Protein : Qrob_P0347410.2 Q. robur
Protein Identifier  ? Qrob_P0347410.2 Organism . Name  Quercus robur
Score  99.0 Score Type  egn
Protein Description  (M=3) K06943 - nucleolar GTP-binding protein Gene Prediction Quality  validated
Protein length 

Sequence

Length: 672  
Kegg Orthology  K06943
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0 Synonyms

2 GO Terms

Identifier Name Description
GO:0005525 GTP binding Interacting selectively and non-covalently with GTP, guanosine triphosphate.
GO:0005730 nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

35 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|gmx:100795311 1 671 + 671 Gaps:3 100.00 674 88.87 0.0 nucleolar GTP-binding protein 1-like
blastp_kegg lcl|pmum:103328908 1 671 + 671 Gaps:8 100.00 675 88.59 0.0 nucleolar GTP-binding protein 1-like
blastp_kegg lcl|pper:PRUPE_ppa002409mg 1 671 + 671 Gaps:8 100.00 675 89.48 0.0 hypothetical protein
blastp_kegg lcl|pmum:103326677 1 671 + 671 Gaps:8 100.00 675 88.89 0.0 nucleolar GTP-binding protein 1-like
blastp_kegg lcl|tcc:TCM_025126 1 671 + 671 Gaps:3 100.00 674 89.91 0.0 Nucleolar GTP-binding protein
blastp_kegg lcl|cic:CICLE_v10004477mg 1 671 + 671 Gaps:5 100.00 676 88.76 0.0 hypothetical protein
blastp_kegg lcl|cit:102614112 1 671 + 671 Gaps:5 100.00 676 88.46 0.0 nucleolar GTP-binding protein 1-like
blastp_kegg lcl|pop:POPTR_0001s26610g 1 671 + 671 Gaps:5 100.00 676 89.64 0.0 POPTRDRAFT_549253 nucleolar GTP-binding protein 1
blastp_kegg lcl|cmo:103487763 1 671 + 671 Gaps:9 100.00 676 86.83 0.0 nucleolar GTP-binding protein 1-like
blastp_kegg lcl|mdm:103403990 1 671 + 671 Gaps:8 100.00 673 88.11 0.0 nucleolar GTP-binding protein 1-like
blastp_pdb 2qu8_A 157 360 + 204 Gaps:12 84.21 228 50.52 2e-53 mol:protein length:228 Putative nucleolar GTP-binding protein 1
blastp_pdb 2e87_A 6 299 + 294 none 82.35 357 30.27 2e-45 mol:protein length:357 Hypothetical protein PH1320
blastp_pdb 1udx_A 171 349 + 179 Gaps:26 38.22 416 32.70 2e-07 mol:protein length:416 the GTP-binding protein Obg
blastp_uniprot_sprot sp|Q9C6I8|NOG1_ARATH 1 671 + 671 Gaps:12 100.00 671 80.48 0.0 Nucleolar GTP-binding protein 1 OS Arabidopsis thaliana GN At1g50920 PE 2 SV 1
blastp_uniprot_sprot sp|Q9BZE4|NOG1_HUMAN 1 671 + 671 Gaps:51 100.00 634 57.26 0.0 Nucleolar GTP-binding protein 1 OS Homo sapiens GN GTPBP4 PE 1 SV 3
blastp_uniprot_sprot sp|Q99ME9|NOG1_MOUSE 1 671 + 671 Gaps:49 100.00 634 57.57 0.0 Nucleolar GTP-binding protein 1 OS Mus musculus GN Gtpbp4 PE 2 SV 3
blastp_uniprot_sprot sp|Q99P77|NOG1_RAT 1 671 + 671 Gaps:60 100.00 637 55.26 0.0 Nucleolar GTP-binding protein 1 OS Rattus norvegicus GN Gtpbp4 PE 2 SV 3
blastp_uniprot_sprot sp|Q54N72|NOG1_DICDI 1 671 + 671 Gaps:43 100.00 674 55.04 0.0 Probable nucleolar GTP-binding protein 1 OS Dictyostelium discoideum GN nog1 PE 1 SV 1
blastp_uniprot_sprot sp|Q9U6A9|NOG1_TRYBB 4 671 + 668 Gaps:35 99.39 655 51.61 0.0 Nucleolar GTP-binding protein 1 OS Trypanosoma brucei brucei GN NOG1 PE 1 SV 1
blastp_uniprot_sprot sp|Q9V411|NOG1_DROME 1 671 + 671 Gaps:29 100.00 652 54.14 0.0 Probable nucleolar GTP-binding protein 1 OS Drosophila melanogaster GN CG8801 PE 2 SV 1
blastp_uniprot_sprot sp|O94659|NOG1_SCHPO 1 671 + 671 Gaps:39 100.00 642 50.78 0.0 Probable nucleolar GTP-binding protein 1 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN nog1 PE 1 SV 2
blastp_uniprot_sprot sp|Q02892|NOG1_YEAST 2 671 + 670 Gaps:45 100.00 647 49.30 0.0 Nucleolar GTP-binding protein 1 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN NOG1 PE 1 SV 1
blastp_uniprot_sprot sp|Q74ZK6|NOG1_ASHGO 2 671 + 670 Gaps:44 100.00 642 49.69 0.0 Nucleolar GTP-binding protein 1 OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) GN NOG1 PE 3 SV 1
rpsblast_cdd gnl|CDD|31281 5 360 + 356 Gaps:16 98.84 346 41.23 1e-100 COG1084 COG1084 Predicted GTPase [General function prediction only].
rpsblast_cdd gnl|CDD|206684 169 355 + 187 Gaps:20 100.00 167 65.27 1e-78 cd01897 NOG Nucleolar GTP-binding protein (NOG). NOG1 is a nucleolar GTP-binding protein present in eukaryotes ranging from trypanosomes to humans. NOG1 is functionally linked to ribosome biogenesis and found in association with the nuclear pore complexes and identified in many preribosomal complexes. Thus defects in NOG1 can lead to defects in 60S biogenesis. The S. cerevisiae NOG1 gene is essential for cell viability and mutations in the predicted G motifs abrogate function. It is a member of the ODN family of GTP-binding proteins that also includes the bacterial Obg and DRG proteins.
rpsblast_cdd gnl|CDD|206668 173 354 + 182 Gaps:26 99.40 167 31.93 2e-27 cd01881 Obg_like Obg-like family of GTPases consist of five subfamilies: Obg DRG YyaF/YchF Ygr210 and NOG1. The Obg-like subfamily consists of five well-delimited ancient subfamilies namely Obg DRG YyaF/YchF Ygr210 and NOG1. Four of these groups (Obg DRG YyaF/YchF and Ygr210) are characterized by a distinct glycine-rich motif immediately following the Walker B motif (G3 box). Obg/CgtA is an essential gene that is involved in the initiation of sporulation and DNA replication in the bacteria Caulobacter and Bacillus but its exact molecular role is unknown. Furthermore several OBG family members possess a C-terminal RNA-binding domain the TGS domain which is also present in threonyl-tRNA synthetase and in bacterial guanosine polyphosphatase SpoT. Nog1 is a nucleolar protein that might function in ribosome assembly. The DRG and Nog1 subfamilies are ubiquitous in archaea and eukaryotes the Ygr210 subfamily is present in archaea and fungi and the Obg and YyaF/YchF subfamilies are ubiquitous in bacteria and eukaryotes. The Obg/Nog1 and DRG subfamilies appear to form one major branch of the Obg family and the Ygr210 and YchF subfamilies form another branch. No GEFs GAPs or GDIs for Obg have been identified.
rpsblast_cdd gnl|CDD|191952 409 463 + 55 none 100.00 55 74.55 4e-24 pfam08155 NOGCT NOGCT (NUC087) domain. This C terminal domain is found in the NOG subfamily of nucleolar GTP-binding proteins.
rpsblast_cdd gnl|CDD|115510 235 292 + 58 none 100.00 58 58.62 1e-22 pfam06858 NOG1 Nucleolar GTP-binding protein 1 (NOG1). This family represents a conserved region of approximately 60 residues in length within nucleolar GTP-binding protein 1 (NOG1). In S. cerevisiae the NOG1 gene has been shown to be essential for cell viability suggesting that NOG1 may play an important role in nucleolar functions. Family members include eukaryotic bacterial and archaeal proteins.
rpsblast_cdd gnl|CDD|202050 170 290 + 121 Gaps:10 100.00 117 29.91 9e-15 pfam01926 MMR_HSR1 50S ribosome-binding GTPase. The full-length GTPase protein is required for the complete activity of the protein of interacting with the 50S ribosome and binding of both adenine and guanine nucleotides with a preference for guanine nucleotide.
rpsblast_cdd gnl|CDD|206685 175 293 + 119 Gaps:33 70.59 170 27.50 6e-11 cd01898 Obg Obg GTPase. The Obg nucleotide binding protein subfamily has been implicated in stress response chromosome partitioning replication initiation mycelium development and sporulation. Obg proteins are among a large group of GTP binding proteins conserved from bacteria to humans. The E. coli homolog ObgE is believed to function in ribosomal biogenesis. Members of the subfamily contain two equally and highly conserved domains a C-terminal GTP binding domain and an N-terminal glycine-rich domain.

