GO Term : GO:0000077 DNA damage checkpoint GO

Namespace  biological_process Obsolete  false
description  A cell cycle checkpoint that regulates progression through the cell cycle in response to DNA damage. A DNA damage checkpoint may blocks cell cycle progression (in G1, G2 or metaphase) or slow the rate at which S phase proceeds.

0 Cross References

1 Ontology

Name
GO

14 Parents

Identifier Name Description
GO:0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0000077 DNA damage checkpoint A cell cycle checkpoint that regulates progression through the cell cycle in response to DNA damage. A DNA damage checkpoint may blocks cell cycle progression (in G1, G2 or metaphase) or slow the rate at which S phase proceeds.
GO:0007049 cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
GO:0006974 cellular response to DNA damage stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0033554 cellular response to stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0022402 cell cycle process The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.
GO:0000075 cell cycle checkpoint A cell cycle process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction.
GO:0031570 DNA integrity checkpoint A cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.

1 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0038880.2 Quercus robur 0.0 egn (M=1) KOG0018//KOG0161//KOG0933//KOG0964//KOG0965//KOG0971//KOG0996//KOG1029 - Structural maintenance of chromosome protein 1 (sister chromatid cohesion complex Cohesin subunit SMC1) [Cell cycle control cell division chromosome partitioning]. // Myosin class II heavy chain [Cytoskeleton]. // Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin subunit E) [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning]. // Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin subunit SMC3) [Cell cycle control cell division chromosome partitioning]. // Predicted RNA-binding protein contains SWAP and G-patch domains [General function prediction only]. // Microtubule-associated protein dynactin DCTN1/Glued [Cell cycle control cell division chromosome partitioning Cytoskeleton]. // Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin subunit C) [Chromatin structure and dynamics Cell cycle control cell division chromosome partitioning]. // Endocytic adaptor protein intersectin [Signal transduction mechanisms Intracellular trafficking secretion and vesicular transport].     validated

53 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0031570 GO:0000077
is_a GO:0006974 GO:0000077
part of GO:0044699 GO:0000077
part of GO:0007049 GO:0000077
part of GO:0044763 GO:0000077
is_a GO:0008150 GO:0000077
is_a GO:0033554 GO:0000077
is_a GO:0000075 GO:0000077
is_a GO:0044763 GO:0000077
part of GO:0009987 GO:0000077
is_a GO:0022402 GO:0000077
is_a GO:0044699 GO:0000077
is_a GO:0050896 GO:0000077
is_a GO:0006950 GO:0000077
is_a GO:0009987 GO:0000077
is_a GO:0051716 GO:0000077
part of GO:0008150 GO:0000077
part of GO:0000077 GO:0006977
is_a GO:0000077 GO:0007095
is_a GO:0000077 GO:0031571
is_a GO:0000077 GO:0031572
is_a GO:0000077 GO:0031573
is_a GO:0000077 GO:0044773
is_a GO:0000077 GO:0044783
part of GO:0000077 GO:0072421
part of GO:0000077 GO:0072422
part of GO:0000077 GO:0072424
part of GO:0000077 GO:0072425
part of GO:0000077 GO:0072427
part of GO:0000077 GO:0072428

1 Synonyms

Name Type
DNA damage response, signal transduction resulting in cell cycle arrest synonym