GO Term : GO:0006352 DNA-templated transcription, initiation GO

Namespace  biological_process Obsolete  false
description  Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.

0 Cross References

1 Ontology

Name
GO

31 Parents

Identifier Name Description
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016070 RNA metabolic process The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
GO:0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0006352 DNA-templated transcription, initiation Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.
GO:0006351 transcription, DNA-templated The cellular synthesis of RNA on a template of DNA.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0006139 nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0044249 cellular biosynthetic process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0006725 cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0090304 nucleic acid metabolic process Any cellular metabolic process involving nucleic acids.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0046483 heterocycle metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0034641 cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GO:1901360 organic cyclic compound metabolic process The chemical reactions and pathways involving organic cyclic compound.
GO:1901576 organic substance biosynthetic process The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.
GO:0034645 cellular macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.
GO:0044271 cellular nitrogen compound biosynthetic process The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds.
GO:0018130 heterocycle biosynthetic process The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0010467 gene expression The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GO:0034654 nucleobase-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0032774 RNA biosynthetic process The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication.
GO:0019438 aromatic compound biosynthetic process The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.
GO:0097659 nucleic acid-templated transcription The cellular synthesis of RNA on a template of nucleic acid (DNA or RNA).

26 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0007800.2 Quercus robur 29.0 egn (M=3) K03120 - transcription initiation factor TFIID TATA-box-binding protein     validated
Qrob_P0007830.2 Quercus robur 15.0 egn (M=1) KOG0444//KOG0472//KOG0532//KOG0617//KOG0618//KOG3302//KOG4658 - Cytoskeletal regulator Flightless-I (contains leucine-rich and gelsolin repeats) [Cytoskeleton]. // Leucine-rich repeat protein [Function unknown]. // Leucine-rich repeat (LRR) protein contains calponin homology domain [Cytoskeleton]. // Ras suppressor protein (contains leucine-rich repeats) [Signal transduction mechanisms]. // Serine/threonine phosphatase 2C containing leucine-rich repeats similar to SCN circadian oscillatory protein (SCOP) [Signal transduction mechanisms]. // TATA-box binding protein (TBP) component of TFIID and TFIIIB [Transcription]. // Apoptotic ATPase [Signal transduction mechanisms].     validated
Qrob_P0007850.2 Quercus robur 0.0 egn (M=3) K03120 - transcription initiation factor TFIID TATA-box-binding protein     validated
Qrob_P0007880.2 Quercus robur 95.0 egn (M=3) K03120 - transcription initiation factor TFIID TATA-box-binding protein     validated
Qrob_P0069000.2 Quercus robur 84.1 egn (M=3) PTHR11618:SF4 - TRANSCRIPTION FACTOR IIIB     validated
Qrob_P0069010.2 Quercus robur 61.1 egn (M=3) K15196 - transcription factor IIIB 90 kDa subunit     validated
Qrob_P0070400.2 Quercus robur 0.0 egn (M=2) K03124 - transcription initiation factor TFIIB     validated
Qrob_P0286100.2 Quercus robur 92.0 egn (M=2) PF02201//PF03126 - SWIB/MDM2 domain // Plus-3 domain     validated
Qrob_P0287430.2 Quercus robur 100.0 egn (M=2) K15178 - RNA polymerase-associated protein RTF1     validated
Qrob_P0321750.2 Quercus robur 100.0 egn (M=1) PTHR30603:SF4 - RNA POLYMERASE SIGMA FACTOR SIGE, CHLOROPLASTIC/MITOCHONDRIAL (PTHR30603:SF4)     validated
Qrob_P0328830.2 Quercus robur 100.0 egn (M=1) PTHR30603:SF9 - RNA POLYMERASE SIGMA FACTOR SIGF, CHLOROPLASTIC (PTHR30603:SF9)     validated
Qrob_P0340830.2 Quercus robur 100.0 egn (M=2) K15178 - RNA polymerase-associated protein RTF1     validated
Qrob_P0359120.2 Quercus robur 100.0 egn (M=4) KOG2402 - Paf1/RNA polymerase II complex RTF1 component (involved in regulation of TATA box-binding protein) [Transcription].     validated
Qrob_P0376200.2 Quercus robur 4.1 egn (M=1) K03129 - transcription initiation factor TFIID subunit 4     validated
Qrob_P0390650.2 Quercus robur 100.0 egn (M=2) K03124 - transcription initiation factor TFIIB     validated
Qrob_P0402850.2 Quercus robur 98.2 egn (M=3) K03131 - transcription initiation factor TFIID subunit 6     validated
Qrob_P0460260.2 Quercus robur 50.2 egn (M=2) PF02201//PF03126 - SWIB/MDM2 domain // Plus-3 domain     validated
Qrob_P0483600.2 Quercus robur 84.1 egn (M=3) PTHR11618:SF4 - TRANSCRIPTION FACTOR IIIB     validated
Qrob_P0533480.2 Quercus robur 100.0 egn (M=1) KOG1081//KOG1862//KOG1946//KOG2402 - Transcription factor NSD1 and related SET domain proteins [Transcription]. // GYF domain containing proteins [General function prediction only]. // RNA polymerase I transcription factor UAF [Transcription]. // Paf1/RNA polymerase II complex RTF1 component (involved in regulation of TATA box-binding protein) [Transcription].     validated
Qrob_P0572980.2 Quercus robur 19.3 egn (M=1) PTHR11618//PTHR11618:SF23 - TRANSCRIPTION INITIATION FACTOR IIB-RELATED // SUBFAMILY NOT NAMED (PTHR11618:SF23)     validated
Qrob_P0585170.2 Quercus robur 94.0 egn (M=3) K03131 - transcription initiation factor TFIID subunit 6     validated
Qrob_P0595300.2 Quercus robur 92.0 egn (M=1) PTHR30603:SF0 - RNA POLYMERASE SIGMA FACTOR RPO     validated
Qrob_P0622200.2 Quercus robur 100.0 egn (M=1) K03133 - transcription initiation factor TFIID subunit 9B     validated
Qrob_P0649410.2 Quercus robur 100.0 egn (M=1) K03126 - transcription initiation factor TFIID subunit 12     validated
Qrob_P0708870.2 Quercus robur 100.0 egn (M=1) K03086 - RNA polymerase primary sigma factor     validated
Qrob_P0736490.2 Quercus robur 100.0 egn (M=1) K03093 - RNA polymerase sigma factor     validated

