 1,7573 3,8
PM_1999_QTL14_peak_Bud_burst_3P Qrob_Chr03 3 s_2F0SI1_756 v_6056_735 11,78 3,78 50,78 lod 2,5 4,5
Bourran2_2014_rEpiBC*_3P Qrob_Chr03 3 s_1A3B3X_1163 s_1DKGMO_450 23,04 4,92 41,12 lod 2,5668 7

0 Targeting