Protein : Qrob_P0261030.2 Q. robur
Protein Identifier  ? Qrob_P0261030.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) PTHR13208 - MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 411  
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0001104 RNA polymerase II transcription cofactor activity Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal RNAP II transcription machinery.
GO:0006357 regulation of transcription from RNA polymerase II promoter Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
GO:0016592 mediator complex A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.

13 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|cic:CICLE_v10011831mg 1 409 + 409 Gaps:13 98.57 420 72.46 0.0 hypothetical protein
blastp_kegg lcl|cmo:103491209 1 410 + 410 Gaps:32 98.77 407 73.13 8e-180 mediator of RNA polymerase II transcription subunit 4
blastp_kegg lcl|csv:101202914 1 410 + 410 Gaps:29 98.76 404 73.68 6e-179 mediator of RNA polymerase II transcription subunit 4-like
blastp_kegg lcl|cit:102619807 1 409 + 409 Gaps:13 98.57 420 72.46 2e-177 mediator of RNA polymerase II transcription subunit 4-like
blastp_kegg lcl|tcc:TCM_022075 1 390 + 390 Gaps:14 94.00 417 71.68 1e-176 Hydroxyproline-rich glycoprotein family protein
blastp_kegg lcl|pmum:103328596 1 410 + 410 Gaps:33 98.74 396 71.36 2e-174 mediator of RNA polymerase II transcription subunit 4-like
blastp_kegg lcl|vvi:100249946 1 410 + 410 Gaps:24 98.07 414 73.15 5e-174 uncharacterized LOC100249946
blastp_kegg lcl|mtr:MTR_8g075790 1 389 + 389 Gaps:40 93.78 402 70.82 2e-167 hypothetical protein
blastp_kegg lcl|pper:PRUPE_ppa006763mg 1 410 + 410 Gaps:33 98.74 396 71.10 4e-158 hypothetical protein
blastp_kegg lcl|pmum:103332131 1 410 + 410 Gaps:35 98.74 396 71.36 3e-156 mediator of RNA polymerase II transcription subunit 4-like
blastp_uniprot_sprot sp|Q9LZ00|MED4_ARATH 1 391 + 391 Gaps:22 94.60 426 64.52 5e-135 Mediator of RNA polymerase II transcription subunit 4 OS Arabidopsis thaliana GN MED4 PE 1 SV 1
blastp_uniprot_sprot sp|Q54D00|MED4_DICDI 147 279 + 133 Gaps:18 42.86 343 33.33 1e-06 Putative mediator of RNA polymerase II transcription subunit 4 OS Dictyostelium discoideum GN med4 PE 3 SV 1
rpsblast_cdd gnl|CDD|192445 121 302 + 182 Gaps:35 94.89 176 28.14 3e-23 pfam10018 Med4 Vitamin-D-receptor interacting Mediator subunit 4. Members of this family function as part of the Mediator (Med) complex which links DNA-bound transcriptional regulators and the general transcription machinery particularly the RNA polymerase II enzyme. They play a role in basal transcription by mediating activation or repression according to the specific complement of transcriptional regulators bound to the promoter.

5 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 40 197 158 PTHR13208:SF2 none none none
PANTHER 214 410 197 PTHR13208:SF2 none none none
PANTHER 40 197 158 PTHR13208 none none none
PANTHER 214 410 197 PTHR13208 none none none
Pfam 122 290 169 PF10018 none Vitamin-D-receptor interacting Mediator subunit 4 IPR019258

0 Localization

6 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nEpis*_A4 Qrob_Chr07 7 v_12400_446 s_1BPEBU_1211 6,93 0 15,13 lod 4,7411 11
Bourran2_2014_nLBD_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 37,41 9,8 50,1 lod 1,9524 4,1
Bourran2_2014_nPriBD_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,51 3,36 51,86 lod 1,6747 3,9
Bourran2_2014_nSecLBD_A4 Qrob_Chr07 7 v_8327_222 s_1A4WGY_363 16,04 0 44,69 lod 2,6373 6,5
Bourran2_2014_vEpiBC_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 37,55 14,41 50,01 lod 1,7882 4,8
Champenoux_2015_nEpis_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,53 25,47 27,72 lod 4.4 8.9

0 Targeting