Protein : Qrob_P0367640.2 Q. robur
Protein Identifier  ? Qrob_P0367640.2 Organism . Name  Quercus robur
Score  99.0 Score Type  egn
Protein Description  (M=1) PTHR11390:SF22 - DNA TOPOISOMERASE I Code Enzyme  EC:5.99.1.2
Gene Prediction Quality  validated Protein length 

Sequence

Length: 800  
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0 Synonyms

5 GO Terms

Identifier Name Description
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0006265 DNA topological change The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
GO:0005694 chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
GO:0003917 DNA topoisomerase type I activity Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.
GO:0003916 DNA topoisomerase activity Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.

42 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pmum:103320114 37 796 + 760 Gaps:7 64.47 1171 78.68 0.0 uncharacterized LOC103320114
blastp_kegg lcl|vvi:100247441 37 796 + 760 Gaps:1 64.05 1185 78.13 0.0 DNA topoisomerase 1-like
blastp_kegg lcl|fve:101314719 45 796 + 752 Gaps:2 64.00 1175 77.39 0.0 DNA topoisomerase 1-like
blastp_kegg lcl|pxb:103944567 36 796 + 761 Gaps:3 64.74 1177 77.95 0.0 DNA topoisomerase 3
blastp_kegg lcl|pper:PRUPE_ppa001428mg 89 796 + 708 Gaps:1 85.32 831 81.38 0.0 hypothetical protein
blastp_kegg lcl|tcc:TCM_036747 37 796 + 760 Gaps:5 74.88 1011 77.81 0.0 DNA topoisomerase isoform 1
blastp_kegg lcl|pop:POPTR_0006s29400g 46 796 + 751 Gaps:6 66.52 1120 76.51 0.0 hypothetical protein
blastp_kegg lcl|mdm:103456080 36 796 + 761 Gaps:5 69.45 1100 75.92 0.0 DNA topoisomerase 3-beta-1-like
blastp_kegg lcl|pxb:103957527 36 796 + 761 Gaps:4 65.05 1173 74.97 0.0 uncharacterized LOC103957527
blastp_kegg lcl|cit:102624144 35 796 + 762 Gaps:6 65.69 1160 75.72 0.0 uncharacterized LOC102624144
blastp_pdb 2gaj_B 109 700 + 592 Gaps:46 86.26 633 42.31 2e-117 mol:protein length:633 DNA topoisomerase I
blastp_pdb 2gaj_A 109 700 + 592 Gaps:46 86.26 633 42.31 2e-117 mol:protein length:633 DNA topoisomerase I
blastp_pdb 2gai_B 109 700 + 592 Gaps:46 86.26 633 42.31 2e-117 mol:protein length:633 DNA topoisomerase I
blastp_pdb 2gai_A 109 700 + 592 Gaps:46 86.26 633 42.31 2e-117 mol:protein length:633 DNA topoisomerase I
blastp_pdb 1cy8_A 108 695 + 588 Gaps:73 96.33 599 40.21 2e-114 mol:protein length:599 DNA TOPOISOMERASE I
blastp_pdb 1cy7_A 108 695 + 588 Gaps:73 96.33 599 40.21 2e-114 mol:protein length:599 DNA TOPOISOMERASE I
blastp_pdb 1cy6_A 108 695 + 588 Gaps:73 96.33 599 40.21 2e-114 mol:protein length:599 DNA TOPOISOMERASE I
blastp_pdb 1cy4_A 108 695 + 588 Gaps:73 96.33 599 40.21 2e-114 mol:protein length:599 DNA TOPOISOMERASE I
blastp_pdb 1cy2_A 108 695 + 588 Gaps:73 96.33 599 40.21 2e-114 mol:protein length:599 DNA TOPOISOMERASE I
blastp_pdb 1cy1_A 108 695 + 588 Gaps:73 96.33 599 40.21 2e-114 mol:protein length:599 DNA TOPOISOMERASE I
blastp_uniprot_sprot sp|Q1RIM1|TOP1_RICBR 111 786 + 676 Gaps:23 82.12 800 46.42 0.0 DNA topoisomerase 1 OS Rickettsia bellii (strain RML369-C) GN topA PE 3 SV 1
blastp_uniprot_sprot sp|Q4UM42|TOP1_RICFE 111 786 + 676 Gaps:33 84.66 776 46.27 0.0 DNA topoisomerase 1 OS Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) GN topA PE 3 SV 1
blastp_uniprot_sprot sp|Q92IH1|TOP1_RICCN 111 786 + 676 Gaps:23 84.66 776 45.51 0.0 DNA topoisomerase 1 OS Rickettsia conorii (strain ATCC VR-613 / Malish 7) GN topA PE 3 SV 1
blastp_uniprot_sprot sp|Q68X45|TOP1_RICTY 111 786 + 676 Gaps:23 84.34 779 45.66 0.0 DNA topoisomerase 1 OS Rickettsia typhi (strain ATCC VR-144 / Wilmington) GN topA PE 3 SV 1
blastp_uniprot_sprot sp|Q9ZDK2|TOP1_RICPR 111 786 + 676 Gaps:23 84.66 776 45.51 0.0 DNA topoisomerase 1 OS Rickettsia prowazekii (strain Madrid E) GN topA PE 3 SV 1
blastp_uniprot_sprot sp|Q9X3X7|TOP1_ZYMMO 111 791 + 681 Gaps:49 53.30 1212 46.44 2e-175 DNA topoisomerase 1 OS Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) GN topA PE 3 SV 3
blastp_uniprot_sprot sp|Q9PEV8|TOP1_XYLFA 109 693 + 585 Gaps:31 70.18 815 44.06 2e-152 DNA topoisomerase 1 OS Xylella fastidiosa (strain 9a5c) GN topA PE 3 SV 1
blastp_uniprot_sprot sp|Q87AQ6|TOP1_XYLFT 109 693 + 585 Gaps:33 70.18 815 44.76 5e-152 DNA topoisomerase 1 OS Xylella fastidiosa (strain Temecula1 / ATCC 700964) GN topA PE 3 SV 1
blastp_uniprot_sprot sp|P39814|TOP1_BACSU 111 759 + 649 Gaps:62 93.63 691 42.66 5e-146 DNA topoisomerase 1 OS Bacillus subtilis (strain 168) GN topA PE 3 SV 1
blastp_uniprot_sprot sp|Q9KA23|TOP1_BACHD 111 759 + 649 Gaps:58 93.77 690 40.19 1e-145 DNA topoisomerase 1 OS Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) GN topA PE 3 SV 1

