Protein : Qrob_P0139950.2 Q. robur
Protein Identifier  ? Qrob_P0139950.2 Organism . Name  Quercus robur
Score  92.0 Score Type  egn
Protein Description  (M=2) 3.1.16.1 - Spleen exonuclease. Code Enzyme  EC:3.1.16.1
Gene Prediction Quality  validated Protein length 

Sequence

Length: 535  
Kegg Orthology  K15338
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0006281 DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
GO:0004518 nuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids.

43 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pper:PRUPE_ppa015861mg 1 528 + 528 Gaps:2 86.74 611 76.42 0.0 hypothetical protein
blastp_kegg lcl|pmum:103331966 1 529 + 529 Gaps:2 83.23 638 75.89 0.0 flap endonuclease GEN-like 1
blastp_kegg lcl|fve:101297580 2 528 + 527 Gaps:1 84.35 626 73.67 0.0 flap endonuclease GEN-like 1-like
blastp_kegg lcl|pxb:103938463 1 528 + 528 Gaps:2 87.17 608 75.09 0.0 flap endonuclease GEN-like 1
blastp_kegg lcl|pxb:103932701 1 528 + 528 Gaps:2 87.17 608 74.53 0.0 flap endonuclease GEN-like 1
blastp_kegg lcl|pop:POPTR_0014s07330g 1 530 + 530 Gaps:4 86.50 615 71.43 0.0 POPTRDRAFT_663900 hypothetical protein
blastp_kegg lcl|rcu:RCOM_1613690 1 527 + 527 Gaps:2 86.86 609 69.75 0.0 DNA binding protein putative
blastp_kegg lcl|vvi:100259113 1 528 + 528 Gaps:57 87.41 667 66.55 0.0 flap endonuclease GEN-like 1
blastp_kegg lcl|cic:CICLE_v10019320mg 1 527 + 527 Gaps:10 86.15 621 70.09 0.0 hypothetical protein
blastp_kegg lcl|cit:102621447 1 527 + 527 Gaps:10 86.15 621 70.09 0.0 flap endonuclease GEN-like 1-like
blastp_pdb 2izo_A 8 249 + 242 Gaps:31 77.75 346 29.37 4e-21 mol:protein length:346 FLAP STRUCTURE-SPECIFIC ENDONUCLEASE
blastp_pdb 1b43_B 22 231 + 210 Gaps:31 69.71 340 29.11 5e-20 mol:protein length:340 PROTEIN (FEN-1)
blastp_pdb 1b43_A 22 231 + 210 Gaps:31 69.71 340 29.11 5e-20 mol:protein length:340 PROTEIN (FEN-1)
blastp_pdb 1a77_A 22 241 + 220 Gaps:25 72.09 326 29.36 2e-18 mol:protein length:326 FLAP ENDONUCLEASE-1 PROTEIN
blastp_pdb 1a76_A 22 241 + 220 Gaps:25 72.09 326 29.36 2e-18 mol:protein length:326 FLAP ENDONUCLEASE-1 PROTEIN
blastp_pdb 1mc8_B 22 275 + 254 Gaps:37 80.17 343 28.36 2e-18 mol:protein length:343 Flap Endonuclease-1
blastp_pdb 1mc8_A 22 275 + 254 Gaps:37 80.17 343 28.36 2e-18 mol:protein length:343 Flap Endonuclease-1
blastp_pdb 3q8l_A 25 242 + 218 Gaps:23 68.91 341 31.06 1e-17 mol:protein length:341 Flap endonuclease 1
blastp_pdb 3q8k_A 25 242 + 218 Gaps:23 68.91 341 31.06 1e-17 mol:protein length:341 Flap endonuclease 1
blastp_pdb 1ul1_Z 24 242 + 219 Gaps:23 62.27 379 30.93 2e-17 mol:protein length:379 Flap endonuclease-1
blastp_uniprot_sprot sp|Q9LPD2|GENL1_ARATH 1 528 + 528 Gaps:11 86.98 599 61.04 0.0 Flap endonuclease GEN-like 1 OS Arabidopsis thaliana GN GEN1 PE 2 SV 3
blastp_uniprot_sprot sp|Q64MA3|GENL1_ORYSJ 1 526 + 526 Gaps:29 87.92 629 53.16 0.0 Flap endonuclease GEN-like 1 OS Oryza sativa subsp. japonica GN RAD PE 2 SV 1
blastp_uniprot_sprot sp|Q8BMI4|GEN_MOUSE 1 452 + 452 Gaps:49 46.15 908 32.70 5e-53 Flap endonuclease GEN homolog 1 OS Mus musculus GN Gen1 PE 2 SV 2
blastp_uniprot_sprot sp|Q17RS7|GEN_HUMAN 1 452 + 452 Gaps:56 46.26 908 32.86 5e-51 Flap endonuclease GEN homolog 1 OS Homo sapiens GN GEN1 PE 1 SV 2
blastp_uniprot_sprot sp|Q8W5R1|GENL2_ORYSJ 1 282 + 282 Gaps:22 43.06 641 36.59 8e-35 Flap endonuclease GEN-like 2 OS Oryza sativa subsp. japonica GN SEND1 PE 2 SV 1
blastp_uniprot_sprot sp|Q29FC1|GEN_DROPS 1 527 + 527 Gaps:77 63.66 754 28.75 2e-30 Flap endonuclease GEN OS Drosophila pseudoobscura pseudoobscura GN Gen PE 3 SV 1
blastp_uniprot_sprot sp|Q9VRJ0|GEN_DROME 1 409 + 409 Gaps:48 53.03 726 29.87 2e-30 Flap endonuclease GEN OS Drosophila melanogaster GN Gen PE 1 SV 1
blastp_uniprot_sprot sp|Q9M2Z3|GENL2_ARATH 1 246 + 246 Gaps:14 41.33 600 35.89 8e-28 Flap endonuclease GEN-like 2 OS Arabidopsis thaliana GN GEN2 PE 2 SV 2
blastp_uniprot_sprot sp|Q9ATY5|UVH3_ARATH 1 418 + 418 Gaps:52 24.81 1479 36.78 3e-26 DNA repair protein UVH3 OS Arabidopsis thaliana GN UVH3 PE 2 SV 1
blastp_uniprot_sprot sp|Q980U8|FEN_SULSO 6 249 + 244 Gaps:31 77.65 349 29.52 7e-21 Flap endonuclease 1 OS Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) GN fen PE 1 SV 2

