GO Term : GO:0016443 bidentate ribonuclease III activity GO
Namespace  molecular_function Obsolete  false
description  Catalysis of the digestion of double-stranded RNAs into 20 to 30-nucleotide products. These products typically associate to the RNA-induced silencing complex and serve as guide RNAs for posttranslational RNA interference.
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0 Cross References

1 Ontology

Name
GO

13 Parents

Identifier Name Description
GO:0004525 ribonuclease III activity Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0004518 nuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids.
GO:0016788 hydrolase activity, acting on ester bonds Catalysis of the hydrolysis of any ester bond.
GO:0004519 endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
GO:0004521 endoribonuclease activity Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
GO:0004540 ribonuclease activity Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
GO:0032296 double-stranded RNA-specific ribonuclease activity Catalysis of the hydrolysis of phosphodiester bonds in double-stranded RNA molecules.
GO:0016443 bidentate ribonuclease III activity Catalysis of the digestion of double-stranded RNAs into 20 to 30-nucleotide products. These products typically associate to the RNA-induced silencing complex and serve as guide RNAs for posttranslational RNA interference.

0 Protein

12 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0004525 GO:0016443
is_a GO:0004518 GO:0016443
is_a GO:0003674 GO:0016443
is_a GO:0004519 GO:0016443
is_a GO:0016891 GO:0016443
is_a GO:0016788 GO:0016443
is_a GO:0016893 GO:0016443
is_a GO:0016787 GO:0016443
is_a GO:0032296 GO:0016443
is_a GO:0003824 GO:0016443
is_a GO:0004521 GO:0016443
is_a GO:0004540 GO:0016443

1 Synonyms

Name Type
bidentate RNase III activity synonym