Protein : Qrob_P0491730.2 Q. robur
Protein Identifier  ? Qrob_P0491730.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) PTHR13104//PTHR13104:SF0 - MED-6-RELATED // SUBFAMILY NOT NAMED Gene Prediction Quality  validated
Protein length 

Sequence

Length: 170  
Kegg Orthology  K15128
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0001104 RNA polymerase II transcription cofactor activity Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal RNAP II transcription machinery.
GO:0006357 regulation of transcription from RNA polymerase II promoter Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
GO:0016592 mediator complex A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.

26 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|rcu:RCOM_1486710 1 169 + 169 none 67.33 251 84.02 2e-88 RNA polymerase II mediator complex subunit putative
blastp_kegg lcl|vvi:100253150 1 169 + 169 Gaps:1 65.89 258 82.94 6e-85 putative mediator of RNA polymerase II transcription subunit 6-like
blastp_kegg lcl|tcc:TCM_028940 1 169 + 169 Gaps:1 66.15 257 81.18 2e-84 RNA polymerase transcriptional regulation mediator-related isoform 1
blastp_kegg lcl|pper:PRUPE_ppa010369mg 1 169 + 169 Gaps:1 67.46 252 81.18 1e-83 hypothetical protein
blastp_kegg lcl|pmum:103342864 1 169 + 169 Gaps:1 67.46 252 81.18 2e-83 mediator of RNA polymerase II transcription subunit 6
blastp_kegg lcl|pvu:PHAVU_010G143300g 1 169 + 169 Gaps:1 68.83 247 80.00 6e-83 hypothetical protein
blastp_kegg lcl|gmx:100792248 1 169 + 169 Gaps:4 68.65 252 78.03 1e-82 mediator of RNA polymerase II transcription subunit 6-like
blastp_kegg lcl|csv:101229093 1 169 + 169 Gaps:2 73.89 226 82.63 2e-82 mediator of RNA polymerase II transcription subunit 6-like
blastp_kegg lcl|cmo:103489986 1 169 + 169 Gaps:2 65.49 255 83.23 2e-81 mediator of RNA polymerase II transcription subunit 6
blastp_kegg lcl|pop:POPTR_0017s03500g 1 169 + 169 Gaps:1 65.64 259 79.41 6e-81 RNA polymerase transcriptional regulation mediator-related family protein
blastp_pdb 3rj1_U 1 68 + 68 Gaps:10 25.76 295 36.84 1e-09 mol:protein length:295 Mediator of RNA polymerase II transcription s
blastp_pdb 3rj1_N 1 68 + 68 Gaps:10 25.76 295 36.84 1e-09 mol:protein length:295 Mediator of RNA polymerase II transcription s
blastp_pdb 3rj1_G 1 68 + 68 Gaps:10 25.76 295 36.84 1e-09 mol:protein length:295 Mediator of RNA polymerase II transcription s
blastp_uniprot_sprot sp|F4IXJ7|MED6_ARATH 1 169 + 169 Gaps:43 70.47 298 56.19 5e-58 Mediator of RNA polymerase II transcription subunit 6 OS Arabidopsis thaliana GN MED6 PE 1 SV 1
blastp_uniprot_sprot sp|Q7Q107|MED6_ANOGA 1 140 + 140 Gaps:15 58.05 267 34.84 5e-19 Mediator of RNA polymerase II transcription subunit 6 OS Anopheles gambiae GN MED6 PE 3 SV 3
blastp_uniprot_sprot sp|Q8MSX2|MED6_DROME 1 153 + 153 Gaps:19 67.47 249 33.93 2e-18 Mediator of RNA polymerase II transcription subunit 6 OS Drosophila melanogaster GN MED6 PE 1 SV 1
blastp_uniprot_sprot sp|Q3SZY9|MED6_BOVIN 1 154 + 154 Gaps:29 71.95 246 33.90 4e-16 Mediator of RNA polymerase II transcription subunit 6 OS Bos taurus GN MED6 PE 2 SV 1
blastp_uniprot_sprot sp|Q921D4|MED6_MOUSE 1 142 + 142 Gaps:9 61.38 246 34.44 6e-16 Mediator of RNA polymerase II transcription subunit 6 OS Mus musculus GN Med6 PE 2 SV 2
blastp_uniprot_sprot sp|O75586|MED6_HUMAN 1 119 + 119 Gaps:9 52.03 246 35.16 2e-15 Mediator of RNA polymerase II transcription subunit 6 OS Homo sapiens GN MED6 PE 1 SV 2
blastp_uniprot_sprot sp|Q5RD94|MED6_PONAB 1 119 + 119 Gaps:9 52.03 246 35.16 2e-15 Mediator of RNA polymerase II transcription subunit 6 OS Pongo abelii GN MED6 PE 2 SV 1
blastp_uniprot_sprot sp|Q6IQ63|MED6_DANRE 1 120 + 120 Gaps:9 50.79 254 34.11 3e-15 Mediator of RNA polymerase II transcription subunit 6 OS Danio rerio GN med6 PE 2 SV 1
blastp_uniprot_sprot sp|Q54PN3|MED6_DICDI 1 128 + 128 Gaps:6 50.19 267 36.57 3e-15 Putative mediator of RNA polymerase II transcription subunit 6 OS Dictyostelium discoideum GN med6 PE 3 SV 1
blastp_uniprot_sprot sp|Q6CTT6|MED6_KLULA 1 78 + 78 Gaps:4 27.61 268 41.89 2e-13 Mediator of RNA polymerase II transcription subunit 6 OS Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) GN MED6 PE 3 SV 1
rpsblast_cdd gnl|CDD|203126 1 73 + 73 none 54.48 134 50.68 7e-25 pfam04934 Med6 MED6 mediator sub complex component. Component of RNA polymerase II holoenzyme and mediator sub complex.
rpsblast_cdd gnl|CDD|34700 1 69 + 69 none 32.86 210 30.43 2e-10 COG5097 MED6 RNA polymerase II transcriptional regulation mediator [Transcription].
rpsblast_kog gnl|CDD|38379 1 76 + 76 none 36.54 208 43.42 8e-16 KOG3169 KOG3169 KOG3169 RNA polymerase II transcriptional regulation mediator [Transcription].

3 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 1 169 169 PTHR13104:SF0 none none none
Pfam 1 72 72 PF04934 none MED6 mediator sub complex component IPR007018
PANTHER 1 169 169 PTHR13104 none none IPR007018

0 Localization

2 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2014_rEpiBC_3P Qrob_Chr05 5 s_2GDU0O_517 s_1BT8O3_239 25,81 0 55,45 lod 2,2101 5,5

0 Targeting