Protein : Qrob_P0132040.2 Q. robur
Protein Identifier  ? Qrob_P0132040.2 Organism . Name  Quercus robur
Score  93.1 Score Type  egn
Protein Description  (M=1) K03163 - DNA topoisomerase I [EC:5.99.1.2] Code Enzyme  EC:5.99.1.2
Gene Prediction Quality  validated Protein length 

Sequence

Length: 931  
Kegg Orthology  K03163
Paste the following link
Lists
This Protein isn't in any lists. Upload a list.

Sequence Feature Displayer

Protein Sequence Displayer

J Browse Displayer

0 Synonyms

5 GO Terms

Identifier Name Description
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
GO:0006265 DNA topological change The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
GO:0005694 chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
GO:0003917 DNA topoisomerase type I activity Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.

40 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|tcc:TCM_030764 1 904 + 904 Gaps:119 87.50 904 72.44 0.0 DNA topoisomerase I alpha isoform 1
blastp_kegg lcl|csv:101223562 1 904 + 904 Gaps:138 87.29 889 72.16 0.0 DNA topoisomerase 1-like
blastp_kegg lcl|csv:101222429 1 904 + 904 Gaps:138 87.29 889 72.16 0.0 DNA topoisomerase 1-like
blastp_kegg lcl|cit:102630648 1 904 + 904 Gaps:166 87.36 902 70.43 0.0 DNA topoisomerase 1-like
blastp_kegg lcl|pper:PRUPE_ppa001622mg 196 904 + 709 Gaps:67 81.52 790 74.84 0.0 hypothetical protein
blastp_kegg lcl|cmo:103491068 1 904 + 904 Gaps:138 87.29 889 72.04 0.0 DNA topoisomerase 1-like
blastp_kegg lcl|rcu:RCOM_0045870 19 905 + 887 Gaps:138 84.85 891 71.83 0.0 DNA topoisomerase type I putative (EC:1.3.1.74)
blastp_kegg lcl|pxb:103932126 1 904 + 904 Gaps:117 87.22 884 74.84 0.0 DNA topoisomerase 1-like
blastp_kegg lcl|pxb:103958524 1 904 + 904 Gaps:117 87.22 884 74.84 0.0 DNA topoisomerase 1-like
blastp_kegg lcl|pxb:103943584 1 904 + 904 Gaps:112 87.20 883 75.06 0.0 DNA topoisomerase 1-like
blastp_pdb 2b9s_A 435 884 + 450 Gaps:41 96.06 432 53.49 4e-141 mol:protein length:432 topoisomerase I-like protein
blastp_pdb 1rrj_A 438 900 + 463 Gaps:51 77.17 565 50.92 2e-125 mol:protein length:565 DNA topoisomerase I
blastp_pdb 1seu_A 438 900 + 463 Gaps:51 73.65 592 50.92 2e-125 mol:protein length:592 DNA topoisomerase I
blastp_pdb 1a31_A 438 900 + 463 Gaps:51 73.77 591 50.92 2e-125 mol:protein length:591 PROTEIN (TOPOISOMERASE I)
blastp_pdb 1tl8_A 438 900 + 463 Gaps:51 73.65 592 50.92 2e-125 mol:protein length:592 DNA topoisomerase I
blastp_pdb 1t8i_A 438 900 + 463 Gaps:51 73.65 592 50.92 2e-125 mol:protein length:592 DNA topoisomerase I
blastp_pdb 1sc7_A 438 900 + 463 Gaps:51 73.65 592 50.92 2e-125 mol:protein length:592 DNA topoisomerase I
blastp_pdb 1k4t_A 438 900 + 463 Gaps:51 73.65 592 50.92 2e-125 mol:protein length:592 DNA topoisomerase I
blastp_pdb 1k4s_A 438 900 + 463 Gaps:51 73.65 592 50.92 2e-125 mol:protein length:592 DNA topoisomerase I
blastp_pdb 1lpq_A 438 900 + 463 Gaps:51 77.30 564 50.92 2e-125 mol:protein length:564 DNA topoisomerase I
blastp_uniprot_sprot sp|P30181|TOP1_ARATH 205 904 + 700 Gaps:92 77.07 916 62.04 0.0 DNA topoisomerase 1 OS Arabidopsis thaliana GN TOP1 PE 1 SV 1
blastp_uniprot_sprot sp|P93119|TOP1_DAUCA 201 923 + 723 Gaps:121 83.54 790 60.61 0.0 DNA topoisomerase 1 OS Daucus carota GN TOP1 PE 2 SV 1
blastp_uniprot_sprot sp|P07799|TOP1_SCHPO 434 917 + 484 Gaps:44 55.53 814 53.76 6e-147 DNA topoisomerase 1 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN top1 PE 1 SV 2
blastp_uniprot_sprot sp|Q54RC3|TOP1_DICDI 438 912 + 475 Gaps:42 49.61 893 52.14 4e-146 DNA topoisomerase 1 OS Dictyostelium discoideum GN top1 PE 3 SV 1
blastp_uniprot_sprot sp|P04786|TOP1_YEAST 434 917 + 484 Gaps:49 59.17 769 52.31 3e-144 DNA topoisomerase 1 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN TOP1 PE 1 SV 2
blastp_uniprot_sprot sp|Q969P6|TOP1M_HUMAN 438 900 + 463 Gaps:51 72.55 601 50.23 5e-134 DNA topoisomerase I mitochondrial OS Homo sapiens GN TOP1MT PE 2 SV 1
blastp_uniprot_sprot sp|A9Q1D5|TOP1M_PANTR 438 900 + 463 Gaps:51 72.55 601 50.00 2e-132 DNA topoisomerase I mitochondrial OS Pan troglodytes GN TOP1MT PE 2 SV 1
blastp_uniprot_sprot sp|P30189|TOP1_DROME 438 900 + 463 Gaps:48 44.75 972 51.49 8e-131 DNA topoisomerase 1 OS Drosophila melanogaster GN Top1 PE 1 SV 1
blastp_uniprot_sprot sp|Q00313|TOP1_CANAX 433 917 + 485 Gaps:47 58.35 778 50.22 5e-127 DNA topoisomerase 1 OS Candida albicans GN TOP1 PE 3 SV 1
blastp_uniprot_sprot sp|O17966|TOP1_CAEEL 438 898 + 461 Gaps:62 54.71 806 54.42 6e-126 DNA topoisomerase 1 OS Caenorhabditis elegans GN top-1 PE 2 SV 1

