GO Term : GO:0005730 nucleolus GO

Namespace  cellular_component Obsolete  false
description  A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

0 Cross References

1 Ontology

Name
GO

20 Parents

Identifier Name Description
GO:0005634 nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005730 nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
GO:0043231 intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0044424 intracellular part Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0044428 nuclear part Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.
GO:0044422 organelle part Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
GO:0044446 intracellular organelle part A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
GO:0043226 organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GO:0043227 membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0043229 intracellular organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0043233 organelle lumen The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.
GO:0031981 nuclear lumen The volume enclosed by the nuclear inner membrane.
GO:0070013 intracellular organelle lumen An organelle lumen that is part of an intracellular organelle.
GO:0031974 membrane-enclosed lumen The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.
GO:0043228 non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
GO:0043232 intracellular non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

11 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0133720.2 Quercus robur 100.0 egn (M=1) K11129 - H/ACA ribonucleoprotein complex subunit 2     validated
Qrob_P0290660.2 Quercus robur 6.3 egn (M=1) KOG0263//KOG0266//KOG0271//KOG0272//KOG0274//KOG0296//KOG0310//KOG0319//KOG2495//KOG4378 - Transcription initiation factor TFIID subunit TAF5 (also component of histone acetyltransferase SAGA) [Transcription]. // WD40 repeat-containing protein [General function prediction only]. // Notchless-like WD40 repeat-containing protein [Function unknown]. // U4/U6 small nuclear ribonucleoprotein Prp4 (contains WD40 repeats) [RNA processing and modification]. // Cdc4 and related F-box and WD-40 proteins [General function prediction only]. // Angio-associated migratory cell protein (contains WD40 repeats) [Function unknown]. // Conserved WD40 repeat-containing protein [Function unknown]. // WD40-repeat-containing subunit of the 18S rRNA processing complex [RNA processing and modification]. // NADH-dehydrogenase (ubiquinone) [Energy production and conversion]. // Nuclear protein COP1 [Signal transduction mechanisms].     validated
Qrob_P0290760.2 Quercus robur 0.0 egn (M=2) KOG0263//KOG0266//KOG0271//KOG0272//KOG0274//KOG0276//KOG0284//KOG0305//KOG0310//KOG0319 - Transcription initiation factor TFIID subunit TAF5 (also component of histone acetyltransferase SAGA) [Transcription]. // WD40 repeat-containing protein [General function prediction only]. // Notchless-like WD40 repeat-containing protein [Function unknown]. // U4/U6 small nuclear ribonucleoprotein Prp4 (contains WD40 repeats) [RNA processing and modification]. // Cdc4 and related F-box and WD-40 proteins [General function prediction only]. // Vesicle coat complex COPI beta' subunit [Intracellular trafficking secretion and vesicular transport]. // Polyadenylation factor I complex subunit PFS2 [RNA processing and modification]. // Anaphase promoting complex Cdc20 Cdh1 and Ama1 subunits [Cell cycle control cell division chromosome partitioning Posttranslational modification protein turnover chaperones]. // Conserved WD40 repeat-containing protein [Function unknown]. // WD40-repeat-containing subunit of the 18S rRNA processing complex [RNA processing and modification].     validated
Qrob_P0290810.2 Quercus robur 0.0 egn (M=6) K14549 - U3 small nucleolar RNA-associated protein 15     validated
Qrob_P0290830.2 Quercus robur 0.0 egn (M=1) KOG0263//KOG0266//KOG0271//KOG0272//KOG0274//KOG0282//KOG0284//KOG0285//KOG0310//KOG0319 - Transcription initiation factor TFIID subunit TAF5 (also component of histone acetyltransferase SAGA) [Transcription]. // WD40 repeat-containing protein [General function prediction only]. // Notchless-like WD40 repeat-containing protein [Function unknown]. // U4/U6 small nuclear ribonucleoprotein Prp4 (contains WD40 repeats) [RNA processing and modification]. // Cdc4 and related F-box and WD-40 proteins [General function prediction only]. // mRNA splicing factor [Function unknown]. // Polyadenylation factor I complex subunit PFS2 [RNA processing and modification]. // Pleiotropic regulator 1 [RNA processing and modification]. // Conserved WD40 repeat-containing protein [Function unknown]. // WD40-repeat-containing subunit of the 18S rRNA processing complex [RNA processing and modification].     validated
Qrob_P0294600.2 Quercus robur 90.0 egn (M=1) K12845 - U4/U6 small nuclear ribonucleoprotein SNU13     validated
Qrob_P0297860.2 Quercus robur 100.0 egn (M=2) KOG0263//KOG0266//KOG0271//KOG0272//KOG0274//KOG0276//KOG0284//KOG0305//KOG0310//KOG0319 - Transcription initiation factor TFIID subunit TAF5 (also component of histone acetyltransferase SAGA) [Transcription]. // WD40 repeat-containing protein [General function prediction only]. // Notchless-like WD40 repeat-containing protein [Function unknown]. // U4/U6 small nuclear ribonucleoprotein Prp4 (contains WD40 repeats) [RNA processing and modification]. // Cdc4 and related F-box and WD-40 proteins [General function prediction only]. // Vesicle coat complex COPI beta' subunit [Intracellular trafficking secretion and vesicular transport]. // Polyadenylation factor I complex subunit PFS2 [RNA processing and modification]. // Anaphase promoting complex Cdc20 Cdh1 and Ama1 subunits [Cell cycle control cell division chromosome partitioning Posttranslational modification protein turnover chaperones]. // Conserved WD40 repeat-containing protein [Function unknown]. // WD40-repeat-containing subunit of the 18S rRNA processing complex [RNA processing and modification].     validated
Qrob_P0335750.2 Quercus robur 100.0 egn (M=1) K14537 - nuclear GTP-binding protein     validated
Qrob_P0347410.2 Quercus robur 99.0 egn (M=3) K06943 - nucleolar GTP-binding protein     validated
Qrob_P0689980.2 Quercus robur 54.4 egn (M=3) K06943 - nucleolar GTP-binding protein     validated
Qrob_P0766940.2 Quercus robur 100.0 egn (M=1) K14843 - pescadillo     validated

50 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0005730 GO:0000120
part of GO:0005730 GO:0000500
part of GO:0005730 GO:0001650
part of GO:0005730 GO:0001651
part of GO:0005730 GO:0001652
part of GO:0005730 GO:0005655
part of GO:0005730 GO:0005668
part of GO:0031981 GO:0005730
is_a GO:0043232 GO:0005730
is_a GO:0044428 GO:0005730
part of GO:0031974 GO:0005730
part of GO:0005575 GO:0005730
part of GO:0044428 GO:0005730
part of GO:0044464 GO:0005730
is_a GO:0044424 GO:0005730
part of GO:0044422 GO:0005730
part of GO:0044446 GO:0005730
part of GO:0043231 GO:0005730
part of GO:0044424 GO:0005730
is_a GO:0044446 GO:0005730
part of GO:0043233 GO:0005730
part of GO:0043227 GO:0005730
part of GO:0043226 GO:0005730
is_a GO:0005575 GO:0005730
is_a GO:0044464 GO:0005730
part of GO:0005634 GO:0005730
is_a GO:0043226 GO:0005730
part of GO:0005623 GO:0005730
part of GO:0043229 GO:0005730
is_a GO:0044422 GO:0005730

0 Synonyms