GO Term : GO:0016593 Cdc73/Paf1 complex GO

Namespace  cellular_component Obsolete  false
description  A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.

0 Cross References

1 Ontology

Name
GO

30 Parents

Identifier Name Description
GO:0005634 nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0016593 Cdc73/Paf1 complex A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:0043231 intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:1902494 catalytic complex A protein complex which is capable of catalytic activity.
GO:0044424 intracellular part Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0044428 nuclear part Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.
GO:0044422 organelle part Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
GO:0044446 intracellular organelle part A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
GO:0043226 organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GO:0043227 membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0043229 intracellular organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0044451 nucleoplasm part Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus.
GO:0043233 organelle lumen The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.
GO:0031981 nuclear lumen The volume enclosed by the nuclear inner membrane.
GO:0070013 intracellular organelle lumen An organelle lumen that is part of an intracellular organelle.
GO:0005654 nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.
GO:0031974 membrane-enclosed lumen The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.
GO:1990234 transferase complex A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor).
GO:0061695 transferase complex, transferring phosphorus-containing groups A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GO:0000428 DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.
GO:0030880 RNA polymerase complex Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits.
GO:0055029 nuclear DNA-directed RNA polymerase complex A protein complex, located in the nucleus, that possesses DNA-directed RNA polymerase activity.
GO:0016591 DNA-directed RNA polymerase II, holoenzyme Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA.
GO:0008023 transcription elongation factor complex Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation.

8 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0068110.2 Quercus robur 100.0 egn (M=1) K15175 - parafibromin     validated
Qrob_P0166680.2 Quercus robur 100.0 egn (M=2) K15177 - RNA polymerase-associated protein LEO1     validated
Qrob_P0166710.2 Quercus robur 0.0 egn (M=2) K15177 - RNA polymerase-associated protein LEO1     validated
Qrob_P0178680.2 Quercus robur 100.0 egn (M=1) K15174 - RNA polymerase II-associated factor 1     validated
Qrob_P0189860.2 Quercus robur 100.0 egn (M=2) K15176 - RNA polymerase-associated protein CTR9     validated
Qrob_P0189870.2 Quercus robur 100.0 egn (M=2) K15176 - RNA polymerase-associated protein CTR9     validated
Qrob_P0287430.2 Quercus robur 100.0 egn (M=2) K15178 - RNA polymerase-associated protein RTF1     validated
Qrob_P0340830.2 Quercus robur 100.0 egn (M=2) K15178 - RNA polymerase-associated protein RTF1     validated

38 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0016591 GO:0016593
is_a GO:0008023 GO:0016593
part of GO:0061695 GO:0016593
part of GO:0031981 GO:0016593
part of GO:1902494 GO:0016593
is_a GO:0044422 GO:0016593
is_a GO:0044446 GO:0016593
part of GO:0005622 GO:0016593
part of GO:0005623 GO:0016593
is_a GO:0043234 GO:0016593
is_a GO:0044424 GO:0016593
is_a GO:0044464 GO:0016593
part of GO:0044464 GO:0016593
is_a GO:0044428 GO:0016593
part of GO:0055029 GO:0016593
part of GO:1990234 GO:0016593
part of GO:0044446 GO:0016593
part of GO:0031974 GO:0016593
part of GO:0032991 GO:0016593
part of GO:0044424 GO:0016593
part of GO:0044422 GO:0016593
is_a GO:0005575 GO:0016593
is_a GO:0044451 GO:0016593
part of GO:0044428 GO:0016593
part of GO:0070013 GO:0016593
part of GO:0005654 GO:0016593
part of GO:0043231 GO:0016593
part of GO:0043233 GO:0016593
part of GO:0043234 GO:0016593
part of GO:0005634 GO:0016593

2 Synonyms

Name Type
Paf1 complex synonym
Paf1p complex synonym