Protein : Qrob_P0474790.2 Q. robur
Protein Identifier  ? Qrob_P0474790.2 Organism . Name  Quercus robur
Score  95.1 Score Type  egn
Protein Description  (M=2) K15148 - mediator of RNA polymerase II transcription subunit 7 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 157  
Kegg Orthology  K15148
Paste the following link
Lists
This Protein isn't in any lists. Upload a list.

Sequence Feature Displayer

Protein Sequence Displayer

J Browse Displayer

0 Synonyms

3 GO Terms

Identifier Name Description
GO:0001104 RNA polymerase II transcription cofactor activity Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal RNAP II transcription machinery.
GO:0006357 regulation of transcription from RNA polymerase II promoter Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
GO:0016592 mediator complex A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.

25 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|sot:102597158 1 149 + 149 none 88.69 168 93.29 2e-91 mediator of RNA polymerase II transcription subunit 7a-like
blastp_kegg lcl|sly:101262307 1 149 + 149 none 88.69 168 93.29 2e-91 mediator of RNA polymerase II transcription subunit 7b-like
blastp_kegg lcl|tcc:TCM_025030 1 150 + 150 none 86.71 173 94.00 4e-89 Mediator of RNA polymerase II transcription subunit 7 isoform 1
blastp_kegg lcl|cmo:103486732 1 149 + 149 none 88.69 168 91.28 7e-87 mediator of RNA polymerase II transcription subunit 7a-like
blastp_kegg lcl|csv:101216221 1 149 + 149 none 88.69 168 91.28 7e-87 mediator of RNA polymerase II transcription subunit 7b-like
blastp_kegg lcl|cic:CICLE_v10012936mg 1 149 + 149 none 88.69 168 94.63 9e-86 hypothetical protein
blastp_kegg lcl|fve:101295249 1 149 + 149 none 85.14 175 93.29 2e-85 mediator of RNA polymerase II transcription subunit 7b-like
blastp_kegg lcl|pvu:PHAVU_010G156700g 1 148 + 148 none 88.10 168 89.86 7e-85 hypothetical protein
blastp_kegg lcl|cit:102624512 1 149 + 149 none 88.69 168 93.29 3e-84 mediator of RNA polymerase II transcription subunit 7a-like
blastp_kegg lcl|pmum:103339602 1 149 + 149 none 85.14 175 91.95 3e-84 mediator of RNA polymerase II transcription subunit 7a-like
blastp_pdb 1ykh_A 87 149 + 63 none 58.33 108 42.86 3e-10 mol:protein length:108 RNA polymerase II mediator complex protein ME
blastp_pdb 1yke_C 87 149 + 63 none 58.33 108 42.86 3e-10 mol:protein length:108 RNA polymerase II mediator complex protein ME
blastp_pdb 1yke_A 87 149 + 63 none 58.33 108 42.86 3e-10 mol:protein length:108 RNA polymerase II mediator complex protein ME
blastp_uniprot_sprot sp|Q9LZD7|MED7B_ARATH 1 149 + 149 none 88.69 168 85.91 6e-82 Mediator of RNA polymerase II transcription subunit 7b OS Arabidopsis thaliana GN MED7B PE 1 SV 1
blastp_uniprot_sprot sp|Q9LYW3|MED7A_ARATH 1 149 + 149 none 88.69 168 86.58 4e-77 Mediator of RNA polymerase II transcription subunit 7a OS Arabidopsis thaliana GN MED7A PE 1 SV 1
blastp_uniprot_sprot sp|Q17MI0|MED7_AEDAE 1 150 + 150 Gaps:6 69.41 219 40.79 1e-31 Mediator of RNA polymerase II transcription subunit 7 OS Aedes aegypti GN MED7 PE 3 SV 1
blastp_uniprot_sprot sp|Q55DQ5|MED7_DICDI 33 149 + 117 Gaps:1 33.62 345 48.28 3e-31 Putative mediator of RNA polymerase II transcription subunit 7 OS Dictyostelium discoideum GN med7 PE 3 SV 1
blastp_uniprot_sprot sp|Q7PR68|MED7_ANOGA 8 150 + 143 Gaps:8 64.38 219 43.26 2e-28 Mediator of RNA polymerase II transcription subunit 7 OS Anopheles gambiae GN MED7 PE 3 SV 2
blastp_uniprot_sprot sp|Q2F7Z4|MED7_PIG 2 150 + 149 Gaps:5 64.38 233 38.00 3e-27 Mediator of RNA polymerase II transcription subunit 7 OS Sus scrofa GN MED7 PE 2 SV 2
blastp_uniprot_sprot sp|O43513|MED7_HUMAN 2 150 + 149 Gaps:5 64.38 233 38.00 3e-27 Mediator of RNA polymerase II transcription subunit 7 OS Homo sapiens GN MED7 PE 1 SV 1
blastp_uniprot_sprot sp|Q9CZB6|MED7_MOUSE 2 150 + 149 Gaps:5 64.38 233 38.00 3e-27 Mediator of RNA polymerase II transcription subunit 7 OS Mus musculus GN Med7 PE 2 SV 2
blastp_uniprot_sprot sp|Q3T123|MED7_BOVIN 2 150 + 149 Gaps:5 64.38 233 38.00 3e-27 Mediator of RNA polymerase II transcription subunit 7 OS Bos taurus GN MED7 PE 2 SV 1
blastp_uniprot_sprot sp|Q7ZV35|MED7_DANRE 2 150 + 149 Gaps:5 62.24 241 36.67 1e-26 Mediator of RNA polymerase II transcription subunit 7 OS Danio rerio GN med7 PE 2 SV 1
rpsblast_cdd gnl|CDD|147892 1 150 + 150 Gaps:2 94.41 161 44.74 3e-48 pfam05983 Med7 MED7 protein. This family consists of several eukaryotic proteins which are homologues of the yeast MED7 protein. Activation of gene transcription in metazoans is a multi-step process that is triggered by factors that recognise transcriptional enhancer sites in DNA. These factors work with co-activators such as MED7 to direct transcriptional initiation by the RNA polymerase II apparatus.
rpsblast_kog gnl|CDD|35790 1 150 + 150 none 67.26 223 56.00 2e-52 KOG0570 KOG0570 KOG0570 Transcriptional coactivator [Transcription].

4 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 6 150 145 PTHR21428 none none IPR009244
SUPERFAMILY 67 150 84 SSF140718 none none none
PANTHER 6 150 145 PTHR21428:SF11 none none none
Pfam 3 149 147 PF05983 none MED7 protein IPR009244

0 Localization

0 Qtllist

0 Targeting