GO Term : GO:0004197 cysteine-type endopeptidase activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.

0 Cross References

1 Ontology

Name
GO

8 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0008234 cysteine-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0004197 cysteine-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0008233 peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GO:0004175 endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0070011 peptidase activity, acting on L-amino acid peptides Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.

7 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0049280.2 Quercus robur 85.0 egn (M=5) KOG1546 - Metacaspase involved in regulation of apoptosis [Cell cycle control cell division chromosome partitioning Posttranslational modification protein turnover chaperones].     validated
Qrob_P0286130.2 Quercus robur 46.1 egn (M=2) PF00656//PF06943 - Caspase domain // LSD1 zinc finger     validated
Qrob_P0322910.2 Quercus robur 97.0 egn (M=2) 3.4.22.1 - Cathepsin B.   EC:3.4.22.1 validated
Qrob_P0407070.2 Quercus robur 98.1 egn (M=2) PF00656//PF06943 - Caspase domain // LSD1 zinc finger     validated
Qrob_P0598170.2 Quercus robur 66.7 egn (M=5) KOG1546 - Metacaspase involved in regulation of apoptosis [Cell cycle control cell division chromosome partitioning Posttranslational modification protein turnover chaperones].     validated
Qrob_P0598180.2 Quercus robur 65.3 egn (M=5) KOG1546 - Metacaspase involved in regulation of apoptosis [Cell cycle control cell division chromosome partitioning Posttranslational modification protein turnover chaperones].     validated
Qrob_P0662960.2 Quercus robur 0.0 egn (M=3) PTHR31683:SF8 - MAJOR POLLEN ALLERGEN-LIKE PROTEIN (PTHR31683:SF8)   EC:4.2.2.2 validated

14 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0004175 GO:0004197
is_a GO:0008234 GO:0004197
is_a GO:0016787 GO:0004197
is_a GO:0003674 GO:0004197
is_a GO:0003824 GO:0004197
is_a GO:0008233 GO:0004197
is_a GO:0070011 GO:0004197
is_a GO:0004197 GO:0004198
is_a GO:0004197 GO:0070137
is_a GO:0004197 GO:0070139
is_a GO:0004197 GO:0097153
is_a GO:0004197 GO:0097199
is_a GO:0004197 GO:0097200
is_a GO:0004197 GO:0097299

4 Synonyms

Name Type
metacaspase activity synonym
thiol endopeptidase activity synonym
lysosomal cysteine-type endopeptidase synonym
caspase activity synonym