Protein : Qrob_P0252820.2 Q. robur
Protein Identifier  ? Qrob_P0252820.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=17) PF13456 - Reverse transcriptase-like Gene Prediction Quality  validated
Protein length 

Sequence

Length: 191  
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0 Synonyms

2 GO Terms

Identifier Name Description
GO:0003676 nucleic acid binding Interacting selectively and non-covalently with any nucleic acid.
GO:0004523 RNA-DNA hybrid ribonuclease activity Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.

13 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|brp:103833563 6 186 + 181 Gaps:9 44.23 416 34.24 2e-23 putative ribonuclease H protein At1g65750
blastp_kegg lcl|brp:103840360 6 178 + 173 Gaps:7 56.49 308 35.06 7e-23 putative ribonuclease H protein At1g65750
blastp_kegg lcl|tcc:TCM_035532 6 187 + 182 Gaps:2 46.27 389 32.78 8e-23 Polynucleotidyl transferase putative
blastp_kegg lcl|tcc:TCM_019529 6 187 + 182 Gaps:6 41.10 438 32.22 2e-21 Non-LTR retroelement reverse transcriptase-like
blastp_kegg lcl|brp:103868641 2 183 + 182 Gaps:8 41.07 448 34.24 4e-21 putative ribonuclease H protein At1g65750
blastp_kegg lcl|tcc:TCM_043935 1 187 + 187 Gaps:4 44.63 419 30.48 4e-21 Polynucleotidyl transferase putative
blastp_kegg lcl|brp:103845224 2 186 + 185 Gaps:9 61.04 308 33.51 5e-21 putative ribonuclease H protein At1g65750
blastp_kegg lcl|brp:103849799 1 178 + 178 Gaps:11 53.92 332 35.75 7e-21 putative ribonuclease H protein At1g65750
blastp_kegg lcl|brp:103849222 1 178 + 178 Gaps:11 17.71 1011 36.87 7e-21 putative ribonuclease H protein At1g65750
blastp_kegg lcl|tcc:TCM_016968 79 180 + 102 none 29.65 344 45.10 2e-20 RNA-binding (RRM/RBD/RNP motifs) family protein isoform 1
blastp_uniprot_sprot sp|P0C2F6|RNHX1_ARATH 6 177 + 172 Gaps:7 27.90 620 32.95 6e-20 Putative ribonuclease H protein At1g65750 OS Arabidopsis thaliana GN At1g65750 PE 3 SV 1
rpsblast_cdd gnl|CDD|187690 103 190 + 88 none 71.54 123 35.23 4e-14 cd06222 RNase_H RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner. Ribonuclease H (RNase H) enzymes are divided into two major families Type 1 and Type 2 based on amino acid sequence similarities and biochemical properties. RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner in the presence of divalent cations. RNase H is widely present in various organisms including bacteria archaea and eukaryotes. Most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology Type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site residues and have the same catalytic mechanism and functions in cells. RNase H is involved in DNA replication repair and transcription. One of the important functions of RNase H is to remove Okazaki fragments during DNA replication. RNase H inhibitors have been explored as an anti-HIV drug target because RNase H inactivation inhibits reverse transcription.
rpsblast_cdd gnl|CDD|187703 101 180 + 80 Gaps:2 62.50 128 33.75 9e-07 cd09279 RNase_HI_archaeal_like RNAse HI family that includes Archaeal RNase HI. Ribonuclease H (RNase H) is classified into two evolutionarily unrelated families type 1 (prokaryotic RNase HI eukaryotic RNase H1 and viral RNase H) and type 2 (prokaryotic RNase HII and HIII and eukaryotic RNase H2). RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner. RNase H is involved in DNA replication repair and transcription. RNase H is widely present in various organisms including bacteria archaea and eukaryotes and most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology Type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site (DEDD) residues and have the same catalytic mechanism and functions in cells. One of the important functions of RNase H is to remove Okazaki fragments during DNA replication. Most archaeal genomes contain only type 2 RNase H (RNase HII) however a few contain RNase HI as well. Although archaeal RNase HI sequences conserve the DEDD active-site motif they lack other common features important for catalytic function such as the basic protrusion region. Archaeal RNase HI homologs are more closely related to retroviral RNase HI than bacterial and eukaryotic type I RNase H in enzymatic properties.

4 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
SUPERFAMILY 98 183 86 SSF53098 none none IPR012337
Gene3D 103 187 85 G3DSA:3.30.420.10 none none IPR012337
Pfam 142 182 41 PF13456 none Reverse transcriptase-like none
ProSiteProfiles 96 190 95 PS50879 none RNase H domain profile. IPR002156

0 Localization

2 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2015_nP_3P Qrob_Chr12 12 v_10140_295 v_838_303 16 14,69 18,01 lod 5.1 13.7
Bourran2_2015_nSecLBD_3P Qrob_Chr12 12 s_A4YYC_633 s_2F1IZB_703 18,64 18,01 21,53 lod 6.5 17.2

0 Targeting