Protein : Qrob_P0099850.2 Q. robur
Protein Identifier  ? Qrob_P0099850.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=3) 3.5.1.14 - Aminoacylase. Code Enzyme  EC:3.5.1.14
Gene Prediction Quality  validated Protein length 

Sequence

Length: 448  
Kegg Orthology  K14677
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0 Synonyms

7 GO Terms

Identifier Name Description
GO:0005737 cytoplasm All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0006508 proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
GO:0008237 metallopeptidase activity Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
GO:0006520 cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
GO:0004046 aminoacylase activity Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid.

41 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|vvi:100260562 13 447 + 435 Gaps:13 93.56 466 76.83 0.0 aminoacylase-1-like
blastp_kegg lcl|cit:102611318 33 447 + 415 Gaps:7 94.41 447 79.15 0.0 aminoacylase-1-like
blastp_kegg lcl|pop:POPTR_0009s17030g 29 447 + 419 Gaps:10 94.42 448 78.72 0.0 POPTRDRAFT_721246 aminoacylase family protein
blastp_kegg lcl|pop:POPTR_0004s21790g 28 447 + 420 Gaps:7 93.64 456 77.52 0.0 aminoacylase family protein
blastp_kegg lcl|pmum:103334632 35 447 + 413 Gaps:7 94.81 443 79.52 0.0 aminoacylase-1
blastp_kegg lcl|cic:CICLE_v10028440mg 33 447 + 415 Gaps:10 94.37 444 79.24 0.0 hypothetical protein
blastp_kegg lcl|pper:PRUPE_ppa005858mg 35 447 + 413 Gaps:10 94.77 440 79.14 0.0 hypothetical protein
blastp_kegg lcl|pxb:103932870 33 447 + 415 Gaps:7 94.83 445 77.73 0.0 aminoacylase-1-like
blastp_kegg lcl|pxb:103949509 32 447 + 416 Gaps:7 94.84 446 76.60 0.0 aminoacylase-1-like
blastp_kegg lcl|rcu:RCOM_1565970 12 447 + 436 Gaps:12 96.30 459 76.02 0.0 Aminoacylase-1 putative (EC:3.5.1.14)
blastp_pdb 1q7l_C 31 223 + 193 none 97.47 198 49.74 1e-62 mol:protein length:198 Aminoacylase-1
blastp_pdb 1q7l_A 31 223 + 193 none 97.47 198 49.74 1e-62 mol:protein length:198 Aminoacylase-1
blastp_pdb 1q7l_D 353 433 + 81 Gaps:1 90.91 88 50.00 4e-21 mol:protein length:88 Aminoacylase-1
blastp_pdb 1q7l_B 353 433 + 81 Gaps:1 90.91 88 50.00 4e-21 mol:protein length:88 Aminoacylase-1
blastp_pdb 3isz_B 53 424 + 372 Gaps:39 92.57 377 25.50 9e-10 mol:protein length:377 Succinyl-diaminopimelate desuccinylase
blastp_pdb 3isz_A 53 424 + 372 Gaps:39 92.57 377 25.50 9e-10 mol:protein length:377 Succinyl-diaminopimelate desuccinylase
blastp_pdb 3ic1_B 53 424 + 372 Gaps:39 92.57 377 25.50 9e-10 mol:protein length:377 Succinyl-diaminopimelate desuccinylase
blastp_pdb 3ic1_A 53 424 + 372 Gaps:39 92.57 377 25.50 9e-10 mol:protein length:377 Succinyl-diaminopimelate desuccinylase
blastp_pdb 1vgy_B 53 185 + 133 Gaps:8 32.82 393 31.01 1e-07 mol:protein length:393 succinyl-diaminopimelate desuccinylase
blastp_pdb 1vgy_A 53 185 + 133 Gaps:8 32.82 393 31.01 1e-07 mol:protein length:393 succinyl-diaminopimelate desuccinylase
blastp_uniprot_sprot sp|Q99JW2|ACY1_MOUSE 29 433 + 405 Gaps:14 97.30 408 47.36 1e-124 Aminoacylase-1 OS Mus musculus GN Acy1 PE 1 SV 1
blastp_uniprot_sprot sp|Q6AYS7|ACY1A_RAT 31 433 + 403 Gaps:14 96.81 408 45.82 8e-120 Aminoacylase-1A OS Rattus norvegicus GN Acy1a PE 1 SV 1
blastp_uniprot_sprot sp|Q6PTT0|ACY1B_RAT 31 433 + 403 Gaps:14 96.81 408 45.06 6e-119 Aminoacylase-1B OS Rattus norvegicus GN Acy1b PE 1 SV 1
blastp_uniprot_sprot sp|Q03154|ACY1_HUMAN 31 433 + 403 Gaps:14 96.81 408 44.56 5e-116 Aminoacylase-1 OS Homo sapiens GN ACY1 PE 1 SV 1
blastp_uniprot_sprot sp|Q55DP8|ACY1_DICDI 38 428 + 391 Gaps:27 96.08 408 45.41 7e-116 Aminoacylase-1 OS Dictyostelium discoideum GN acy1 PE 2 SV 1
blastp_uniprot_sprot sp|P37111|ACY1_PIG 38 433 + 396 Gaps:11 95.09 407 44.44 1e-115 Aminoacylase-1 OS Sus scrofa GN ACY1 PE 1 SV 2
blastp_uniprot_sprot sp|Q5RFB0|ACY1_PONAB 31 433 + 403 Gaps:14 96.81 408 44.05 2e-115 Aminoacylase-1 OS Pongo abelii GN ACY1 PE 2 SV 2
blastp_uniprot_sprot sp|Q55FR8|CBPS2_DICDI 86 435 + 350 Gaps:72 74.76 519 25.77 2e-18 Probable carboxypeptidase S-like 2 OS Dictyostelium discoideum GN DDB_G0267984 PE 3 SV 1
blastp_uniprot_sprot sp|Q55DL1|CBPS1_DICDI 80 428 + 349 Gaps:65 75.88 485 25.82 2e-16 Probable carboxypeptidase S-like 1 OS Dictyostelium discoideum GN DDB_G0270582 PE 3 SV 1
blastp_uniprot_sprot sp|Q08BT9|P20D1_XENTR 87 203 + 117 Gaps:1 22.66 512 41.38 3e-15 Probable carboxypeptidase PM20D1 OS Xenopus tropicalis GN pm20d1 PE 2 SV 1

