Protein : Qrob_P0582260.2 Q. robur
Protein Identifier  ? Qrob_P0582260.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=2) K15139 - mediator of RNA polymerase II transcription subunit 22 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 89  
Kegg Orthology  K15139
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0001104 RNA polymerase II transcription cofactor activity Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal RNAP II transcription machinery.
GO:0006357 regulation of transcription from RNA polymerase II promoter Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
GO:0016592 mediator complex A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.

22 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|vvi:100253502 1 87 + 87 none 58.00 150 87.36 8e-47 mediator of RNA polymerase II transcription subunit 22-like
blastp_kegg lcl|pmum:103341246 1 87 + 87 none 54.72 159 86.21 3e-44 mediator of RNA polymerase II transcription subunit 22a-like
blastp_kegg lcl|pper:PRUPE_ppa012665mg 1 87 + 87 none 54.72 159 86.21 3e-44 hypothetical protein
blastp_kegg lcl|tcc:TCM_036681 1 85 + 85 none 57.43 148 85.88 4e-44 Surfeit locus protein 5 subunit 22 of Mediator complex
blastp_kegg lcl|cit:102609763 1 87 + 87 none 58.78 148 83.91 5e-44 mediator of RNA polymerase II transcription subunit 22b-like
blastp_kegg lcl|tcc:TCM_025935 1 86 + 86 none 58.11 148 83.72 1e-43 Surfeit locus protein 5 subunit 22 of Mediator complex
blastp_kegg lcl|cic:CICLE_v10022715mg 1 87 + 87 none 58.78 148 82.76 3e-43 hypothetical protein
blastp_kegg lcl|pop:POPTR_1829s002002 1 85 + 85 none 84.16 101 84.71 2e-42 hypothetical protein
blastp_kegg lcl|pop:POPTR_0008s08020g 1 85 + 85 none 53.80 158 84.71 8e-42 surfeit locus protein 5
blastp_kegg lcl|pxb:103949101 1 87 + 87 none 54.37 160 81.61 4e-41 mediator of RNA polymerase II transcription subunit 22b-like
blastp_uniprot_sprot sp|Q9SA42|MD22A_ARATH 1 83 + 83 none 55.33 150 77.11 8e-40 Mediator of RNA polymerase II transcription subunit 22a OS Arabidopsis thaliana GN MED22A PE 1 SV 1
blastp_uniprot_sprot sp|Q8LCH5|MD22B_ARATH 1 81 + 81 none 52.60 154 77.78 8e-39 Mediator of RNA polymerase II transcription subunit 22b OS Arabidopsis thaliana GN MED22B PE 1 SV 1
blastp_uniprot_sprot sp|Q54XB0|MED22_DICDI 2 79 + 78 none 52.35 149 34.62 2e-10 Putative mediator of RNA polymerase II transcription subunit 22 OS Dictyostelium discoideum GN med22 PE 3 SV 1
blastp_uniprot_sprot sp|A5WUL3|MED22_DANRE 2 79 + 78 none 39.39 198 38.46 7e-10 Mediator of RNA polymerase II transcription subunit 22 OS Danio rerio GN med22 PE 2 SV 1
blastp_uniprot_sprot sp|Q9V439|MED22_DROME 2 78 + 77 none 53.85 143 36.36 1e-09 Mediator of RNA polymerase II transcription subunit 22 OS Drosophila melanogaster GN MED22 PE 1 SV 1
blastp_uniprot_sprot sp|Q178E6|MED22_AEDAE 2 78 + 77 none 55.80 138 32.47 2e-07 Mediator of RNA polymerase II transcription subunit 22 OS Aedes aegypti GN MED22 PE 3 SV 1
blastp_uniprot_sprot sp|Q7QB45|MED22_ANOGA 3 78 + 76 none 55.07 138 32.89 3e-07 Mediator of RNA polymerase II transcription subunit 22 OS Anopheles gambiae GN MED22 PE 3 SV 3
blastp_uniprot_sprot sp|A0JPN6|MED22_RAT 2 65 + 64 none 32.00 200 35.94 1e-06 Mediator of RNA polymerase II transcription subunit 22 OS Rattus norvegicus GN Med22 PE 2 SV 1
blastp_uniprot_sprot sp|Q62276|MED22_MOUSE 2 65 + 64 none 32.00 200 35.94 1e-06 Mediator of RNA polymerase II transcription subunit 22 OS Mus musculus GN Med22 PE 2 SV 2
blastp_uniprot_sprot sp|Q15528|MED22_HUMAN 2 63 + 62 none 31.00 200 37.10 1e-06 Mediator of RNA polymerase II transcription subunit 22 OS Homo sapiens GN MED22 PE 1 SV 2
rpsblast_cdd gnl|CDD|203401 1 70 + 70 none 64.81 108 37.14 3e-14 pfam06179 Med22 Surfeit locus protein 5 subunit 22 of Mediator complex. This family consists of several eukaryotic Surfeit locus protein 5 (SURF5) sequences. The human Surfeit locus has been mapped on chromosome 9q34.1. The locus includes six tightly clustered housekeeping genes (Surf1-6) and the gene organisation is similar in human mouse and chicken Surfeit locus. The Med22 subunit of Mediator complex is part of the essential core head region.
rpsblast_kog gnl|CDD|38514 1 83 + 83 none 56.08 148 46.99 3e-20 KOG3304 KOG3304 KOG3304 Surfeit family protein 5 [General function prediction only].

2 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 1 71 71 PF06179 none Surfeit locus protein 5 subunit 22 of Mediator complex IPR009332
PANTHER 1 88 88 PTHR12434 none none IPR009332

0 Localization

0 Qtllist

0 Targeting