Protein : Qrob_P0402850.2 Q. robur
Protein Identifier  ? Qrob_P0402850.2 Organism . Name  Quercus robur
Score  98.2 Score Type  egn
Protein Description  (M=3) K03131 - transcription initiation factor TFIID subunit 6 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 295  
Kegg Orthology  K03131
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0005634 nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO:0006352 DNA-templated transcription, initiation Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.
GO:0046982 protein heterodimerization activity Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
GO:0051090 regulation of sequence-specific DNA binding transcription factor activity Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.

26 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pxb:103951428 1 294 + 294 Gaps:3 55.56 531 82.37 6e-172 transcription initiation factor TFIID subunit 6-like
blastp_kegg lcl|mdm:103418978 1 294 + 294 Gaps:3 55.56 531 82.03 2e-171 transcription initiation factor TFIID subunit 6-like
blastp_kegg lcl|mdm:103428076 1 294 + 294 Gaps:3 55.56 531 82.03 2e-171 transcription initiation factor TFIID subunit 6-like
blastp_kegg lcl|pmum:103326562 1 294 + 294 Gaps:3 54.73 539 82.03 2e-170 transcription initiation factor TFIID subunit 6-like
blastp_kegg lcl|fve:101312615 1 294 + 294 Gaps:3 54.83 538 82.37 2e-170 transcription initiation factor TFIID subunit 6-like
blastp_kegg lcl|pper:PRUPE_ppa003876mg 1 294 + 294 Gaps:2 54.51 543 79.73 9e-169 hypothetical protein
blastp_kegg lcl|pmum:103329185 1 294 + 294 Gaps:2 54.51 543 79.73 3e-168 transcription initiation factor TFIID subunit 6
blastp_kegg lcl|vvi:100265835 1 294 + 294 Gaps:2 54.51 543 79.39 2e-167 transcription initiation factor TFIID subunit 6-like
blastp_kegg lcl|atr:s00090p00135570 1 294 + 294 Gaps:2 54.01 548 78.38 1e-166 AMTR_s00090p00135570 hypothetical protein
blastp_kegg lcl|mus:103990477 1 294 + 294 Gaps:3 54.70 543 77.78 2e-165 transcription initiation factor TFIID subunit 6-like isoform X1
blastp_pdb 1taf_B 2 67 + 66 none 94.29 70 42.42 1e-10 mol:protein length:70 TFIID TBP ASSOCIATED FACTOR 62
blastp_uniprot_sprot sp|Q9MAU3|TAF6_ARATH 1 294 + 294 Gaps:1 53.73 549 71.86 7e-154 Transcription initiation factor TFIID subunit 6 OS Arabidopsis thaliana GN TAF6 PE 2 SV 1
blastp_uniprot_sprot sp|F4HVA6|TAF6B_ARATH 3 294 + 292 Gaps:33 57.87 527 59.34 8e-123 Transcription initiation factor TFIID subunit 6b OS Arabidopsis thaliana GN TAF6B PE 1 SV 1
blastp_uniprot_sprot sp|O74462|TAF6_SCHPO 7 294 + 288 Gaps:34 68.58 452 43.87 8e-82 Transcription initiation factor TFIID subunit 6 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN taf6 PE 1 SV 1
blastp_uniprot_sprot sp|Q91857|TAF6_XENLA 2 293 + 292 Gaps:48 52.75 618 41.41 2e-72 Transcription initiation factor TFIID subunit 6 OS Xenopus laevis GN taf6 PE 2 SV 3
blastp_uniprot_sprot sp|Q62311|TAF6_MOUSE 2 293 + 292 Gaps:55 48.82 678 39.58 2e-69 Transcription initiation factor TFIID subunit 6 OS Mus musculus GN Taf6 PE 2 SV 1
blastp_uniprot_sprot sp|P49848|TAF6_HUMAN 2 293 + 292 Gaps:55 48.89 677 39.58 2e-69 Transcription initiation factor TFIID subunit 6 OS Homo sapiens GN TAF6 PE 1 SV 1
blastp_uniprot_sprot sp|Q63801|TAF6_RAT 2 293 + 292 Gaps:55 48.82 678 39.58 2e-69 Transcription initiation factor TFIID subunit 6 OS Rattus norvegicus GN Taf6 PE 1 SV 1
blastp_uniprot_sprot sp|P49847|TAF6_DROME 2 293 + 292 Gaps:31 52.64 606 40.13 5e-68 Transcription initiation factor TFIID subunit 6 OS Drosophila melanogaster GN Taf6 PE 1 SV 2
blastp_uniprot_sprot sp|P53040|TAF6_YEAST 5 294 + 290 Gaps:58 67.44 516 37.07 3e-66 Transcription initiation factor TFIID subunit 6 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN TAF6 PE 1 SV 1
blastp_uniprot_sprot sp|Q8R2K4|TAF6L_MOUSE 4 291 + 288 Gaps:29 42.69 616 31.94 9e-30 TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L OS Mus musculus GN Taf6l PE 2 SV 1
rpsblast_cdd gnl|CDD|173968 5 294 + 290 Gaps:10 86.88 343 53.02 1e-103 cd08050 TAF6 TATA Binding Protein (TBP) Associated Factor 6 (TAF6) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex. The TATA Binding Protein (TBP) Associated Factor 6 (TAF6) is one of several TAFs that bind TBP and are involved in forming Transcription Factor IID (TFIID) complex. TFIID is one of seven General Transcription Factors (GTFs) (TFIIA TFIIB TFIID TFIIE TFIIF and TFIID) that are involved in accurate initiation of transcription by RNA polymerase II in eukaryotes. TFIID plays an important role in the recognition of promoter DNA and assembly of the pre-initiation complex. TFIID complex is composed of the TBP and at least 13 TAFs. TAFs are named after their electrophoretic mobility in polyacrylamide gels in different species. A new unified nomenclature has been suggested for the pol II TAFs to show the relationship between TAF orthologs and paralogs. Several hypotheses are proposed for TAFs functions such as serving as activator-binding sites core-promoter recognition or a role in essential catalytic activity. These TAFs with the help of specific activators are required only for expression of a subset of genes and are not universally involved for transcription as are GTFs. In yeast and human cells TAFs have been found as components of other complexes besides TFIID. Several TAFs interact via histone-fold (HFD) motifs the HFD is the interaction motif involved in heterodimerization of the core histones and their assembly into nucleosome octamers. The minimal HFD contains three alpha-helices linked by two loops and is found in core histones TAFs and many other transcription factors. TFIID has a histone octamer-like substructure. TAF6 is a shared subunit of histone acetyltransferase complex SAGA and TFIID complexes. TAF6 domain interacts with TAF9 and makes a novel histone-like heterodimer that is structurally related to histones H4 and H3. TAF6 may also interact with the downstream core promoter element (DPE).
rpsblast_cdd gnl|CDD|34698 1 294 + 294 Gaps:21 70.00 450 41.27 7e-75 COG5095 TAF6 Transcription initiation factor TFIID subunit TAF6 (also component of histone acetyltransferase SAGA) [Transcription].
rpsblast_cdd gnl|CDD|145884 1 66 + 66 none 100.00 66 57.58 2e-24 pfam02969 TAF TATA box binding protein associated factor (TAF). TAF proteins adopt a histone-like fold.
rpsblast_cdd gnl|CDD|129039 2 66 + 65 none 100.00 65 60.00 2e-22 smart00803 TAF TATA box binding protein associated factor. TAFs (TATA box binding protein associated factors) are part of the transcription initiation factor TFIID multimeric protein complex. TFIID is composed of the TATA box binding protein (TBP) and a number of TAFs. The TAFs provide binding sites for many different transcriptional activators and co-activators that modulate transcription initiation by Pol II. TAF proteins adopt a histone-like fold.
rpsblast_kog gnl|CDD|37760 1 294 + 294 Gaps:28 55.56 576 48.75 3e-91 KOG2549 KOG2549 KOG2549 Transcription initiation factor TFIID subunit TAF6 (also component of histone acetyltransferase SAGA) [Transcription].

