Protein : Qrob_P0189200.2 Q. robur
Protein Identifier  ? Qrob_P0189200.2 Organism . Name  Quercus robur
Score  39.0 Score Type  egn
Protein Description  (M=1) PF01131//PF01751 - DNA topoisomerase // Toprim domain Code Enzyme  EC:5.99.1.2
Gene Prediction Quality  validated Protein length 

Sequence

Length: 462  
Kegg Orthology  K03165
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0006265 DNA topological change The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
GO:0003917 DNA topoisomerase type I activity Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.
GO:0003916 DNA topoisomerase activity Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.

42 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|mdm:103431441 7 438 + 432 Gaps:29 85.69 538 80.69 0.0 DNA topoisomerase 3-alpha-like
blastp_kegg lcl|pper:PRUPE_ppa020488mg 10 438 + 429 Gaps:29 84.13 542 80.70 0.0 hypothetical protein
blastp_kegg lcl|pxb:103946776 5 438 + 434 Gaps:29 47.63 972 80.35 0.0 DNA topoisomerase 3-alpha
blastp_kegg lcl|pvu:PHAVU_009G154800g 10 438 + 429 Gaps:29 65.80 693 79.17 0.0 hypothetical protein
blastp_kegg lcl|vvi:100248256 10 438 + 429 Gaps:29 49.89 914 79.82 0.0 DNA topoisomerase 3-alpha-like
blastp_kegg lcl|cam:101494498 7 438 + 432 Gaps:29 49.89 920 79.08 0.0 DNA topoisomerase 3-alpha-like
blastp_kegg lcl|fve:101293143 10 438 + 429 Gaps:29 50.22 908 80.26 0.0 DNA topoisomerase 3-alpha-like
blastp_kegg lcl|csv:101224272 1 438 + 438 Gaps:32 76.11 607 77.27 0.0 DNA topoisomerase 3-like
blastp_kegg lcl|pmum:103327049 10 438 + 429 Gaps:30 50.22 910 79.65 0.0 DNA topoisomerase 3-alpha
blastp_kegg lcl|cic:CICLE_v10003112mg 1 438 + 438 Gaps:32 58.19 794 79.00 0.0 hypothetical protein
blastp_pdb 1d6m_A 13 430 + 418 Gaps:89 66.92 653 27.69 7e-12 mol:protein length:653 DNA TOPOISOMERASE III
blastp_pdb 2o5e_B 13 430 + 418 Gaps:89 66.31 659 27.69 7e-12 mol:protein length:659 DNA topoisomerase 3
blastp_pdb 2o5e_A 13 430 + 418 Gaps:89 66.31 659 27.69 7e-12 mol:protein length:659 DNA topoisomerase 3
blastp_pdb 2o5c_B 13 430 + 418 Gaps:89 66.31 659 27.69 7e-12 mol:protein length:659 DNA topoisomerase 3
blastp_pdb 2o5c_A 13 430 + 418 Gaps:89 66.31 659 27.69 7e-12 mol:protein length:659 DNA topoisomerase 3
blastp_pdb 2o59_B 13 430 + 418 Gaps:89 66.31 659 27.69 7e-12 mol:protein length:659 DNA topoisomerase 3
blastp_pdb 2o59_A 13 430 + 418 Gaps:89 66.31 659 27.69 7e-12 mol:protein length:659 DNA topoisomerase 3
blastp_pdb 2o54_B 13 430 + 418 Gaps:89 66.31 659 27.69 7e-12 mol:protein length:659 DNA topoisomerase 3
blastp_pdb 2o54_A 13 430 + 418 Gaps:89 66.31 659 27.69 7e-12 mol:protein length:659 DNA topoisomerase 3
blastp_pdb 2o19_B 13 430 + 418 Gaps:89 66.31 659 27.69 7e-12 mol:protein length:659 DNA topoisomerase 3
blastp_uniprot_sprot sp|Q13472|TOP3A_HUMAN 8 438 + 431 Gaps:40 44.66 1001 48.99 7e-135 DNA topoisomerase 3-alpha OS Homo sapiens GN TOP3A PE 1 SV 1
blastp_uniprot_sprot sp|O70157|TOP3A_MOUSE 8 438 + 431 Gaps:40 44.57 1003 48.77 8e-134 DNA topoisomerase 3-alpha OS Mus musculus GN Top3a PE 2 SV 1
blastp_uniprot_sprot sp|Q8T2T7|TOP3_DICDI 11 439 + 429 Gaps:65 57.49 828 44.33 2e-124 DNA topoisomerase 3 OS Dictyostelium discoideum GN top3 PE 3 SV 1
blastp_uniprot_sprot sp|Q9NG98|TOP3A_DROME 7 455 + 449 Gaps:53 36.48 1250 46.05 7e-118 DNA topoisomerase 3-alpha OS Drosophila melanogaster GN Top3alpha PE 2 SV 2
blastp_uniprot_sprot sp|O61660|TOP3_CAEEL 11 455 + 445 Gaps:47 60.08 759 41.89 2e-100 DNA topoisomerase 3 OS Caenorhabditis elegans GN top-3 PE 2 SV 1
blastp_uniprot_sprot sp|O60126|TOP3_SCHPO 10 439 + 430 Gaps:40 72.35 622 39.78 4e-98 DNA topoisomerase 3 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN top3 PE 1 SV 2
blastp_uniprot_sprot sp|Q9Z321|TOP3B_MOUSE 12 439 + 428 Gaps:47 52.32 862 37.92 2e-86 DNA topoisomerase 3-beta-1 OS Mus musculus GN Top3b PE 2 SV 1
blastp_uniprot_sprot sp|O95985|TOP3B_HUMAN 12 439 + 428 Gaps:47 52.32 862 37.92 4e-85 DNA topoisomerase 3-beta-1 OS Homo sapiens GN TOP3B PE 2 SV 1
blastp_uniprot_sprot sp|P13099|TOP3_YEAST 10 438 + 429 Gaps:67 74.70 656 35.10 4e-81 DNA topoisomerase 3 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN TOP3 PE 1 SV 1
blastp_uniprot_sprot sp|O96651|TOP3B_DROME 12 439 + 428 Gaps:40 50.97 875 35.65 7e-72 DNA topoisomerase 3-beta OS Drosophila melanogaster GN Top3beta PE 2 SV 2

