GO Term : GO:0016992 lipoate synthase activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: protein N6-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl.

0 Cross References

1 Ontology

Name
GO

10 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0016874 ligase activity Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016992 lipoate synthase activity Catalysis of the reaction: protein N6-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl.
GO:0016879 ligase activity, forming carbon-nitrogen bonds Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016783 sulfurtransferase activity Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0016782 transferase activity, transferring sulfur-containing groups Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (acceptor).
GO:0070283 radical SAM enzyme activity Catalysis of a reaction in which S-adenosyl-L-methionine (SAM) undergoes reductive cleavage to serve as a source of the 5'-deoxyadenosyl radical.
GO:0016979 lipoate-protein ligase activity Catalysis of the formation of carbon-nitrogen bonds between lipoate (5-(1,2-dithiolan-3-yl)pentanoate) and a protein.

3 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0120040.2 Quercus robur 97.1 egn (M=1) 1.8.7.2 - Ferredoxin:thioredoxin reductase.   EC:1.8.7.2 validated
Qrob_P0143270.2 Quercus robur 100.0 egn (M=2) 2.8.1.8 - Lipoyl synthase.   EC:2.8.1.8 validated
Qrob_P0637150.2 Quercus robur 98.0 egn (M=2) 2.8.1.8 - Lipoyl synthase.   EC:2.8.1.8 validated

9 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0070283 GO:0016992
is_a GO:0016783 GO:0016992
is_a GO:0016979 GO:0016992
is_a GO:0003824 GO:0016992
is_a GO:0016740 GO:0016992
is_a GO:0016879 GO:0016992
is_a GO:0003674 GO:0016992
is_a GO:0016874 GO:0016992
is_a GO:0016782 GO:0016992

7 Synonyms

Name Type
LipA synonym
LS synonym
protein 6-N-(octanoyl)lysine:sulfur sulfurtransferase activity synonym
lipoic acid synthase synonym
lipoyl synthase activity synonym
protein N6-(octanoyl)lysine:sulfur sulfurtransferase activity synonym
GO:0017140 alt_id