Protein : Qrob_P0517950.2 Q. robur

Protein Identifier  ? Qrob_P0517950.2 Organism . Name  Quercus robur
Score  85.1 Score Type  egn
Protein Description  (M=1) K04798 - prefoldin beta subunit Gene Prediction Quality  validated
Protein length 

Sequence

Length: 134  
Kegg Orthology  K04798

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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0006457 protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
GO:0051082 unfolded protein binding Interacting selectively and non-covalently with an unfolded protein.
GO:0016272 prefoldin complex A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.

24 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|tcc:TCM_029496 2 119 + 118 Gaps:7 95.42 131 76.00 2e-55 Prefoldin 6 isoform 1
blastp_kegg lcl|sly:101265944 1 119 + 119 Gaps:7 96.92 130 73.81 3e-54 prefoldin subunit 6-like
blastp_kegg lcl|mdm:103443999 1 116 + 116 Gaps:9 93.08 130 76.86 5e-54 prefoldin subunit 6-like
blastp_kegg lcl|pop:POPTR_0004s13700g 1 119 + 119 Gaps:7 96.92 130 74.60 6e-54 POPTRDRAFT_714512 prefoldin family protein
blastp_kegg lcl|sot:102599302 1 119 + 119 Gaps:7 96.92 130 73.81 7e-54 prefoldin subunit 6-like
blastp_kegg lcl|pmum:103328236 1 119 + 119 Gaps:7 96.92 130 73.02 1e-53 prefoldin subunit 6-like
blastp_kegg lcl|pxb:103951271 1 116 + 116 Gaps:9 93.08 130 76.86 1e-53 prefoldin subunit 6
blastp_kegg lcl|mdm:103446192 1 109 + 109 Gaps:7 89.23 130 77.59 2e-53 prefoldin subunit 6-like
blastp_kegg lcl|mdm:103422341 1 109 + 109 Gaps:7 89.23 130 77.59 2e-53 prefoldin subunit 6-like
blastp_kegg lcl|cic:CICLE_v10017164mg 1 106 + 106 Gaps:7 86.92 130 80.53 5e-53 hypothetical protein
blastp_uniprot_sprot sp|Q17Q89|PFD6_BOVIN 20 109 + 90 none 69.77 129 47.78 1e-18 Prefoldin subunit 6 OS Bos taurus GN PFDN6 PE 2 SV 1
blastp_uniprot_sprot sp|Q03958|PFD6_MOUSE 20 109 + 90 none 70.87 127 47.78 2e-18 Prefoldin subunit 6 OS Mus musculus GN Pfdn6 PE 2 SV 1
blastp_uniprot_sprot sp|O15212|PFD6_HUMAN 20 109 + 90 none 69.77 129 47.78 2e-18 Prefoldin subunit 6 OS Homo sapiens GN PFDN6 PE 1 SV 1
blastp_uniprot_sprot sp|Q5TJE6|PFD6_CANFA 20 109 + 90 none 69.77 129 47.78 2e-18 Prefoldin subunit 6 OS Canis familiaris GN PFDN6 PE 3 SV 1
blastp_uniprot_sprot sp|Q9VW56|PFD6_DROME 3 106 + 104 Gaps:3 85.60 125 42.06 5e-16 Probable prefoldin subunit 6 OS Drosophila melanogaster GN CG7770 PE 2 SV 1
blastp_uniprot_sprot sp|A8Y197|PFD6_CAEBR 14 107 + 94 Gaps:7 78.91 128 38.61 6e-16 Probable prefoldin subunit 6 OS Caenorhabditis briggsae GN pfd-6 PE 3 SV 1
blastp_uniprot_sprot sp|P52554|PFD6_CAEEL 14 106 + 93 Gaps:7 79.37 126 40.00 9e-16 Probable prefoldin subunit 6 OS Caenorhabditis elegans GN pfd-6 PE 2 SV 1
blastp_uniprot_sprot sp|O14450|PFD6_SCHPO 7 90 + 84 none 73.68 114 40.48 1e-13 Probable prefoldin subunit 6 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN SPAC3A11.13 PE 3 SV 1
blastp_uniprot_sprot sp|Q54M71|PFD6_DICDI 12 98 + 87 Gaps:1 62.86 140 42.05 2e-13 Probable prefoldin subunit 6 OS Dictyostelium discoideum GN pfdn6 PE 3 SV 1
blastp_uniprot_sprot sp|P52553|PFD6_YEAST 7 98 + 92 none 80.70 114 38.04 3e-11 Prefoldin subunit 6 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN YKE2 PE 1 SV 1
rpsblast_cdd gnl|CDD|202045 8 104 + 97 none 91.51 106 43.30 6e-15 pfam01920 Prefoldin_2 Prefoldin subunit. This family includes prefoldin subunits that are not detected by pfam02996.
rpsblast_cdd gnl|CDD|29841 19 106 + 88 none 83.81 105 39.77 5e-12 cd00632 Prefoldin_beta Prefoldin beta Prefoldin is a hexameric molecular chaperone complex composed of two evolutionarily related subunits (alpha and beta) which are found in both eukaryotes and archaea. Prefoldin binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The hexameric structure consists of a double beta barrel assembly with six protruding coiled-coils. The alpha prefoldin subunits have two beta hairpin structures while the beta prefoldin subunits (this CD) have only one hairpin that is most similar to the second hairpin of the alpha subunit. The prefoldin hexamer consists of two alpha and four beta subunits and is assembled from the beta hairpins of all six subunits. The alpha subunits initially dimerize providing a structural nucleus for the assembly of the beta subunits. In archaea there is usually only one gene for each subunit while in eukaryotes there two or more paralogous genes encoding each subunit adding heterogeneity to the structure of the hexamer..
rpsblast_cdd gnl|CDD|31572 7 106 + 100 none 84.03 119 28.00 4e-09 COG1382 GimC Prefoldin chaperonin cofactor [Posttranslational modification protein turnover chaperones].
rpsblast_kog gnl|CDD|38688 8 106 + 99 Gaps:7 88.33 120 49.06 1e-22 KOG3478 KOG3478 KOG3478 Prefoldin subunit 6 KE2 family [Posttranslational modification protein turnover chaperones].

7 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Coils 78 106 29 Coil none none none
Coils 7 28 22 Coil none none none
PANTHER 7 106 100 PTHR21431:SF0 none none none
Gene3D 7 105 99 G3DSA:1.10.287.370 none none IPR009053
PANTHER 7 106 100 PTHR21431 none none none
SUPERFAMILY 7 106 100 SSF46579 none none IPR009053
Pfam 9 105 97 PF01920 none Prefoldin subunit IPR002777

0 Localization

0 Qtllist

0 Targeting