17 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 238 333 96 G3DSA:2.70.20.10 none none IPR013825
Gene3D 367 436 70 G3DSA:2.70.20.10 none none IPR013825
PRINTS 393 409 17 PR00417 none Prokaryotic DNA topoisomerase I signature IPR000380
PRINTS 121 134 14 PR00417 none Prokaryotic DNA topoisomerase I signature IPR000380
PRINTS 221 239 19 PR00417 none Prokaryotic DNA topoisomerase I signature IPR000380
ProSiteProfiles 11 157 147 PS50880 none Toprim domain profile. IPR006171
SMART 11 147 137 SM00493 none none IPR006171
SUPERFAMILY 11 435 425 SSF56712 none none IPR023405
PANTHER 6 437 432 PTHR11390:SF23 none none none
SMART 297 460 164 SM00437 none Bacterial DNA topoisomerase I DNA-binding domain IPR003602
Pfam 13 158 146 PF01751 none Toprim domain IPR006171
PANTHER 6 437 432 PTHR11390 none none IPR000380
Gene3D 181 237 57 G3DSA:1.10.460.10 none none IPR013824
Gene3D 11 176 166 G3DSA:3.40.50.140 none none IPR006171
SMART 150 251 102 SM00436 none Bacterial DNA topoisomeraes I ATP-binding domain IPR003601
Pfam 365 434 70 PF01131 none DNA topoisomerase IPR013497
Pfam 175 332 158 PF01131 none DNA topoisomerase IPR013497

0 Localization

2 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2002_QTL13_peak_Bud_burst_3P Qrob_Chr10 10 s_1B1AG7_637 s_1A3A1N_709 19,44 0 49,44 lod 3 5,6
Champenoux_2015_nPriLBD_3P Qrob_Chr10 10 v_15000_157 v_15000_310 15,68 15,9 15,91 lod 2.4 5.5

0 Targeting