16 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PIRSF 1 671 671 PIRSF038919 none none IPR024926
ProSiteProfiles 169 355 187 PS51710 none OBG-type guanine nucleotide-binding (G) domain profile. IPR031167
PANTHER 435 671 237 PTHR11702:SF23 none none none
PANTHER 332 364 33 PTHR11702:SF23 none none none
PANTHER 1 313 313 PTHR11702:SF23 none none none
PRINTS 192 210 19 PR00326 none GTP1/OBG GTP-binding protein family signature IPR006073
PRINTS 219 234 16 PR00326 none GTP1/OBG GTP-binding protein family signature IPR006073
PRINTS 171 191 21 PR00326 none GTP1/OBG GTP-binding protein family signature IPR006073
PANTHER 435 671 237 PTHR11702 none none none
PANTHER 332 364 33 PTHR11702 none none none
PANTHER 1 313 313 PTHR11702 none none none
Pfam 235 292 58 PF06858 none Nucleolar GTP-binding protein 1 (NOG1) IPR010674
Pfam 409 463 55 PF08155 none NOGCT (NUC087) domain IPR012973
Coils 402 423 22 Coil none none none
Gene3D 165 375 211 G3DSA:3.40.50.300 none none IPR027417
SUPERFAMILY 48 312 265 SSF52540 none none IPR027417

0 Localization

0 Qtllist

0 Targeting