GO Term : GO:0001104 RNA polymerase II transcription cofactor activity GO

Namespace  molecular_function Obsolete  false
description  Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal RNAP II transcription machinery.

0 Cross References

1 Ontology

Name
GO

6 Parents

Identifier Name Description
GO:0000989 transcription factor binding transcription factor activity Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
GO:0001104 RNA polymerase II transcription cofactor activity Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal RNAP II transcription machinery.
GO:0003712 transcription cofactor activity Interacting selectively and non-covalently with a regulatory transcription factor and also with the basal transcription machinery in order to modulate transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0000988 protein binding transcription factor activity Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
GO:0001076 RNA polymerase II transcription factor binding transcription factor activity Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

12 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0033990.2 Quercus robur 100.0 egn (M=1) PTHR22795 - SUPPRESSOR OF RNA POLYMERASE B SRB8-RELATED     validated
Qrob_P0155820.2 Quercus robur 100.0 egn (M=2) K15139 - mediator of RNA polymerase II transcription subunit 22     validated
Qrob_P0178300.2 Quercus robur 100.0 egn (M=1) K15151 - mediator of RNA polymerase II transcription subunit 10     validated
Qrob_P0260690.2 Quercus robur 100.0 egn (M=1) K15131 - mediator of RNA polymerase II transcription subunit 11     validated
Qrob_P0261030.2 Quercus robur 100.0 egn (M=1) PTHR13208 - MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4     validated
Qrob_P0455030.2 Quercus robur 100.0 egn (M=2) K15128 - mediator of RNA polymerase II transcription subunit 6     validated
Qrob_P0474750.2 Quercus robur 62.3 egn (M=2) K15148 - mediator of RNA polymerase II transcription subunit 7     validated
Qrob_P0474790.2 Quercus robur 95.1 egn (M=2) K15148 - mediator of RNA polymerase II transcription subunit 7     validated
Qrob_P0484720.2 Quercus robur 100.0 egn (M=1) K15156 - mediator of RNA polymerase II transcription subunit 14     validated
Qrob_P0491730.2 Quercus robur 100.0 egn (M=1) PTHR13104//PTHR13104:SF0 - MED-6-RELATED // SUBFAMILY NOT NAMED     validated
Qrob_P0514150.2 Quercus robur 86.2 egn (M=1) K15153 - mediator of RNA polymerase II transcription subunit 31     validated
Qrob_P0582260.2 Quercus robur 100.0 egn (M=2) K15139 - mediator of RNA polymerase II transcription subunit 22     validated

8 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0003712 GO:0001104
is_a GO:0001076 GO:0001104
is_a GO:0003674 GO:0001104
is_a GO:0000988 GO:0001104
is_a GO:0000989 GO:0001104
is_a GO:0001104 GO:0001105
is_a GO:0001104 GO:0001106
is_a GO:0001104 GO:0001128

6 Synonyms

Name Type
RNA polymerase II transcriptional cofactor activity synonym
RNA polymerase II transcriptional co-regulator synonym
RNA polymerase II transcription mediator activity synonym
GO:0016455 alt_id
TRAP protein synonym
thyroid receptor-associated protein synonym