Protein : Qrob_P0038880.2 Q. robur

Protein Identifier  ? Qrob_P0038880.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=1) KOG0018//KOG0161//KOG0933//KOG0964//KOG0965//KOG0971//KOG0996//KOG1029 - Structural maintenance of chromosome protein 1 (sister chromatid cohesion complex Cohesin subunit SMC1) [Cell cycle control cell division chromosome partitioning]. // Myosin class II heavy chain [Cytoskeleton]. // Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin subunit E) [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning]. // Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin subunit SMC3) [Cell cycle control cell division chromosome partitioning]. // Predicted RNA-binding protein contains SWAP and G-patch domains [General function prediction only]. // Microtubule-associated protein dynactin DCTN1/Glued [Cell cycle control cell division chromosome partitioning Cytoskeleton]. // Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin subunit C) [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning]. // Endocytic adaptor protein intersectin [Signal transduction mechanisms Intracellular trafficking secretion and vesicular transport]. Gene Prediction Quality  validated
Protein length 

Sequence

Length: 649  

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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0006281 DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
GO:0000014 single-stranded DNA endodeoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks.
GO:0000077 DNA damage checkpoint A cell cycle checkpoint that regulates progression through the cell cycle in response to DNA damage. A DNA damage checkpoint may blocks cell cycle progression (in G1, G2 or metaphase) or slow the rate at which S phase proceeds.

