Protein : Qrob_P0178300.2 Q. robur
Protein Identifier  ? Qrob_P0178300.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) K15151 - mediator of RNA polymerase II transcription subunit 10 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 191  
Kegg Orthology  K15151
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0001104 RNA polymerase II transcription cofactor activity Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal RNAP II transcription machinery.
GO:0006357 regulation of transcription from RNA polymerase II promoter Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
GO:0016592 mediator complex A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.

22 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|rcu:RCOM_0085590 1 190 + 190 Gaps:3 100.00 187 85.03 1e-108 nut2 putative
blastp_kegg lcl|pmum:103337842 1 189 + 189 none 99.47 190 79.89 9e-108 mediator of RNA polymerase II transcription subunit 10b
blastp_kegg lcl|cic:CICLE_v10022441mg 8 190 + 183 Gaps:1 97.85 186 83.52 1e-107 hypothetical protein
blastp_kegg lcl|pper:PRUPE_ppa012016mg 1 189 + 189 Gaps:5 99.47 187 82.80 3e-107 hypothetical protein
blastp_kegg lcl|pper:PRUPE_ppa011942mg 1 189 + 189 none 99.47 190 78.84 4e-107 hypothetical protein
blastp_kegg lcl|cit:102608713 8 190 + 183 Gaps:1 97.85 186 82.97 1e-106 mediator of RNA polymerase II transcription subunit 10b-like
blastp_kegg lcl|pop:POPTR_0001s11370g 1 190 + 190 none 100.00 190 82.63 1e-106 POPTRDRAFT_815000 RNA polymerase II mediator complex family protein
blastp_kegg lcl|pmum:103333669 1 189 + 189 Gaps:5 99.47 187 82.26 2e-106 mediator of RNA polymerase II transcription subunit 10b-like
blastp_kegg lcl|tcc:TCM_015646 1 190 + 190 none 100.00 190 82.11 1e-105 Mediator complex subunit Med10 isoform 1
blastp_kegg lcl|vvi:100263293 1 190 + 190 Gaps:6 100.00 194 79.90 9e-105 mediator of RNA polymerase II transcription subunit 10-like
blastp_uniprot_sprot sp|F4HPA7|MD10B_ARATH 1 190 + 190 Gaps:3 100.00 189 73.54 4e-95 Mediator of RNA polymerase II transcription subunit 10b OS Arabidopsis thaliana GN MED10B PE 1 SV 1
blastp_uniprot_sprot sp|Q9FHZ2|MD10A_ARATH 1 190 + 190 Gaps:6 100.00 186 70.97 1e-85 Mediator of RNA polymerase II transcription subunit 10a OS Arabidopsis thaliana GN MED10A PE 1 SV 1
blastp_uniprot_sprot sp|Q16G71|MED10_AEDAE 40 163 + 124 none 95.38 130 34.68 7e-22 Mediator of RNA polymerase II transcription subunit 10 OS Aedes aegypti GN MED10 PE 3 SV 1
blastp_uniprot_sprot sp|Q7Q5R5|MED10_ANOGA 36 163 + 128 Gaps:3 96.15 130 36.00 2e-21 Mediator of RNA polymerase II transcription subunit 10 OS Anopheles gambiae GN MED10 PE 3 SV 2
blastp_uniprot_sprot sp|Q9CXU0|MED10_MOUSE 38 163 + 126 Gaps:1 94.07 135 33.07 7e-20 Mediator of RNA polymerase II transcription subunit 10 OS Mus musculus GN Med10 PE 1 SV 1
blastp_uniprot_sprot sp|Q5R6P5|MED10_PONAB 38 163 + 126 Gaps:1 94.07 135 33.07 1e-19 Mediator of RNA polymerase II transcription subunit 10 OS Pongo abelii GN MED10 PE 2 SV 1
blastp_uniprot_sprot sp|Q9BTT4|MED10_HUMAN 38 163 + 126 Gaps:1 94.07 135 33.07 1e-19 Mediator of RNA polymerase II transcription subunit 10 OS Homo sapiens GN MED10 PE 1 SV 1
blastp_uniprot_sprot sp|Q3ZCF2|MED10_BOVIN 38 163 + 126 Gaps:1 94.07 135 33.07 1e-19 Mediator of RNA polymerase II transcription subunit 10 OS Bos taurus GN MED10 PE 2 SV 1
blastp_uniprot_sprot sp|Q6DJ25|MED10_XENTR 33 163 + 131 Gaps:8 92.59 135 35.20 2e-18 Mediator of RNA polymerase II transcription subunit 10 OS Xenopus tropicalis GN med10 PE 2 SV 1
blastp_uniprot_sprot sp|Q4R6W4|MED10_MACFA 38 163 + 126 Gaps:1 94.07 135 32.28 2e-18 Mediator of RNA polymerase II transcription subunit 10 OS Macaca fascicularis GN MED10 PE 2 SV 1
rpsblast_cdd gnl|CDD|150423 43 161 + 119 Gaps:1 100.00 120 41.67 3e-37 pfam09748 Med10 Transcription factor subunit Med10 of Mediator complex. Med10 is one of the protein subunits of the Mediator complex tethered to Rgr1 protein. The Mediator complex is required for the transcription of most RNA polymerase II (Pol II)-transcribed genes. Med10 specifically mediates basal-level HIS4 transcription via Gcn4 and additionally there is a putative requirement for Med10 in Bas2-mediated transcription. Med10 is part of the middle region of Mediator.
rpsblast_kog gnl|CDD|38256 27 172 + 146 Gaps:1 100.00 147 48.98 1e-42 KOG3046 KOG3046 KOG3046 Transcription factor subunit of SRB subcomplex of RNA polymerase II [Transcription].

