GO Term : GO:0003917 DNA topoisomerase type I activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.

0 Cross References

1 Ontology

Name
GO

5 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016853 isomerase activity Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
GO:0003917 DNA topoisomerase type I activity Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.
GO:0003916 DNA topoisomerase activity Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

10 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0132020.2 Quercus robur 87.1 egn (M=2) PTHR10290 - DNA TOPOISOMERASE I   EC:5.99.1.2 validated
Qrob_P0132040.2 Quercus robur 93.1 egn (M=1) K03163 - DNA topoisomerase I [EC:5.99.1.2]   EC:5.99.1.2 validated
Qrob_P0189200.2 Quercus robur 39.0 egn (M=1) PF01131//PF01751 - DNA topoisomerase // Toprim domain   EC:5.99.1.2 validated
Qrob_P0189210.2 Quercus robur 67.3 egn (M=4) PTHR11390:SF23 - DNA TOPOISOMERASE I-RELATED   EC:5.99.1.2 validated
Qrob_P0189220.2 Quercus robur 54.0 egn (M=4) PTHR11390:SF23 - DNA TOPOISOMERASE I-RELATED   EC:5.99.1.2 validated
Qrob_P0367640.2 Quercus robur 99.0 egn (M=1) PTHR11390:SF22 - DNA TOPOISOMERASE I   EC:5.99.1.2 validated
Qrob_P0430900.2 Quercus robur 17.0 egn (M=4) PTHR11390:SF23 - DNA TOPOISOMERASE I-RELATED   EC:5.99.1.2 validated
Qrob_P0519870.2 Quercus robur 85.0 egn (M=1) 2.7.7.23 - UDP-N-acetylglucosamine diphosphorylase.   EC:2.7.7.23 validated
Qrob_P0613800.2 Quercus robur 99.0 egn (M=2) PTHR11390:SF20 - DNA TOPOISOMERASE I,III   EC:5.99.1.2 validated
Qrob_P0613810.2 Quercus robur 59.0 egn (M=1) KOG1525//KOG1957 - Sister chromatid cohesion complex Cohesin subunit PDS5 [Cell cycle control cell division chromosome partitioning]. // DNA topoisomerase III beta [Replication recombination and repair].   EC:5.99.1.2 validated

4 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0003916 GO:0003917
is_a GO:0003824 GO:0003917
is_a GO:0003674 GO:0003917
is_a GO:0016853 GO:0003917

10 Synonyms

Name Type
nicking-closing enzyme activity synonym
omega-protein activity synonym
relaxing enzyme activity synonym
swivelase activity synonym
topoisomerase synonym
DNA topoisomerase I activity synonym
deoxyribonucleate topoisomerase synonym
untwisting enzyme activity synonym
type I topoisomerase activity synonym
type I DNA topoisomerase activity synonym