Protein : Qrob_P0260690.2 Q. robur
Protein Identifier  ? Qrob_P0260690.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) K15131 - mediator of RNA polymerase II transcription subunit 11 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 116  
Kegg Orthology  K15131
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0001104 RNA polymerase II transcription cofactor activity Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal RNAP II transcription machinery.
GO:0006357 regulation of transcription from RNA polymerase II promoter Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
GO:0016592 mediator complex A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.

12 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|sly:101262909 1 115 + 115 none 94.26 122 88.70 6e-70 mediator of RNA polymerase II transcription subunit 11-like
blastp_kegg lcl|pmum:103335475 1 115 + 115 none 97.46 118 84.35 5e-69 mediator of RNA polymerase II transcription subunit 11
blastp_kegg lcl|pper:PRUPE_ppa013516mg 1 115 + 115 none 97.46 118 84.35 5e-69 hypothetical protein
blastp_kegg lcl|sot:102599143 1 115 + 115 none 94.26 122 86.96 7e-69 mediator of RNA polymerase II transcription subunit 11-like
blastp_kegg lcl|pxb:103937300 1 115 + 115 none 100.00 115 85.22 2e-68 mediator of RNA polymerase II transcription subunit 11-like
blastp_kegg lcl|pxb:103968001 1 115 + 115 none 100.00 115 85.22 2e-68 mediator of RNA polymerase II transcription subunit 11-like
blastp_kegg lcl|pxb:103967995 1 115 + 115 none 100.00 115 85.22 2e-68 mediator of RNA polymerase II transcription subunit 11-like
blastp_kegg lcl|tcc:TCM_030340 1 113 + 113 none 93.39 121 86.73 6e-68 Mediator of RNA polymerase II transcription subunit 11
blastp_kegg lcl|pper:PRUPE_ppa013517mg 1 115 + 115 none 97.46 118 83.48 1e-67 hypothetical protein
blastp_kegg lcl|cam:101503401 1 114 + 114 none 99.13 115 84.21 5e-67 mediator of RNA polymerase II transcription subunit 11-like
blastp_uniprot_sprot sp|Q6ID77|MED11_ARATH 1 114 + 114 none 99.13 115 71.05 2e-58 Mediator of RNA polymerase II transcription subunit 11 OS Arabidopsis thaliana GN MED11 PE 1 SV 1
rpsblast_cdd gnl|CDD|204431 6 113 + 108 Gaps:5 100.00 113 26.55 1e-16 pfam10280 Med11 Mediator complex protein. Mediator is a large modular protein complex that is conserved from yeast to human and conveys regulatory signals from DNA-binding transcription factors to RNA polymerase II. Not only are the polypeptides conserved but the structural organisation is also largely conserved. One or two subunits are either fungal or vertebral specific but Med11 is one of the subunits that is conserved from fungi to humans. Med11 appears to be necessary for the full and successful assembly of the core head sub-region.

2 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 1 111 111 PTHR22890 none none none
Pfam 7 112 106 PF10280 none Mediator complex protein IPR019404

0 Localization

0 Qtllist

0 Targeting