GO Term : GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2.

0 Cross References

1 Ontology

Name
GO

7 Parents

Identifier Name Description
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide.
GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity Catalysis of the reaction: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0004738 pyruvate dehydrogenase activity Catalysis of the oxidative decarboxylation of pyruvate.

6 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0237890.2 Quercus robur 96.0 egn (M=6) K00162 - pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]   EC:1.2.4.1 validated
Qrob_P0243840.2 Quercus robur 100.0 egn (M=6) K00162 - pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]   EC:1.2.4.1 validated
Qrob_P0537490.2 Quercus robur 97.0 egn (M=6) K00162 - pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]   EC:1.2.4.1 validated
Qrob_P0537510.2 Quercus robur 0.0 egn (M=6) K00162 - pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]   EC:1.2.4.1 validated
Qrob_P0537520.2 Quercus robur 0.0 egn (M=6) K00162 - pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]   EC:1.2.4.1 validated
Qrob_P0631140.2 Quercus robur 100.0 egn (M=1) PTHR11516//PTHR11516:SF30 - PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT (BACTERIAL AND ORGANELLAR) // SUBFAMILY NOT NAMED   EC:1.2.4.1 validated

6 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0004738 GO:0004739
is_a GO:0016624 GO:0004739
is_a GO:0003824 GO:0004739
is_a GO:0016491 GO:0004739
is_a GO:0016903 GO:0004739
is_a GO:0003674 GO:0004739

6 Synonyms

Name Type
MtPDC (mitochondrial pyruvate dehydogenase complex) activity synonym
PDH synonym
pyruvate dehydrogenase (lipoamide) activity synonym
pyruvate dehydrogenase complex activity synonym
pyruvate:dihydrolipoyllysine-residue acetyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating) synonym
pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating) activity synonym