Protein : Qrob_P0413440.2 Q. robur
Protein Identifier  ? Qrob_P0413440.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=2) 3.3.2.6 - Leukotriene-A(4) hydrolase. Code Enzyme  EC:3.3.2.6
Gene Prediction Quality  validated Protein length 

Sequence

Length: 616  
Kegg Orthology  K01254
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0 Synonyms

5 GO Terms

Identifier Name Description
GO:0008270 zinc ion binding Interacting selectively and non-covalently with zinc (Zn) ions.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0006508 proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
GO:0008237 metallopeptidase activity Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
GO:0019370 leukotriene biosynthetic process The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.

42 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pop:POPTR_0008s04570g 1 615 + 615 Gaps:7 100.00 622 82.64 0.0 POPTRDRAFT_832515 peptidase M1 family protein
blastp_kegg lcl|cic:CICLE_v10030974mg 1 614 + 614 Gaps:4 99.68 620 82.52 0.0 hypothetical protein
blastp_kegg lcl|rcu:RCOM_1071200 1 615 + 615 Gaps:4 100.00 619 81.42 0.0 leukotriene A-4 hydrolase putative (EC:3.3.2.6)
blastp_kegg lcl|vvi:100243305 1 615 + 615 Gaps:4 100.00 611 83.31 0.0 leukotriene A-4 hydrolase homolog
blastp_kegg lcl|tcc:TCM_043042 1 615 + 615 Gaps:4 100.00 619 82.39 0.0 Peptidase M1 family protein isoform 1
blastp_kegg lcl|cit:102629492 1 614 + 614 Gaps:4 99.68 620 82.36 0.0 leukotriene A-4 hydrolase homolog
blastp_kegg lcl|pop:POPTR_0010s22280g 4 615 + 612 Gaps:13 99.84 620 80.78 0.0 POPTRDRAFT_567536 peptidase M1 family protein
blastp_kegg lcl|pmum:103332425 1 615 + 615 Gaps:28 100.00 589 84.04 0.0 leukotriene A-4 hydrolase homolog
blastp_kegg lcl|fve:101311514 1 615 + 615 Gaps:3 100.00 612 81.05 0.0 leukotriene A-4 hydrolase homolog
blastp_kegg lcl|mdm:103446928 1 614 + 614 Gaps:4 99.84 613 78.59 0.0 leukotriene A-4 hydrolase homolog
blastp_pdb 3cia_D 5 611 + 607 Gaps:40 97.36 605 40.24 1e-135 mol:protein length:605 cold-active aminopeptidase
blastp_pdb 3cia_C 5 611 + 607 Gaps:40 97.36 605 40.24 1e-135 mol:protein length:605 cold-active aminopeptidase
blastp_pdb 3cia_B 5 611 + 607 Gaps:40 97.36 605 40.24 1e-135 mol:protein length:605 cold-active aminopeptidase
blastp_pdb 3cia_A 5 611 + 607 Gaps:40 97.36 605 40.24 1e-135 mol:protein length:605 cold-active aminopeptidase
blastp_pdb 3fun_A 17 607 + 591 Gaps:49 95.91 611 37.20 8e-116 mol:protein length:611 Leukotriene A-4 hydrolase
blastp_pdb 3fum_A 17 607 + 591 Gaps:49 95.91 611 37.20 8e-116 mol:protein length:611 Leukotriene A-4 hydrolase
blastp_pdb 3ful_A 17 607 + 591 Gaps:49 95.91 611 37.20 8e-116 mol:protein length:611 Leukotriene A-4 hydrolase
blastp_pdb 3fuk_A 17 607 + 591 Gaps:49 95.91 611 37.20 8e-116 mol:protein length:611 Leukotriene A-4 hydrolase
blastp_pdb 3fuj_A 17 607 + 591 Gaps:49 95.91 611 37.20 8e-116 mol:protein length:611 Leukotriene A-4 hydrolase
blastp_pdb 3fui_A 17 607 + 591 Gaps:49 95.91 611 37.20 8e-116 mol:protein length:611 Leukotriene A-4 hydrolase
blastp_uniprot_sprot sp|Q9FY49|LKHA4_ARATH 1 615 + 615 Gaps:3 100.00 616 74.03 0.0 Leukotriene A-4 hydrolase homolog OS Arabidopsis thaliana GN LKHA4 PE 2 SV 1
blastp_uniprot_sprot sp|Q84TA3|LKHA4_ORYSJ 1 614 + 614 Gaps:8 99.84 611 73.11 0.0 Leukotriene A-4 hydrolase homolog OS Oryza sativa subsp. japonica GN LKHA4 PE 2 SV 1
blastp_uniprot_sprot sp|Q7S785|LKHA4_NEUCR 1 608 + 608 Gaps:60 98.05 614 38.37 4e-116 Leukotriene A-4 hydrolase homolog OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) GN NCU06732 PE 3 SV 1
blastp_uniprot_sprot sp|P09960|LKHA4_HUMAN 17 607 + 591 Gaps:49 95.91 611 37.20 3e-115 Leukotriene A-4 hydrolase OS Homo sapiens GN LTA4H PE 1 SV 2
blastp_uniprot_sprot sp|Q2GY21|LKHA4_CHAGB 1 608 + 608 Gaps:56 98.53 611 36.54 5e-114 Leukotriene A-4 hydrolase homolog OS Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) GN CHGG_07133 PE 3 SV 1
blastp_uniprot_sprot sp|Q5B0W8|LKHA4_EMENI 1 613 + 613 Gaps:62 98.87 618 36.66 2e-113 Leukotriene A-4 hydrolase homolog OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN AN5812 PE 3 SV 2
blastp_uniprot_sprot sp|A6RCT2|LKHA4_AJECN 3 608 + 606 Gaps:53 96.47 623 36.94 8e-113 Leukotriene A-4 hydrolase homolog OS Ajellomyces capsulatus (strain NAm1 / WU24) GN HCAG_07440 PE 3 SV 2
blastp_uniprot_sprot sp|Q3SZH7|LKHA4_BOVIN 17 607 + 591 Gaps:63 95.91 611 36.69 2e-112 Leukotriene A-4 hydrolase OS Bos taurus GN LTA4H PE 2 SV 3
blastp_uniprot_sprot sp|A4QUC1|LKHA4_MAGO7 1 608 + 608 Gaps:75 98.04 613 37.10 1e-111 Leukotriene A-4 hydrolase homolog OS Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) GN MGG_09481 PE 3 SV 2
blastp_uniprot_sprot sp|P24527|LKHA4_MOUSE 17 607 + 591 Gaps:47 95.91 611 36.86 1e-111 Leukotriene A-4 hydrolase OS Mus musculus GN Lta4h PE 1 SV 4