18 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 217 323 107 G3DSA:3.30.70.360 none none IPR011650
Gene3D 35 209 175 G3DSA:3.40.630.10 none none none
Gene3D 346 432 87 G3DSA:3.40.630.10 none none none
PANTHER 1 438 438 PTHR11014:SF56 none none none
Phobius 7 17 11 SIGNAL_PEPTIDE_H_REGION none Hydrophobic region of a signal peptide. none
ProSitePatterns 100 109 10 PS00758 none ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. IPR001261
SUPERFAMILY 35 224 190 SSF53187 none none none
SUPERFAMILY 353 433 81 SSF53187 none none none
SUPERFAMILY 219 320 102 SSF55031 none none IPR011650
Phobius 1 25 25 SIGNAL_PEPTIDE none Signal peptide region none
Pfam 101 429 329 PF01546 none Peptidase family M20/M25/M40 IPR002933
PIRSF 28 436 409 PIRSF036696 "KEGG:00330+3.5.1.14" none IPR010159
Phobius 26 447 422 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 1 6 6 SIGNAL_PEPTIDE_N_REGION none N-terminal region of a signal peptide. none
Phobius 18 25 8 SIGNAL_PEPTIDE_C_REGION none C-terminal region of a signal peptide. none
PANTHER 1 438 438 PTHR11014 none none none
TIGRFAM 33 433 401 TIGR01880 "KEGG:00330+3.5.1.14" Ac-peptdase-euk: N-acyl-L-amino-acid amidohydrolase IPR010159
ProSitePatterns 136 175 40 PS00759 none ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. IPR001261

3 Localization

Analysis Start End Length
SignalP_GRAM_NEGATIVE 1 25 24
SignalP_GRAM_POSITIVE 1 25 24
SignalP_EUK 1 25 24

0 Qtllist

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 25   Secretory pathway 1 0.954 0.025 NON-PLANT 25