GO Term : GO:0004525 ribonuclease III activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.

0 Cross References

1 Ontology

Name
GO

12 Parents

Identifier Name Description
GO:0004525 ribonuclease III activity Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0004518 nuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids.
GO:0016788 hydrolase activity, acting on ester bonds Catalysis of the hydrolysis of any ester bond.
GO:0004519 endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
GO:0004521 endoribonuclease activity Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
GO:0004540 ribonuclease activity Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
GO:0032296 double-stranded RNA-specific ribonuclease activity Catalysis of the hydrolysis of phosphodiester bonds in double-stranded RNA molecules.

15 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0000690.2 Quercus robur 8.1 egn (M=1) KOG0354//KOG0701//KOG1817 - DEAD-box like helicase [General function prediction only]. // dsRNA-specific nuclease Dicer and related ribonucleases [RNA processing and modification]. // Ribonuclease [RNA processing and modification].   EC:3.1.26.3 validated
Qrob_P0288400.2 Quercus robur 100.0 egn (M=1) PF00035//PF14709 - Double-stranded RNA binding motif // double strand RNA binding domain from DEAD END PROTEIN 1     validated
Qrob_P0288410.2 Quercus robur 0.0 egn (M=1) KOG0330//KOG0331//KOG0333//KOG0338//KOG0340//KOG0343//KOG0350//KOG0354//KOG0701//KOG1817 - ATP-dependent RNA helicase [RNA processing and modification]. // ATP-dependent RNA helicase [RNA processing and modification]. // U5 snRNP-like RNA helicase subunit [RNA processing and modification]. // ATP-dependent RNA helicase [RNA processing and modification]. // ATP-dependent RNA helicase [RNA processing and modification]. // RNA Helicase [RNA processing and modification]. // DEAD-box ATP-dependent RNA helicase [RNA processing and modification]. // DEAD-box like helicase [General function prediction only]. // dsRNA-specific nuclease Dicer and related ribonucleases [RNA processing and modification]. // Ribonuclease [RNA processing and modification].   EC:3.1.26.3 validated
Qrob_P0288430.2 Quercus robur 3.1 egn (M=2) KOG0701//KOG1817 - dsRNA-specific nuclease Dicer and related ribonucleases [RNA processing and modification]. // Ribonuclease [RNA processing and modification].   EC:3.1.26.3 validated
Qrob_P0299620.2 Quercus robur 100.0 egn (M=1) KOG0328//KOG0331//KOG0335//KOG0340//KOG0344//KOG0350//KOG0354//KOG0701//KOG0952//KOG1817 - Predicted ATP-dependent RNA helicase FAL1 involved in rRNA maturation DEAD-box superfamily [Translation ribosomal structure and biogenesis]. // ATP-dependent RNA helicase [RNA processing and modification]. // ATP-dependent RNA helicase [RNA processing and modification]. // ATP-dependent RNA helicase [RNA processing and modification]. // ATP-dependent RNA helicase [RNA processing and modification]. // DEAD-box ATP-dependent RNA helicase [RNA processing and modification]. // DEAD-box like helicase [General function prediction only]. // dsRNA-specific nuclease Dicer and related ribonucleases [RNA processing and modification]. // DNA/RNA helicase MER3/SLH1 DEAD-box superfamily [RNA processing and modification]. // Ribonuclease [RNA processing and modification].   EC:3.1.26.3 validated
Qrob_P0366570.2 Quercus robur 38.1 egn (M=1) KOG0331//KOG0333//KOG0335//KOG0340//KOG0344//KOG0345//KOG0354//KOG0701//KOG1817//KOG3732 - ATP-dependent RNA helicase [RNA processing and modification]. // U5 snRNP-like RNA helicase subunit [RNA processing and modification]. // ATP-dependent RNA helicase [RNA processing and modification]. // ATP-dependent RNA helicase [RNA processing and modification]. // ATP-dependent RNA helicase [RNA processing and modification]. // ATP-dependent RNA helicase [RNA processing and modification]. // DEAD-box like helicase [General function prediction only]. // dsRNA-specific nuclease Dicer and related ribonucleases [RNA processing and modification]. // Ribonuclease [RNA processing and modification]. // Staufen and related double-stranded-RNA-binding proteins [Intracellular trafficking secretion and vesicular transport Transcription].   EC:3.1.26.3 validated
Qrob_P0366580.2 Quercus robur 70.0 egn (M=1) PF00035//PF00636//PF14709 - Double-stranded RNA binding motif // Ribonuclease III domain // double strand RNA binding domain from DEAD END PROTEIN 1   EC:3.1.26.3 validated
Qrob_P0415690.2 Quercus robur 100.0 egn (M=1) K11145 - ribonuclease III family protein     validated
Qrob_P0459960.2 Quercus robur 100.0 egn (M=1) PTHR11207//PTHR11207:SF4 - RIBONUCLEASE III // SUBFAMILY NOT NAMED (PTHR11207:SF4)   EC:3.1.26.3 validated
Qrob_P0464030.2 Quercus robur 94.0 egn (M=2) PTHR14950:SF3 - DICER-1   EC:3.1.26.3 validated
Qrob_P0534500.2 Quercus robur 100.0 egn (M=1) KOG0701//KOG1817//KOG3036//KOG3732 - dsRNA-specific nuclease Dicer and related ribonucleases [RNA processing and modification]. // Ribonuclease [RNA processing and modification]. // Protein involved in cell differentiation/sexual development [General function prediction only]. // Staufen and related double-stranded-RNA-binding proteins [Intracellular trafficking secretion and vesicular transport Transcription].   EC:3.1.26.3 validated
Qrob_P0534530.2 Quercus robur 41.5 egn (M=2) PF00035//PF00636 - Double-stranded RNA binding motif // Ribonuclease III domain   EC:3.1.26.3 validated
Qrob_P0596360.2 Quercus robur 93.1 egn (M=5) PTHR14950//PTHR14950:SF18 - HELICASE-RELATED // SUBFAMILY NOT NAMED   EC:3.1.26.3 validated
Qrob_P0619510.2 Quercus robur 0.0 egn (M=2) KOG0701//KOG1817 - dsRNA-specific nuclease Dicer and related ribonucleases [RNA processing and modification]. // Ribonuclease [RNA processing and modification].   EC:3.1.26.3 validated
Qrob_P0641840.2 Quercus robur 86.0 egn (M=3) KOG0701//KOG1817//KOG3732 - dsRNA-specific nuclease Dicer and related ribonucleases [RNA processing and modification]. // Ribonuclease [RNA processing and modification]. // Staufen and related double-stranded-RNA-binding proteins [Intracellular trafficking secretion and vesicular transport Transcription].   EC:3.1.26.3 validated

12 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016891 GO:0004525
is_a GO:0032296 GO:0004525
is_a GO:0003824 GO:0004525
is_a GO:0003674 GO:0004525
is_a GO:0004540 GO:0004525
is_a GO:0004519 GO:0004525
is_a GO:0004518 GO:0004525
is_a GO:0016893 GO:0004525
is_a GO:0016787 GO:0004525
is_a GO:0004521 GO:0004525
is_a GO:0016788 GO:0004525
is_a GO:0004525 GO:0016443

3 Synonyms

Name Type
RNase III activity synonym
pre-mRNA 3'-end processing endonuclease synonym
ribonuclease 3 activity synonym