Protein : Qrob_P0052360.2 Q. robur
Protein Identifier  ? Qrob_P0052360.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) K17560 - unconventional prefoldin RPB5 interactor 1 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 378  
Kegg Orthology  K17560
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0006457 protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
GO:0051082 unfolded protein binding Interacting selectively and non-covalently with an unfolded protein.
GO:0016272 prefoldin complex A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.

19 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|cit:102629247 1 373 + 373 Gaps:72 78.77 438 60.00 6e-110 RNA polymerase II subunit 5-mediating protein homolog
blastp_kegg lcl|cic:CICLE_v10015278mg 1 283 + 283 Gaps:34 97.00 300 61.86 1e-101 hypothetical protein
blastp_kegg lcl|vvi:100254110 1 374 + 374 Gaps:73 88.53 340 60.13 2e-100 uncharacterized LOC100254110
blastp_kegg lcl|mdm:103444448 1 374 + 374 Gaps:44 85.71 385 61.21 8e-98 RNA polymerase II subunit 5-mediating protein homolog
blastp_kegg lcl|pmum:103327088 1 371 + 371 Gaps:38 78.55 429 57.86 9e-98 RNA polymerase II subunit 5-mediating protein homolog
blastp_kegg lcl|cic:CICLE_v10015471mg 1 228 + 228 Gaps:11 67.81 320 71.43 4e-96 hypothetical protein
blastp_kegg lcl|tcc:TCM_026905 11 353 + 343 Gaps:44 71.99 482 51.87 6e-95 Prefoldin chaperone subunit family protein putative isoform 1
blastp_kegg lcl|cit:102625230 1 228 + 228 Gaps:11 53.85 403 71.43 1e-94 RNA polymerase II subunit 5-mediating protein homolog
blastp_kegg lcl|csv:101205427 1 372 + 372 Gaps:48 88.53 375 56.02 5e-94 uncharacterized LOC101205427
blastp_kegg lcl|fve:101303426 7 374 + 368 Gaps:55 84.82 369 58.15 1e-87 uncharacterized protein LOC101303426
blastp_uniprot_sprot sp|Q54HG4|RMP_DICDI 24 157 + 134 Gaps:4 28.22 489 35.51 7e-22 RNA polymerase II subunit 5-mediating protein homolog OS Dictyostelium discoideum GN rmp PE 3 SV 2
blastp_uniprot_sprot sp|O94763|RMP_HUMAN 22 156 + 135 Gaps:15 24.30 535 34.62 2e-17 Unconventional prefoldin RPB5 interactor 1 OS Homo sapiens GN URI1 PE 1 SV 3
blastp_uniprot_sprot sp|Q3B7M7|RMP_BOVIN 22 156 + 135 Gaps:9 24.81 524 34.62 3e-17 Unconventional prefoldin RPB5 interactor OS Bos taurus GN URI1 PE 2 SV 1
blastp_uniprot_sprot sp|Q3TLD5|RMP_MOUSE 22 156 + 135 Gaps:9 24.48 531 32.31 1e-15 Unconventional prefoldin RPB5 interactor OS Mus musculus GN Uri1 PE 1 SV 2
blastp_uniprot_sprot sp|Q3IUJ7|PFDA_NATPD 38 125 + 88 Gaps:2 56.95 151 33.72 8e-06 Prefoldin subunit alpha OS Natronomonas pharaonis (strain ATCC 35678 / DSM 2160) GN pfdA PE 3 SV 1
rpsblast_cdd gnl|CDD|202504 31 147 + 117 Gaps:1 98.33 120 27.97 6e-14 pfam02996 Prefoldin Prefoldin subunit. This family comprises of several prefoldin subunits. The biogenesis of the cytoskeletal proteins actin and tubulin involves interaction of nascent chains of each of the two proteins with the oligomeric protein prefoldin (PFD) and their subsequent transfer to the cytosolic chaperonin CCT (chaperonin containing TCP-1). Electron microscopy shows that eukaryotic PFD which has a similar structure to its archaeal counterpart interacts with unfolded actin along the tips of its projecting arms. In its PFD-bound state actin seems to acquire a conformation similar to that adopted when it is bound to CCT.
rpsblast_cdd gnl|CDD|29840 32 148 + 117 Gaps:1 91.47 129 24.58 3e-12 cd00584 Prefoldin_alpha Prefoldin alpha subunit Prefoldin is a hexameric molecular chaperone complex found in both eukaryotes and archaea that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits the two subunits being evolutionarily related. In archaea there is usually only one gene for each subunit while in eukaryotes there two or more paralogous genes encoding each subunit adding heterogeneity to the structure of the hexamer. The structure of the complex consists of a double beta barrel assembly with six protruding coiled-coils..
rpsblast_cdd gnl|CDD|29842 32 147 + 116 Gaps:1 90.70 129 21.37 3e-09 cd00890 Prefoldin Prefoldin is a hexameric molecular chaperone complex found in both eukaryotes and archaea that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits the two subunits being evolutionarily related. In archaea there is usually only one gene for each subunit while in eukaryotes there two or more paralogous genes encoding each subunit adding heterogeneity to the structure of the hexamer. The structure of the complex consists of a double beta barrel assembly with six protruding coiled-coils..
rpsblast_kog gnl|CDD|38340 35 268 + 234 Gaps:11 44.94 514 26.41 2e-15 KOG3130 KOG3130 KOG3130 Uncharacterized conserved protein [Function unknown].

12 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 32 146 115 PF02996 none Prefoldin subunit IPR004127
PANTHER 5 189 185 PTHR15111:SF0 none none none
PANTHER 5 189 185 PTHR15111 none none none
Coils 196 231 36 Coil none none none
SUPERFAMILY 22 139 118 SSF46579 none none IPR009053
Coils 233 273 41 Coil none none none
Coils 21 49 29 Coil none none none
PANTHER 213 306 94 PTHR15111 none none none
Coils 115 136 22 Coil none none none
PANTHER 213 306 94 PTHR15111:SF0 none none none
Gene3D 23 143 121 G3DSA:1.10.287.370 none none IPR009053
TIGRFAM 25 138 114 TIGR00293 none TIGR00293: prefoldin, alpha subunit IPR011599

0 Localization

10 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran2_2014_aSeqBC_A4 Qrob_Chr08 8 v_15999_278 v_AP13YL15_395 32,52 4,22 57,22 lod 2,7561 6,7
Bourran2_2014_nFork*_A4 Qrob_Chr08 8 PIE175 s_1CD7GJ_1398 31,22 5,24 57,24 lod 2,6724 6,8
Bourran2_2014_nLBD*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,25 0 35,55 lod 2,5951 6
Bourran2_2014_nP*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,19 0 31,97 lod 2,8472 6
Bourran2_2014_nPriLBD_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,36 0 30,43 lod 2,5806 5,1
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nPriBD_3P Qrob_Chr11 11 v_11486_194 s_1AT3E_2335 5,54 0,4 20,6 lod 2,6345 5,9

0 Targeting