GO Term : GO:0008237 metallopeptidase activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

0 Cross References

1 Ontology

Name
GO

6 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0008237 metallopeptidase activity Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
GO:0008233 peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0070011 peptidase activity, acting on L-amino acid peptides Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.

30 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0018310.2 Quercus robur 100.0 egn (M=7) 3.4.24.12 - Envelysin.   EC:3.4.24.12 validated
Qrob_P0019960.2 Quercus robur 99.0 egn (M=1) 3.4.24.16 - Neurolysin.   EC:3.4.24.16 validated
Qrob_P0057370.2 Quercus robur 100.0 egn (M=3) 3.4.24.7 - Interstitial collagenase.   EC:3.4.24.7 validated
Qrob_P0057390.2 Quercus robur 100.0 egn (M=1) 3.4.24.22 - Stromelysin 2.   EC:3.4.24.22 validated
Qrob_P0099830.2 Quercus robur 40.1 egn (M=3) 3.5.1.14 - Aminoacylase.   EC:3.5.1.14 validated
Qrob_P0099850.2 Quercus robur 100.0 egn (M=3) 3.5.1.14 - Aminoacylase.   EC:3.5.1.14 validated
Qrob_P0111110.2 Quercus robur 99.1 egn (M=7) 3.4.24.12 - Envelysin.   EC:3.4.24.12 validated
Qrob_P0131550.2 Quercus robur 96.0 egn (M=5) K08776 - puromycin-sensitive aminopeptidase [EC:3.4.11.-]   EC:3.4.11.2 validated
Qrob_P0149130.2 Quercus robur 97.0 egn (M=1) 3.4.11.14 - Cytosol alanyl aminopeptidase.   EC:3.4.11.14 validated
Qrob_P0225600.2 Quercus robur 14.1 egn (M=5) K08776 - puromycin-sensitive aminopeptidase [EC:3.4.11.-]   EC:3.4.11.2 validated
Qrob_P0225620.2 Quercus robur 0.0 egn (M=5) K08776 - puromycin-sensitive aminopeptidase [EC:3.4.11.-]   EC:3.4.11.2 validated
Qrob_P0242500.2 Quercus robur 100.0 egn (M=7) 3.4.24.12 - Envelysin.   EC:3.4.24.12 validated
Qrob_P0296720.2 Quercus robur 0.0 egn (M=2) 3.4.24.23 - Matrilysin.   EC:3.4.24.23 validated
Qrob_P0321310.2 Quercus robur 97.0 egn (M=5) K08776 - puromycin-sensitive aminopeptidase [EC:3.4.11.-]   EC:3.4.11.2 validated
Qrob_P0321360.2 Quercus robur 0.0 egn (M=8) 3.4.11.2 - Membrane alanyl aminopeptidase.   EC:3.4.11.2 validated
Qrob_P0409770.2 Quercus robur 100.0 egn (M=2) 3.4.24.34 - Neutrophil collagenase.   EC:3.4.24.34 validated
Qrob_P0409780.2 Quercus robur 90.8 egn (M=7) 3.4.24.12 - Envelysin.   EC:3.4.24.12 validated
Qrob_P0409790.2 Quercus robur 0.0 egn (M=7) 3.4.24.12 - Envelysin.   EC:3.4.24.12 validated
Qrob_P0413440.2 Quercus robur 100.0 egn (M=2) 3.3.2.6 - Leukotriene-A(4) hydrolase.   EC:3.3.2.6 validated
Qrob_P0573140.2 Quercus robur 0.0 egn (M=2) 3.4.24.34 - Neutrophil collagenase.   EC:3.4.24.34 validated
Qrob_P0578240.2 Quercus robur 0.0 egn (M=7) 3.4.24.12 - Envelysin.   EC:3.4.24.12 validated
Qrob_P0578250.2 Quercus robur 100.0 egn (M=1) 3.4.24.17 - Stromelysin 1.   EC:3.4.24.17 validated
Qrob_P0605730.2 Quercus robur 100.0 egn (M=2) 3.3.2.6 - Leukotriene-A(4) hydrolase.   EC:3.3.2.6 validated
Qrob_P0641810.2 Quercus robur 45.0 egn (M=1) KOG0264//KOG0266//KOG0272//KOG0277//KOG0302//KOG0310//KOG1046//KOG1047//KOG4328 - Nucleosome remodeling factor subunit CAF1/NURF55/MSI1 [Chromatin structure and dynamics]. // WD40 repeat-containing protein [General function prediction only]. // U4/U6 small nuclear ribonucleoprotein Prp4 (contains WD40 repeats) [RNA processing and modification]. // Peroxisomal targeting signal type 2 receptor [Intracellular trafficking secretion and vesicular transport]. // Ribosome Assembly protein [General function prediction only]. // Conserved WD40 repeat-containing protein [Function unknown]. // Puromycin-sensitive aminopeptidase and related aminopeptidases [Amino acid transport and metabolism Posttranslational modification protein turnover chaperones]. // Bifunctional leukotriene A4 hydrolase/aminopeptidase LTA4H [Lipid transport and metabolism Posttranslational modification protein turnover chaperones Defense mechanisms Amino acid transport and metabolism]. // WD40 protein [Function unknown].   EC:3.4.11.2 validated
Qrob_P0647490.2 Quercus robur 91.4 egn (M=7) 3.4.24.12 - Envelysin.   EC:3.4.24.12 validated
Qrob_P0660200.2 Quercus robur 0.0 egn (M=2) 3.4.24.70 - Oligopeptidase A.   EC:3.4.24.70 validated
Qrob_P0672460.2 Quercus robur 0.0 egn (M=2) 3.4.24.23 - Matrilysin.   EC:3.4.24.23 validated
Qrob_P0751530.2 Quercus robur 0.0 egn (M=3) 3.4.24.7 - Interstitial collagenase.   EC:3.4.24.7 validated
Qrob_P0751540.2 Quercus robur 0.0 egn (M=3) 3.4.24.7 - Interstitial collagenase.   EC:3.4.24.7 validated
Qrob_P0761160.2 Quercus robur 71.3 egn (M=1) KOG1046//KOG1932 - Puromycin-sensitive aminopeptidase and related aminopeptidases [Amino acid transport and metabolism Posttranslational modification protein turnover chaperones]. // TATA binding protein associated factor [Transcription].     validated

13 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0008237 GO:0004181
is_a GO:0008237 GO:0004222
is_a GO:0008237 GO:0008235
is_a GO:0070011 GO:0008237
is_a GO:0008233 GO:0008237
is_a GO:0003674 GO:0008237
is_a GO:0003824 GO:0008237
is_a GO:0016787 GO:0008237
is_a GO:0008237 GO:0009046
is_a GO:0008237 GO:0061473
is_a GO:0008237 GO:0070006
is_a GO:0008237 GO:0070573
is_a GO:0008237 GO:1902945

2 Synonyms

Name Type
metalloprotease activity synonym
metalloproteinase activity synonym