24 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 724 760 37 PF01396 none Topoisomerase DNA binding C4 zinc finger IPR013498
SUPERFAMILY 724 732 9 SSF56712 none none IPR023405
SUPERFAMILY 109 695 587 SSF56712 none none IPR023405
Pfam 111 224 114 PF01751 none Toprim domain IPR006171
ProSitePatterns 400 423 24 PS00396 none Prokaryotic DNA topoisomerase I active site. IPR023406
Gene3D 441 590 150 G3DSA:2.70.20.10 none none IPR013825
Gene3D 295 436 142 G3DSA:2.70.20.10 none none IPR013825
PRINTS 492 508 17 PR00417 none Prokaryotic DNA topoisomerase I signature IPR000380
PRINTS 607 621 15 PR00417 none Prokaryotic DNA topoisomerase I signature IPR000380
PRINTS 183 196 14 PR00417 none Prokaryotic DNA topoisomerase I signature IPR000380
PRINTS 414 423 10 PR00417 none Prokaryotic DNA topoisomerase I signature IPR000380
PRINTS 273 291 19 PR00417 none Prokaryotic DNA topoisomerase I signature IPR000380
Pfam 238 681 444 PF01131 none DNA topoisomerase IPR013497
TIGRFAM 112 759 648 TIGR01051 none topA_bact: DNA topoisomerase I IPR005733
Gene3D 246 293 48 G3DSA:1.10.460.10 none none IPR013824
Gene3D 591 730 140 G3DSA:1.10.460.10 none none IPR013824
PANTHER 71 783 713 PTHR11390 none none IPR000380
PANTHER 71 783 713 PTHR11390:SF22 none none none
SMART 363 644 282 SM00437 none Bacterial DNA topoisomerase I DNA-binding domain IPR003602
SMART 215 303 89 SM00436 none Bacterial DNA topoisomeraes I ATP-binding domain IPR003601
ProSiteProfiles 109 225 117 PS50880 none Toprim domain profile. IPR006171
SMART 109 209 101 SM00493 none none IPR006171
Hamap 109 796 688 MF_00952 none DNA topoisomerase 1 [topA]. IPR028612
Gene3D 109 245 137 G3DSA:3.40.50.140 none none IPR006171

