GO Term : GO:0030915 Smc5-Smc6 complex GO

Namespace  cellular_component Obsolete  false
description  A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans.

0 Cross References

1 Ontology

Name
GO

17 Parents

Identifier Name Description
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005694 chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:0030915 Smc5-Smc6 complex A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans.
GO:0044424 intracellular part Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0044422 organelle part Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
GO:0044446 intracellular organelle part A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
GO:0043226 organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GO:0043229 intracellular organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0043228 non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
GO:0043232 intracellular non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
GO:0044427 chromosomal part Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
GO:0000793 condensed chromosome A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.

7 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0146560.2 Quercus robur 96.0 egn (M=1) KOG0250//KOG0979 - DNA repair protein RAD18 (SMC family protein) [Replication recombination and repair]. // Structural maintenance of chromosome protein SMC5/Spr18 SMC superfamily [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning Replication recombination and repair].     validated
Qrob_P0146570.2 Quercus robur 91.0 egn (M=1) KOG0161//KOG0250//KOG0933//KOG0964//KOG0979//KOG0996 - Myosin class II heavy chain [Cytoskeleton]. // DNA repair protein RAD18 (SMC family protein) [Replication recombination and repair]. // Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin subunit E) [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning]. // Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin subunit SMC3) [Cell cycle control cell division chromosome partitioning]. // Structural maintenance of chromosome protein SMC5/Spr18 SMC superfamily [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning Replication recombination and repair]. // Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin subunit C) [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning].     validated
Qrob_P0300490.2 Quercus robur 100.0 egn (M=2) PTHR20973 - NON-SMC ELEMENT 1-RELATED     validated
Qrob_P0300500.2 Quercus robur 100.0 egn (M=2) PTHR20973 - NON-SMC ELEMENT 1-RELATED     validated
Qrob_P0358620.2 Quercus robur 100.0 egn (M=2) KOG2866 - Uncharacterized conserved protein [Function unknown].     validated
Qrob_P0595290.2 Quercus robur 94.1 egn (M=1) PTHR19306:SF1 - STRUCTURAL MAINTENANCE OF CHROMOSOMES 5 SMC5     validated
Qrob_P0667160.2 Quercus robur 100.0 egn (M=2) KOG2866 - Uncharacterized conserved protein [Function unknown].     validated

19 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0043234 GO:0030915
is_a GO:0044427 GO:0030915
part of GO:0000793 GO:0030915
is_a GO:0044446 GO:0030915
is_a GO:0005575 GO:0030915
is_a GO:0032991 GO:0030915
is_a GO:0044424 GO:0030915
is_a GO:0044422 GO:0030915
part of GO:0044464 GO:0030915
part of GO:0043229 GO:0030915
part of GO:0043228 GO:0030915
part of GO:0005694 GO:0030915
part of GO:0005623 GO:0030915
part of GO:0005622 GO:0030915
part of GO:0005575 GO:0030915
is_a GO:0044464 GO:0030915
part of GO:0043232 GO:0030915
part of GO:0043226 GO:0030915
part of GO:0044424 GO:0030915

0 Synonyms