GO Term : GO:0004523 RNA-DNA hybrid ribonuclease activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.

0 Cross References

1 Ontology

Name
GO

11 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0004518 nuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids.
GO:0016788 hydrolase activity, acting on ester bonds Catalysis of the hydrolysis of any ester bond.
GO:0004519 endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
GO:0004523 RNA-DNA hybrid ribonuclease activity Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.
GO:0004521 endoribonuclease activity Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
GO:0004540 ribonuclease activity Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters.

9 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0032890.2 Quercus robur 98.1 egn (M=4) 3.1.26.4 - Ribonuclease H.   EC:3.1.26.4 validated
Qrob_P0034940.2 Quercus robur 100.0 egn (M=1) PF03134//PF12874//PF13456 - TB2/DP1, HVA22 family // Zinc-finger of C2H2 type // Reverse transcriptase-like     validated
Qrob_P0035690.2 Quercus robur 21.1 egn (M=1) PF00078//PF13456//PF13966 - Reverse transcriptase (RNA-dependent DNA polymerase) // Reverse transcriptase-like // zinc-binding in reverse transcriptase   EC:2.7.7.49 validated
Qrob_P0135350.2 Quercus robur 96.0 egn (M=1) K10743 - ribonuclease H2 subunit A [EC:3.1.26.4]   EC:3.1.26.4 validated
Qrob_P0138940.2 Quercus robur 0.0 egn (M=1) PF12609//PF13456 - Wound-induced protein // Reverse transcriptase-like     validated
Qrob_P0138960.2 Quercus robur 0.0 egn (M=17) PF13456 - Reverse transcriptase-like     validated
Qrob_P0138970.2 Quercus robur 0.0 egn (M=17) PF13456 - Reverse transcriptase-like     validated
Qrob_P0252820.2 Quercus robur 0.0 egn (M=17) PF13456 - Reverse transcriptase-like     validated
Qrob_P0701920.2 Quercus robur 100.0 egn (M=4) 3.1.26.4 - Ribonuclease H.   EC:3.1.26.4 validated

10 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016891 GO:0004523
is_a GO:0003824 GO:0004523
is_a GO:0016787 GO:0004523
is_a GO:0004521 GO:0004523
is_a GO:0004540 GO:0004523
is_a GO:0004519 GO:0004523
is_a GO:0004518 GO:0004523
is_a GO:0003674 GO:0004523
is_a GO:0016788 GO:0004523
is_a GO:0016893 GO:0004523

18 Synonyms

Name Type
ribonuclease H2 activity synonym
ribonuclease H3 activity synonym
ribonuclease H activity synonym
ribonuclease H1 activity synonym
RNase H1 activity synonym
RNase H2 activity synonym
RNA*DNA hybrid ribonucleotidohydrolase activity synonym
RNase H activity synonym
endoribonuclease H (calf thymus) synonym
endoribonuclease0 H activity synonym
calf thymus ribonuclease H activity synonym
endoribonuclease H synonym
hybridase (ribonuclease H) synonym
hybridase activity synonym
hybrid nuclease activity synonym
hybrid ribonuclease activity synonym
GO:0004524 alt_id
RNase H3 activity synonym