2 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 45 161 117 PF09748 none Transcription factor subunit Med10 of Mediator complex IPR019145
PANTHER 47 187 141 PTHR13345 none none none

0 Localization

19 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran1_2003_QTL2_peak_Bud_burst_A4 Qrob_Chr02 2 s_1B0H8U_259 s_1CB1VL_554 17 0 87 lod 3,3 8,7
Bourran2_2004_QTL9_peak_Bud_burst_3P Qrob_Chr02 2 s_1C34E9_788 v_12238_322 50 25 75 lod 4,4 10,1
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL2_d13Cf Qrob_Chr02 2 s_1AQA4Z_1644 s_1AK5QX_947 53.67 14,01 79,68 lod 5.6594 0.03
Bourran1_2004_QTL2_peak_Bud_burst_3P Qrob_Chr02 2 s_1AW12F_382 s_1A77MR_223 42 6 64 lod 3,6 9,6
Bourran2_2002_QTL7_peak_Bud_burst_3P Qrob_Chr02 2 s_1ANG6_1446 v_11270_161 40 29 52 lod 8,1 16
Bourran2_2002_QTL9_peak_Bud_burst_A4 Qrob_Chr02 2 s_1BFNDA_375 s_1A3VA1_2139 32,5 17 62 lod 3,1 4,2
Bourran2_2003_QTL8_peak_Bud_burst_3P Qrob_Chr02 2 s_1ANG6_1446 v_11270_161 40 0 72 lod 4,4 9,9
Bourran2_2014_nP_A4 Qrob_Chr11 11 s_1B58GB_1413 s_1A5BYY_1671 11,15 0 42,38 lod 1,8913 4,5
Bourran2_2015_nP_A4 Qrob_Chr02 2 s_1A0FUE_1868 s_1A1UAI_500 20,64 20,47 21,36 lod 5.8 10.9
Bourran2_2015_nPriLBD_A4 Qrob_Chr02 2 s_1CP5DI_1183 s_1A63ZX_1277 24,87 24,63 26,18 lod 3.8 7
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL6_d13Cf Qrob_Chr02 2 s_1AEP21_172 v_6048_204 46.33 22,5 65,23 lod 4.972 0.03
Bourran2_2015_nEpis_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 34,94 34,88 37,45 lod 3.1 7
Bourran2_2015_nSecLBD_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 35,81 34,88 37,45 lod 4.4 10.4
Bourran1_2003_QTL1_peak_Bud_burst_3P Qrob_Chr02 2 s_1AR8KI_1183 s_1B0QB1_473 22 6 41 lod 4,2 11,5
Bourran1_2004_QTL3_peak_Bud_burst_A4 Qrob_Chr02 2 s_1B0H8U_259 s_1CB1VL_554 17 0 46 lod 2,9 6,4
Bourran2_2015_nEpiBC_A4 Qrob_Chr07 7 s_1DP9TW_798 v_8128_173 22,61 22,14 22,73 lod 3.1 8.5
Champenoux_2015_nEpis_A4 Qrob_Chr02 2 s_1BAGIZ_823 s_1BN4CB_644 23,06 23,06 23,06 lod 4.9 11
Champenoux_2015_nP_A4 Qrob_Chr02 2 s_1BN4CB_644 v_508_128 23,76 23,06 24,51 lod 2.8 6.2
Champenoux_2015_nPriLBD_A4 Qrob_Chr02 2 s_1CP5DI_1183 s_1A63ZX_1277 25,35 24,63 26,18 lod 4.0 8.7

0 Targeting