18 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 128 212 85 PF00867 none XPG I-region IPR006086
PANTHER 2 255 254 PTHR11081:SF23 none none none
PANTHER 345 453 109 PTHR11081:SF23 none none none
SMART 1 96 96 SM00485 none Xeroderma pigmentosum G N-region IPR006085
SUPERFAMILY 197 239 43 SSF47807 none none IPR020045
SUPERFAMILY 344 414 71 SSF47807 none none IPR020045
SUPERFAMILY 2 212 211 SSF88723 none none IPR029060
PANTHER 2 255 254 PTHR11081 none none IPR006084
PANTHER 345 453 109 PTHR11081 none none IPR006084
Pfam 1 84 84 PF00752 none XPG N-terminal domain IPR006085
SMART 127 197 71 SM00484 none Xeroderma pigmentosum G I-region IPR006086
PRINTS 147 167 21 PR00853 none Xeroderma pigmentosum group G/yeast RAD superfamily signature IPR006084
PRINTS 202 217 16 PR00853 none Xeroderma pigmentosum group G/yeast RAD superfamily signature IPR006084
PRINTS 24 38 15 PR00853 none Xeroderma pigmentosum group G/yeast RAD superfamily signature IPR006084
PRINTS 69 88 20 PR00853 none Xeroderma pigmentosum group G/yeast RAD superfamily signature IPR006084
PRINTS 126 143 18 PR00853 none Xeroderma pigmentosum group G/yeast RAD superfamily signature IPR006084
Gene3D 197 240 44 G3DSA:1.10.150.20 none none none
Gene3D 1 195 195 G3DSA:3.40.50.1010 none none IPR029060

0 Localization

9 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nLBD*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 34,91 16,12 53,62 lod 2,4961 5,2
Bourran2_2014_rEpiBC*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 35,77 14,11 55,31 lod 2,9413 6,2
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran2_2014_aSeqBC_A4 Qrob_Chr08 8 v_15999_278 v_AP13YL15_395 32,52 4,22 57,22 lod 2,7561 6,7
Bourran2_2014_nFork*_A4 Qrob_Chr08 8 PIE175 s_1CD7GJ_1398 31,22 5,24 57,24 lod 2,6724 6,8
Bourran2_2014_nPriLBD_A4 Qrob_Chr08 8 PIE175 v_9164_159 31,85 15,39 48,29 lod 2,8308 6,8
Bourran2_2015_rEpiBC_3P Qrob_Chr08 8 s_A9TNV_543 v_11837_70 9,93 9,83 11,15 lod 3.3 7.3
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL3_d13Cf Qrob_Chr08 8 v_5216_549 v_11625_20 37.08 12,26 54,9 lod 6.5888 0.04

0 Targeting