Protein : Qrob_P0613800.2 Q. robur
Protein Identifier  ? Qrob_P0613800.2 Organism . Name  Quercus robur
Score  99.0 Score Type  egn
Protein Description  (M=2) PTHR11390:SF20 - DNA TOPOISOMERASE I,III Code Enzyme  EC:5.99.1.2
Gene Prediction Quality  validated Protein length 

Sequence

Length: 204  
Kegg Orthology  K03165
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0006265 DNA topological change The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
GO:0003917 DNA topoisomerase type I activity Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.
GO:0003916 DNA topoisomerase activity Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.

42 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|fve:101301962 3 182 + 180 none 20.88 862 83.33 1e-99 DNA topoisomerase 3-beta-1-like
blastp_kegg lcl|pxb:103960364 3 182 + 180 none 20.88 862 83.33 1e-99 DNA topoisomerase 3-beta
blastp_kegg lcl|mdm:103400621 3 182 + 180 none 20.88 862 83.33 6e-99 DNA topoisomerase 3-beta-1
blastp_kegg lcl|pper:PRUPE_ppa001274mg 3 182 + 180 none 20.79 866 83.33 5e-98 hypothetical protein
blastp_kegg lcl|vvi:100260076 3 182 + 180 none 20.13 894 83.89 8e-98 DNA topoisomerase 3-beta-1-like
blastp_kegg lcl|cic:CICLE_v10006835mg 5 182 + 178 none 40.00 445 79.78 1e-97 hypothetical protein
blastp_kegg lcl|pmum:103322635 3 182 + 180 none 20.79 866 82.22 4e-97 DNA topoisomerase 3-beta-1
blastp_kegg lcl|rcu:RCOM_1646110 3 182 + 180 none 20.81 865 82.78 8e-97 prokaryotic DNA topoisomerase putative (EC:5.99.1.2)
blastp_kegg lcl|cam:101498855 3 193 + 191 Gaps:4 22.70 859 74.36 6e-96 DNA topoisomerase 3-beta-1-like
blastp_kegg lcl|gmx:100791807 6 182 + 177 none 20.51 863 79.10 2e-94 DNA topoisomerase 3-beta-1-like
blastp_pdb 1mw9_X 26 176 + 151 Gaps:3 25.68 592 26.32 9e-08 mol:protein length:592 DNA Topoisomerase I
blastp_pdb 1mw8_X 26 176 + 151 Gaps:3 25.68 592 26.32 9e-08 mol:protein length:592 DNA Topoisomerase I
blastp_pdb 1ecl_A 26 176 + 151 Gaps:3 25.46 597 26.32 1e-07 mol:protein length:597 ESCHERICHIA COLI TOPOISOMERASE I
blastp_pdb 3px7_A 26 176 + 151 Gaps:3 25.55 595 26.32 1e-07 mol:protein length:595 DNA topoisomerase
blastp_pdb 1cy8_A 26 176 + 151 Gaps:3 25.38 599 26.32 1e-07 mol:protein length:599 DNA TOPOISOMERASE I
blastp_pdb 1cy7_A 26 176 + 151 Gaps:3 25.38 599 26.32 1e-07 mol:protein length:599 DNA TOPOISOMERASE I
blastp_pdb 1cy6_A 26 176 + 151 Gaps:3 25.38 599 26.32 1e-07 mol:protein length:599 DNA TOPOISOMERASE I
blastp_pdb 1cy4_A 26 176 + 151 Gaps:3 25.38 599 26.32 1e-07 mol:protein length:599 DNA TOPOISOMERASE I
blastp_pdb 1cy2_A 26 176 + 151 Gaps:3 25.38 599 26.32 1e-07 mol:protein length:599 DNA TOPOISOMERASE I
blastp_pdb 1cy1_A 26 176 + 151 Gaps:3 25.38 599 26.32 1e-07 mol:protein length:599 DNA TOPOISOMERASE I
blastp_uniprot_sprot sp|Q9Z321|TOP3B_MOUSE 5 185 + 181 Gaps:1 21.11 862 52.20 9e-58 DNA topoisomerase 3-beta-1 OS Mus musculus GN Top3b PE 2 SV 1
blastp_uniprot_sprot sp|O95985|TOP3B_HUMAN 5 185 + 181 Gaps:1 21.11 862 50.55 3e-57 DNA topoisomerase 3-beta-1 OS Homo sapiens GN TOP3B PE 2 SV 1
blastp_uniprot_sprot sp|O96651|TOP3B_DROME 5 185 + 181 Gaps:1 20.80 875 50.55 3e-56 DNA topoisomerase 3-beta OS Drosophila melanogaster GN Top3beta PE 2 SV 2
blastp_uniprot_sprot sp|O70157|TOP3A_MOUSE 5 183 + 179 none 17.85 1003 32.40 2e-28 DNA topoisomerase 3-alpha OS Mus musculus GN Top3a PE 2 SV 1
blastp_uniprot_sprot sp|Q13472|TOP3A_HUMAN 5 183 + 179 none 17.88 1001 32.40 2e-27 DNA topoisomerase 3-alpha OS Homo sapiens GN TOP3A PE 1 SV 1
blastp_uniprot_sprot sp|Q8T2T7|TOP3_DICDI 5 180 + 176 none 21.26 828 30.11 5e-27 DNA topoisomerase 3 OS Dictyostelium discoideum GN top3 PE 3 SV 1
blastp_uniprot_sprot sp|O61660|TOP3_CAEEL 5 182 + 178 none 23.45 759 33.15 6e-27 DNA topoisomerase 3 OS Caenorhabditis elegans GN top-3 PE 2 SV 1
blastp_uniprot_sprot sp|Q9NG98|TOP3A_DROME 5 186 + 182 none 14.56 1250 31.32 5e-24 DNA topoisomerase 3-alpha OS Drosophila melanogaster GN Top3alpha PE 2 SV 2
blastp_uniprot_sprot sp|P13099|TOP3_YEAST 14 166 + 153 Gaps:6 24.24 656 34.59 5e-23 DNA topoisomerase 3 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN TOP3 PE 1 SV 1
blastp_uniprot_sprot sp|O60126|TOP3_SCHPO 5 188 + 184 Gaps:8 30.87 622 29.69 5e-20 DNA topoisomerase 3 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN top3 PE 1 SV 2