14 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
SUPERFAMILY 487 611 125 SSF48371 none none IPR016024
PANTHER 1 168 168 PTHR11533 none none IPR001930
PANTHER 187 577 391 PTHR11533:SF4 none none none
SUPERFAMILY 225 462 238 SSF55486 none none none
Gene3D 317 463 147 G3DSA:1.10.390.10 none none none
SUPERFAMILY 4 218 215 SSF63737 none none none
Pfam 17 398 382 PF01433 none Peptidase family M1 IPR014782
PRINTS 304 319 16 PR00756 none Membrane alanyl dipeptidase (M1) family signature IPR014782
PRINTS 277 287 11 PR00756 none Membrane alanyl dipeptidase (M1) family signature IPR014782
PRINTS 323 335 13 PR00756 none Membrane alanyl dipeptidase (M1) family signature IPR014782
PRINTS 135 150 16 PR00756 none Membrane alanyl dipeptidase (M1) family signature IPR014782
PANTHER 187 577 391 PTHR11533 none none IPR001930
PANTHER 1 168 168 PTHR11533:SF4 none none none
Pfam 474 610 137 PF09127 "KEGG:00590+3.3.2.6","UniPathway:UPA00878" Leukotriene A4 hydrolase, C-terminal IPR015211

0 Localization

6 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nEpis*_A4 Qrob_Chr07 7 v_12400_446 s_1BPEBU_1211 6,93 0 15,13 lod 4,7411 11
Bourran2_2014_nLBD_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 37,41 9,8 50,1 lod 1,9524 4,1
Bourran2_2014_nPriBD_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,51 3,36 51,86 lod 1,6747 3,9
Bourran2_2014_nSecLBD_A4 Qrob_Chr07 7 v_8327_222 s_1A4WGY_363 16,04 0 44,69 lod 2,6373 6,5
Bourran2_2014_vEpiBC_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 37,55 14,41 50,01 lod 1,7882 4,8
Champenoux_2015_nEpis_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,53 25,47 27,72 lod 4.4 8.9

0 Targeting