31 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|cit:102625466 1 647 + 647 Gaps:12 100.00 647 59.20 0.0 protein gamma response 1-like
blastp_kegg lcl|tcc:TCM_005912 1 647 + 647 Gaps:27 100.00 656 57.93 0.0 Gamma response gene 1 putative isoform 1
blastp_kegg lcl|vvi:100855359 1 647 + 647 Gaps:21 100.00 640 58.44 0.0 protein gamma response 1-like
blastp_kegg lcl|cic:CICLE_v10030953mg 1 629 + 629 Gaps:12 100.00 629 58.03 0.0 hypothetical protein
blastp_kegg lcl|pop:POPTR_0009s06870g 15 647 + 633 Gaps:22 98.28 640 57.39 0.0 POPTRDRAFT_722745 hypothetical protein
blastp_kegg lcl|cmo:103499908 11 647 + 637 Gaps:17 98.34 661 53.85 0.0 protein gamma response 1
blastp_kegg lcl|csv:101209666 1 647 + 647 Gaps:18 100.00 661 53.10 0.0 protein gamma response 1-like
blastp_kegg lcl|pxb:103945848 14 647 + 634 Gaps:53 98.53 614 59.83 0.0 protein gamma response 1-like
blastp_kegg lcl|rcu:RCOM_1525380 5 647 + 643 Gaps:27 99.05 632 57.99 0.0 retinoblastoma binding protein putative
blastp_kegg lcl|pop:POPTR_0001s27650g 1 647 + 647 Gaps:34 100.00 629 56.92 0.0 POPTRDRAFT_549340 GAMMA RESPONSE 1 family protein
blastp_uniprot_sprot sp|Q9ZRT1|GR1_ARATH 15 647 + 633 Gaps:64 99.15 588 47.00 7e-137 Protein gamma response 1 OS Arabidopsis thaliana GN GR1 PE 1 SV 2
blastp_uniprot_sprot sp|F1R983|COM1_DANRE 566 645 + 80 Gaps:12 10.45 651 54.41 5e-11 DNA endonuclease RBBP8 OS Danio rerio GN rbbp8 PE 2 SV 1
blastp_uniprot_sprot sp|F6SNN2|COM1_XENTR 567 645 + 79 Gaps:12 7.73 867 49.25 3e-10 DNA endonuclease RBBP8 OS Xenopus tropicalis GN rbbp8 PE 3 SV 1
blastp_uniprot_sprot sp|Q6GNV6|COM1_XENLA 567 645 + 79 Gaps:12 7.83 856 47.76 5e-10 DNA endonuclease RBBP8 OS Xenopus laevis GN rbbp8 PE 1 SV 1
blastp_uniprot_sprot sp|Q80YR6|COM1_MOUSE 566 645 + 80 Gaps:12 7.61 893 48.53 1e-09 DNA endonuclease RBBP8 OS Mus musculus GN Rbbp8 PE 1 SV 1
blastp_uniprot_sprot sp|Q99708|COM1_HUMAN 566 645 + 80 Gaps:12 7.58 897 47.06 2e-09 DNA endonuclease RBBP8 OS Homo sapiens GN RBBP8 PE 1 SV 2
blastp_uniprot_sprot sp|B1WC58|COM1_RAT 566 645 + 80 Gaps:12 7.61 893 47.06 2e-08 DNA endonuclease RBBP8 OS Rattus norvegicus GN Rbbp8 PE 2 SV 1
rpsblast_cdd gnl|CDD|192074 569 645 + 77 Gaps:16 100.00 93 31.18 4e-15 pfam08573 SAE2 DNA repair protein endonuclease SAE2/CtIP C-terminus. SAE2 is a protein involved in repairing meiotic and mitotic double-strand breaks in DNA. It has been shown to negatively regulate DNA damage checkpoint signalling. SAE2 is homologous to the CtIP proteins in mammals and an homologous protein in plants. Crucial sequence motifs that are highly conserved are the CxxC and the RHR motifs in this C-terminal part of the protein. It is now known to be an endonuclease. In budding yeast genetic evidence suggests that the SAE2 protein is essential for the processing of hairpin DNA intermediates and meiotic double-strand breaks by Mre11/Rad50 complexes. SAE2 binds DNA and exhibits endonuclease activity on single-stranded DNA independently of Mre11/Rad50 complexes but hairpin DNA structures are cleaved cooperatively in the presence of Mre11/Rad50 or Mre11/Rad50/Xrs2. Hairpin structures are not processed at the tip by SAE2 but rather at single-stranded DNA regions adjacent to the hairpin. The catalytic activities of SAE2 are important for its biological functions.
rpsblast_cdd gnl|CDD|31389 69 385 + 317 Gaps:39 52.62 1163 28.76 2e-13 COG1196 Smc Chromosome segregation ATPases [Cell division and chromosome partitioning].
rpsblast_cdd gnl|CDD|162739 69 375 + 307 Gaps:112 48.94 1179 39.34 3e-11 TIGR02168 SMC_prok_B chromosome segregation protein SMC common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria archaea and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle.
rpsblast_cdd gnl|CDD|179675 50 379 + 330 Gaps:64 43.18 880 28.42 4e-10 PRK03918 PRK03918 chromosome segregation protein Provisional.
rpsblast_cdd gnl|CDD|162740 79 386 + 308 Gaps:60 48.80 1164 31.69 4e-10 TIGR02169 SMC_prok_A chromosome segregation protein SMC primarily archaeal type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria archaea and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes but six paralogs (excluded from this family) are found in eukarotes where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex Synechocystis etc) the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved but the central hinge region is skewed in composition and highly divergent.
rpsblast_cdd gnl|CDD|30768 72 374 + 303 Gaps:17 31.50 908 18.88 8e-07 COG0419 SbcC ATPase involved in DNA repair [DNA replication recombination and repair].
rpsblast_kog gnl|CDD|36183 102 646 + 545 Gaps:50 50.30 988 9.46 2e-38 KOG0965 KOG0965 KOG0965 Predicted RNA-binding protein contains SWAP and G-patch domains [General function prediction only].
rpsblast_kog gnl|CDD|35383 34 410 + 377 Gaps:164 47.20 1930 40.40 2e-18 KOG0161 KOG0161 KOG0161 Myosin class II heavy chain [Cytoskeleton].
rpsblast_kog gnl|CDD|36151 73 368 + 296 Gaps:33 29.30 1174 27.62 9e-10 KOG0933 KOG0933 KOG0933 Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin subunit E) [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning].
rpsblast_kog gnl|CDD|36214 69 384 + 316 Gaps:68 54.91 1293 28.87 3e-08 KOG0996 KOG0996 KOG0996 Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin subunit C) [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning].
rpsblast_kog gnl|CDD|36182 95 386 + 292 Gaps:18 24.00 1200 19.79 2e-07 KOG0964 KOG0964 KOG0964 Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin subunit SMC3) [Cell cycle control cell division chromosome partitioning].
rpsblast_kog gnl|CDD|36247 69 368 + 300 Gaps:33 27.82 1118 20.58 2e-07 KOG1029 KOG1029 KOG1029 Endocytic adaptor protein intersectin [Signal transduction mechanisms Intracellular trafficking secretion and vesicular transport].
rpsblast_kog gnl|CDD|35241 79 311 + 233 Gaps:24 20.77 1141 19.83 4e-07 KOG0018 KOG0018 KOG0018 Structural maintenance of chromosome protein 1 (sister chromatid cohesion complex Cohesin subunit SMC1) [Cell cycle control cell division chromosome partitioning].

7 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 570 644 75 PF08573 none DNA repair protein endonuclease SAE2/CtIP C-terminus IPR013882
Coils 342 377 36 Coil none none none
PANTHER 538 647 110 PTHR15107 none none none
Coils 163 219 57 Coil none none none
Coils 226 310 85 Coil none none none
Coils 82 110 29 Coil none none none
Coils 114 135 22 Coil none none none

0 Localization

4 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_vSeqBC_3P Qrob_Chr10 10 s_1A6CK6_610 v_7092_29 4,28 0 23,27 lod 2,8619 7
Bourran2_2015_nEpis_3P Qrob_Chr12 12 s_1AOES6_1466 s_1B0DDG_1094 28,97 28,55 30,1 lod 3.6 8.4
Bourran2_2014_nFork*_3P Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,28 7,43 41,48 lod 2,4044 5,5
Bourran1_2004_QTL4_peak_Bud_burst_3P Qrob_Chr04 4 s_1AHUWN_1101 s_1BRNG7_1618 30,55 0 47,55 lod 2,8 7,4

0 Targeting