101 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0006352 GO:0000999
part of GO:0006352 GO:0001020
part of GO:0006352 GO:0001021
is_a GO:0006352 GO:0001022
is_a GO:0006352 GO:0001023
is_a GO:0006352 GO:0001024
is_a GO:0006352 GO:0001036
part of GO:0006352 GO:0001043
part of GO:0006352 GO:0001112
part of GO:0006352 GO:0001113
is_a GO:0006352 GO:0001123
part of GO:0006352 GO:0001126
part of GO:0006352 GO:0001127
part of GO:0006352 GO:0001173
part of GO:0006352 GO:0001174
part of GO:0006352 GO:0001175
part of GO:0006352 GO:0001176
regulates GO:0006352 GO:0001177
regulates GO:0006352 GO:0001178
is_a GO:0006352 GO:0001180
part of GO:0006352 GO:0001188
part of GO:0006352 GO:0001189
part of GO:0006351 GO:0006352
is_a GO:0032774 GO:0006352
part of GO:0006725 GO:0006352
part of GO:0044237 GO:0006352
is_a GO:0016070 GO:0006352
part of GO:0044271 GO:0006352
is_a GO:1901362 GO:0006352
is_a GO:0090304 GO:0006352

6 Synonyms

Name Type
transcription initiation, DNA-dependent synonym
initiation of DNA-dependent transcription synonym
DNA-dependent transcription, initiation synonym
transcription initiation factor activity synonym
initiation of transcription, DNA-dependent synonym
DNA-dependent RNA polymerase complex assembly at promoter synonym