25 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 454 476 23 G3DSA:1.10.10.41 none none IPR013034
Gene3D 512 573 62 G3DSA:1.10.10.41 none none IPR013034
SUPERFAMILY 432 477 46 SSF56741 none none IPR008336
SUPERFAMILY 688 893 206 SSF56349 none none IPR011010
Gene3D 688 830 143 G3DSA:3.90.15.10 none none IPR014711
Pfam 437 476 40 PF02919 none Eukaryotic DNA topoisomerase I, DNA binding fragment IPR008336
Pfam 511 685 175 PF02919 none Eukaryotic DNA topoisomerase I, DNA binding fragment IPR008336
Gene3D 837 904 68 G3DSA:1.10.132.10 none none IPR014727
PANTHER 512 904 393 PTHR10290 none none none
PANTHER 298 475 178 PTHR10290 none none none
PANTHER 65 266 202 PTHR10290 none none none
SUPERFAMILY 511 687 177 SSF56741 none none IPR008336
PRINTS 614 623 10 PR00416 none Eukaryotic DNA topoisomerase I signature IPR001631
PRINTS 775 791 17 PR00416 none Eukaryotic DNA topoisomerase I signature IPR001631
PRINTS 730 749 20 PR00416 none Eukaryotic DNA topoisomerase I signature IPR001631
PRINTS 753 767 15 PR00416 none Eukaryotic DNA topoisomerase I signature IPR001631
PRINTS 833 847 15 PR00416 none Eukaryotic DNA topoisomerase I signature IPR001631
PANTHER 512 904 393 PTHR10290:SF3 none none none
PANTHER 298 475 178 PTHR10290:SF3 none none none
PANTHER 65 266 202 PTHR10290:SF3 none none none
Gene3D 433 453 21 G3DSA:2.170.11.10 none none IPR013030
Gene3D 574 687 114 G3DSA:2.170.11.10 none none IPR013030
Pfam 687 904 218 PF01028 none Eukaryotic DNA topoisomerase I, catalytic core IPR013500
SMART 614 927 314 SM00435 none DNA Topoisomerase I (eukaryota) IPR013499
Coils 563 592 30 Coil none none none

0 Localization

10 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran2_2014_aSeqBC_A4 Qrob_Chr08 8 v_15999_278 v_AP13YL15_395 32,52 4,22 57,22 lod 2,7561 6,7
Bourran2_2014_nFork*_A4 Qrob_Chr08 8 PIE175 s_1CD7GJ_1398 31,22 5,24 57,24 lod 2,6724 6,8
Bourran2_2014_nLBD*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,25 0 35,55 lod 2,5951 6
Bourran2_2014_nP*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,19 0 31,97 lod 2,8472 6
Bourran2_2014_nPriLBD_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,36 0 30,43 lod 2,5806 5,1
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nPriBD_3P Qrob_Chr11 11 v_11486_194 s_1AT3E_2335 5,54 0,4 20,6 lod 2,6345 5,9

0 Targeting