GO Term : GO:0016272 prefoldin complex GO

Namespace  cellular_component Obsolete  false
description  A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.

0 Cross References

1 Ontology

Name
GO

4 Parents

Identifier Name Description
GO:0016272 prefoldin complex A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

4 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0052360.2 Quercus robur 100.0 egn (M=1) K17560 - unconventional prefoldin RPB5 interactor 1     validated
Qrob_P0248820.2 Quercus robur 100.0 egn (M=1) K09550 - prefoldin subunit 4     validated
Qrob_P0517950.2 Quercus robur 85.1 egn (M=1) K04798 - prefoldin beta subunit     validated
Qrob_P0747980.2 Quercus robur 98.0 egn (M=1) K09548 - prefoldin subunit 1     validated

3 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0043234 GO:0016272
is_a GO:0005575 GO:0016272
is_a GO:0032991 GO:0016272

1 Synonyms

Name Type
GIM complex synonym