GO Term : GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity GO
Namespace  molecular_function Obsolete  false
description  Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
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0 Cross References

1 Ontology

Name
GO

11 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0004518 nuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids.
GO:0016788 hydrolase activity, acting on ester bonds Catalysis of the hydrolysis of any ester bond.
GO:0004519 endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
GO:0016829 lyase activity Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0004520 endodeoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
GO:0004536 deoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
GO:0016835 carbon-oxygen lyase activity Catalysis of the breakage of a carbon-oxygen bond.

1 Protein

Protein Identifier
Organism . Name 		Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0221470.2 Quercus robur 100.0 egn (M=1) 3.2.2.23 - DNA-formamidopyrimidine glycosylase.   EC:4.2.99.18, EC:3.2.2.23 validated

16 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0003906 GO:0000703
is_a GO:0003906 GO:0000704
is_a GO:0004520 GO:0003906
is_a GO:0016835 GO:0003906
is_a GO:0016788 GO:0003906
is_a GO:0016787 GO:0003906
is_a GO:0004536 GO:0003906
is_a GO:0003674 GO:0003906
is_a GO:0004519 GO:0003906
is_a GO:0004518 GO:0003906
is_a GO:0016829 GO:0003906
is_a GO:0003824 GO:0003906
is_a GO:0003906 GO:0008534
is_a GO:0003906 GO:0034039
is_a GO:0003906 GO:0034042
is_a GO:0003906 GO:0034043

15 Synonyms

Name Type
endonuclease VIII activity synonym
AP endonuclease class I activity synonym
X-ray endonuclease III synonym
Phage-T4 UV endonuclease activity synonym
phage-T4 UV endonuclease synonym
Phage-T(4) UV endonuclease activity synonym
Micrococcus luteus UV endonuclease activity synonym
micrococcus luteus UV endonuclease synonym
endodeoxyribonuclease (apurinic or apyrimidinic) activity synonym
E. coli endonuclease III activity synonym
E. coli endonuclease III synonym
DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity synonym
deoxyribonuclease (apurinic or apyrimidinic) activity synonym
AP site-DNA 5'-phosphomonoester-lyase activity synonym
AP lyase activity synonym