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GO:0003824
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catalytic activity
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Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
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GO:0016798
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hydrolase activity, acting on glycosyl bonds
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Catalysis of the hydrolysis of any glycosyl bond. |
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GO:0016787
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hydrolase activity
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Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. |
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GO:0004518
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nuclease activity
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Catalysis of the hydrolysis of ester linkages within nucleic acids. |
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GO:0016788
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hydrolase activity, acting on ester bonds
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Catalysis of the hydrolysis of any ester bond. |
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GO:0004519
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endonuclease activity
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Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. |
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GO:0016829
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lyase activity
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Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring. |
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GO:0016799
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hydrolase activity, hydrolyzing N-glycosyl compounds
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Catalysis of the hydrolysis of any N-glycosyl bond. |
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GO:0003906
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DNA-(apurinic or apyrimidinic site) lyase activity
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Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. |
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GO:0003674
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molecular_function
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Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. |
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GO:0004520
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endodeoxyribonuclease activity
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Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. |
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GO:0004536
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deoxyribonuclease activity
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Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid. |
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GO:0019104
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DNA N-glycosylase activity
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Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site. |
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GO:0000702
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oxidized base lesion DNA N-glycosylase activity
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Catalysis of the removal of oxidized bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site. |
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GO:0000703
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oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
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Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site. |
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GO:0016835
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carbon-oxygen lyase activity
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Catalysis of the breakage of a carbon-oxygen bond. |