7 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 5 182 178 PTHR11390 none none IPR000380
SMART 1 120 120 SM00437 none Bacterial DNA topoisomerase I DNA-binding domain IPR003602
Gene3D 5 65 61 G3DSA:2.70.20.10 none none IPR013825
SUPERFAMILY 4 172 169 SSF56712 none none IPR023405
Pfam 5 157 153 PF01131 none DNA topoisomerase IPR013497
Gene3D 66 171 106 G3DSA:1.10.460.10 none none IPR013824
PANTHER 5 182 178 PTHR11390:SF20 none none none

0 Localization

16 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Champenoux_2015_nPriLBD_3P Qrob_Chr10 10 v_15000_157 v_15000_310 15,68 15,9 15,91 lod 2.4 5.5
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2014_nLBD*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,25 0 35,55 lod 2,5951 6
Bourran2_2014_nP*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,19 0 31,97 lod 2,8472 6
Bourran2_2002_QTL11_peak_Bud_burst_A4 Qrob_Chr06 6 s_1C41PA_791 s_1AM1AV_1141 19,17 0 34,57 lod 2,3 2,9
Bourran2_2014_aSeqBC_3P Qrob_Chr06 6 v_506_189 v_686_77 30,72 13,58 43,48 lod 2,2746 6,3
Bourran2_2014_aSeqBC*_A4 Qrob_Chr06 6 s_2F5MK3_712 v_444_355 27,13 14,86 39,46 lod 3,7847 9,8
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nEpis*_A4 Qrob_Chr07 7 v_12400_446 s_1BPEBU_1211 6,93 0 15,13 lod 4,7411 11
Bourran2_2014_nFork*_3P Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,28 7,43 41,48 lod 2,4044 5,5
Bourran2_2014_nLBD_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 37,41 9,8 50,1 lod 1,9524 4,1
Bourran2_2014_nPriBD_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,51 3,36 51,86 lod 1,6747 3,9
Bourran2_2014_nSecLBD_A4 Qrob_Chr07 7 v_8327_222 s_1A4WGY_363 16,04 0 44,69 lod 2,6373 6,5
Bourran2_2014_vEpiBC_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 37,55 14,41 50,01 lod 1,7882 4,8
Champenoux_2015_nEpis_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,53 25,47 27,72 lod 4.4 8.9
Champenoux_2015_nP_3P Qrob_Chr06 6 s_1A386O_228 s_1AYZFS_603 27,03 26,47 27,34 lod 2.8 7.2

0 Targeting