GO Term : GO:0004326 tetrahydrofolylpolyglutamate synthase activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: ATP + tetrahydrofolyl-(Glu)(n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-(Glu)(n+1).

0 Cross References

1 Ontology

Name
GO

6 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016874 ligase activity Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016879 ligase activity, forming carbon-nitrogen bonds Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016881 acid-amino acid ligase activity Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0004326 tetrahydrofolylpolyglutamate synthase activity Catalysis of the reaction: ATP + tetrahydrofolyl-(Glu)(n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-(Glu)(n+1).
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

6 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0590420.2 Quercus robur 100.0 egn (M=2) 6.3.2.17 - Tetrahydrofolate synthase.   EC:6.3.2.17 validated
Qrob_P0590440.2 Quercus robur 68.0 egn (M=2) 6.3.2.17 - Tetrahydrofolate synthase.   EC:6.3.2.17 validated
Qrob_P0611060.2 Quercus robur 96.2 egn (M=4) 6.3.2.12 - Dihydrofolate synthase.   EC:6.3.2.12 validated
Qrob_P0611080.2 Quercus robur 0.0 egn (M=4) 6.3.2.12 - Dihydrofolate synthase.   EC:6.3.2.12 validated
Qrob_P0611090.2 Quercus robur 0.0 egn (M=4) 6.3.2.12 - Dihydrofolate synthase.   EC:6.3.2.12 validated
Qrob_P0611120.2 Quercus robur 0.0 egn (M=4) 6.3.2.12 - Dihydrofolate synthase.   EC:6.3.2.12 validated

5 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016881 GO:0004326
is_a GO:0003674 GO:0004326
is_a GO:0016879 GO:0004326
is_a GO:0003824 GO:0004326
is_a GO:0016874 GO:0004326

15 Synonyms

Name Type
tetrahydropteroyl-[gamma-polyglutamate]:L-glutamate gamma-ligase (ADP-forming) synonym
tetrahydrofolyl-[gamma-Glu]n:L-glutamate gamma-ligase (ADP-forming) synonym
tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) activity synonym
tetrahydrofolate synthase activity synonym
N10-formyltetrahydropteroyldiglutamate synthetase activity synonym
N(10)-formyltetrahydropteroyldiglutamate synthetase activity synonym
FPGS activity synonym
formyltetrahydropteroyldiglutamate synthetase activity synonym
folylpolyglutamyl synthetase activity synonym
folylpolyglutamate synthetase activity synonym
folylpolyglutamate synthase activity synonym
folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase activity synonym
folylpoly-gamma-glutamate synthase activity synonym
folylpoly(gamma-glutamate) synthase activity synonym
folate polyglutamate synthetase activity synonym