6 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 1 66 66 G3DSA:1.10.20.10 none none IPR009072
Pfam 260 293 34 PF07571 none Protein of unknown function (DUF1546) IPR011442
SUPERFAMILY 1 66 66 SSF47113 none none IPR009072
Pfam 1 66 66 PF02969 none TATA box binding protein associated factor (TAF) IPR004823
PANTHER 1 294 294 PTHR10221 none none none
SMART 2 68 67 SM00803 none TATA box binding protein associated factor IPR004823

0 Localization

10 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran2_2014_aSeqBC_A4 Qrob_Chr08 8 v_15999_278 v_AP13YL15_395 32,52 4,22 57,22 lod 2,7561 6,7
Bourran2_2014_nFork*_A4 Qrob_Chr08 8 PIE175 s_1CD7GJ_1398 31,22 5,24 57,24 lod 2,6724 6,8
Bourran2_2014_nLBD*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,25 0 35,55 lod 2,5951 6
Bourran2_2014_nP*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,19 0 31,97 lod 2,8472 6
Bourran2_2014_nPriLBD_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,36 0 30,43 lod 2,5806 5,1
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nPriBD_3P Qrob_Chr11 11 v_11486_194 s_1AT3E_2335 5,54 0,4 20,6 lod 2,6345 5,9

0 Targeting