1 Localization

Analysis Start End Length
SignalP_GRAM_POSITIVE 1 19 18

20 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran1_2003_QTL2_peak_Bud_burst_A4 Qrob_Chr02 2 s_1B0H8U_259 s_1CB1VL_554 17 0 87 lod 3,3 8,7
Bourran2_2004_QTL9_peak_Bud_burst_3P Qrob_Chr02 2 s_1C34E9_788 v_12238_322 50 25 75 lod 4,4 10,1
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL2_d13Cf Qrob_Chr02 2 s_1AQA4Z_1644 s_1AK5QX_947 53.67 14,01 79,68 lod 5.6594 0.03
Bourran1_2004_QTL2_peak_Bud_burst_3P Qrob_Chr02 2 s_1AW12F_382 s_1A77MR_223 42 6 64 lod 3,6 9,6
Bourran2_2002_QTL7_peak_Bud_burst_3P Qrob_Chr02 2 s_1ANG6_1446 v_11270_161 40 29 52 lod 8,1 16
Bourran2_2002_QTL9_peak_Bud_burst_A4 Qrob_Chr02 2 s_1BFNDA_375 s_1A3VA1_2139 32,5 17 62 lod 3,1 4,2
Bourran2_2003_QTL8_peak_Bud_burst_3P Qrob_Chr02 2 s_1ANG6_1446 v_11270_161 40 0 72 lod 4,4 9,9
Bourran2_2014_nP_A4 Qrob_Chr11 11 s_1B58GB_1413 s_1A5BYY_1671 11,15 0 42,38 lod 1,8913 4,5
Bourran2_2015_nP_A4 Qrob_Chr02 2 s_1A0FUE_1868 s_1A1UAI_500 20,64 20,47 21,36 lod 5.8 10.9
Bourran2_2015_nPriLBD_A4 Qrob_Chr02 2 s_1CP5DI_1183 s_1A63ZX_1277 24,87 24,63 26,18 lod 3.8 7
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL6_d13Cf Qrob_Chr02 2 s_1AEP21_172 v_6048_204 46.33 22,5 65,23 lod 4.972 0.03
Bourran2_2015_nEpis_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 34,94 34,88 37,45 lod 3.1 7
Bourran2_2015_nSecLBD_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 35,81 34,88 37,45 lod 4.4 10.4
Bourran1_2003_QTL1_peak_Bud_burst_3P Qrob_Chr02 2 s_1AR8KI_1183 s_1B0QB1_473 22 6 41 lod 4,2 11,5
Bourran1_2004_QTL3_peak_Bud_burst_A4 Qrob_Chr02 2 s_1B0H8U_259 s_1CB1VL_554 17 0 46 lod 2,9 6,4
Bourran2_2015_nEpiBC_A4 Qrob_Chr07 7 s_1DP9TW_798 v_8128_173 22,61 22,14 22,73 lod 3.1 8.5
Champenoux_2015_nEpis_A4 Qrob_Chr02 2 s_1BAGIZ_823 s_1BN4CB_644 23,06 23,06 23,06 lod 4.9 11
Champenoux_2015_nP_A4 Qrob_Chr02 2 s_1BN4CB_644 v_508_128 23,76 23,06 24,51 lod 2.8 6.2
Champenoux_2015_nPriLBD_A4 Qrob_Chr02 2 s_1CP5DI_1183 s_1A63ZX_1277 25,35 24,63 26,18 lod 4.0 8.7
Champenoux_2015_nSecLBD_A4 Qrob_Chr02 2 s_1AN4ZM_1665 v_8587_238 18,52 18,89 18,27 lod 3.2 7.4

0 Targeting