Protein : Qrob_P0322910.2 Q. robur
Protein Identifier  ? Qrob_P0322910.2 Organism . Name  Quercus robur
Score  97.0 Score Type  egn
Protein Description  (M=2) 3.4.22.1 - Cathepsin B. Code Enzyme  EC:3.4.22.1
Gene Prediction Quality  validated Protein length 

Sequence

Length: 372  
Kegg Orthology  K01363
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0006508 proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
GO:0008234 cysteine-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0004197 cysteine-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.

43 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pper:PRUPE_ppa007538mg 6 371 + 366 Gaps:15 96.98 364 79.60 0.0 hypothetical protein
blastp_kegg lcl|pmum:103327235 6 371 + 366 Gaps:15 96.98 364 79.32 0.0 cathepsin B
blastp_kegg lcl|mdm:103405978 6 367 + 362 Gaps:14 95.87 363 77.59 0.0 cathepsin B-like
blastp_kegg lcl|pxb:103933562 6 367 + 362 Gaps:14 95.87 363 77.59 0.0 cathepsin B-like
blastp_kegg lcl|pop:POPTR_0002s18510g 15 370 + 356 Gaps:14 95.80 357 80.41 0.0 POPTRDRAFT_552399 putative cathepsin B-like protease family protein
blastp_kegg lcl|cic:CICLE_v10020859mg 1 370 + 370 Gaps:17 99.72 354 77.62 0.0 hypothetical protein
blastp_kegg lcl|cit:102614215 1 371 + 371 Gaps:19 100.00 362 75.69 0.0 cathepsin B-like
blastp_kegg lcl|rcu:RCOM_1341910 21 369 + 349 Gaps:5 94.15 376 75.71 0.0 cathepsin B putative (EC:3.4.22.1)
blastp_kegg lcl|tcc:TCM_004987 22 369 + 348 Gaps:14 93.04 359 80.84 0.0 Cysteine proteinases superfamily protein
blastp_kegg lcl|vvi:100267480 16 357 + 342 Gaps:14 91.62 358 79.88 0.0 cathepsin B-like
blastp_pdb 3pbh_A 39 353 + 315 Gaps:44 97.48 317 48.87 6e-86 mol:protein length:317 PROCATHEPSIN B
blastp_pdb 2pbh_A 39 353 + 315 Gaps:44 97.48 317 48.87 6e-86 mol:protein length:317 PROCATHEPSIN B
blastp_pdb 1pbh_A 39 353 + 315 Gaps:44 97.48 317 48.87 6e-86 mol:protein length:317 PROCATHEPSIN B
blastp_pdb 1gmy_C 100 360 + 261 Gaps:30 100.00 261 51.72 6e-84 mol:protein length:261 CATHEPSIN B
blastp_pdb 1gmy_B 100 360 + 261 Gaps:30 100.00 261 51.72 6e-84 mol:protein length:261 CATHEPSIN B
blastp_pdb 1gmy_A 100 360 + 261 Gaps:30 100.00 261 51.72 6e-84 mol:protein length:261 CATHEPSIN B
blastp_pdb 3ai8_A 100 353 + 254 Gaps:30 99.22 256 53.15 9e-84 mol:protein length:256 Cathepsin B
blastp_pdb 3ai8_B 100 353 + 254 Gaps:30 99.22 256 53.15 9e-84 mol:protein length:256 Cathepsin B
blastp_pdb 3k9m_B 101 353 + 253 Gaps:30 99.61 254 52.96 6e-83 mol:protein length:254 Cathepsin B
blastp_pdb 3k9m_A 101 353 + 253 Gaps:30 99.61 254 52.96 6e-83 mol:protein length:254 Cathepsin B
blastp_uniprot_sprot sp|Q4R5M2|CATB_MACFA 39 360 + 322 Gaps:44 93.22 339 48.10 2e-85 Cathepsin B OS Macaca fascicularis GN CTSB PE 2 SV 1
blastp_uniprot_sprot sp|Q5R6D1|CATB_PONAB 39 360 + 322 Gaps:44 93.22 339 48.10 3e-85 Cathepsin B OS Pongo abelii GN CTSB PE 2 SV 1
blastp_uniprot_sprot sp|P07858|CATB_HUMAN 39 360 + 322 Gaps:44 93.22 339 47.78 4e-85 Cathepsin B OS Homo sapiens GN CTSB PE 1 SV 3
blastp_uniprot_sprot sp|P00787|CATB_RAT 35 354 + 320 Gaps:48 92.63 339 47.13 9e-83 Cathepsin B OS Rattus norvegicus GN Ctsb PE 1 SV 2
blastp_uniprot_sprot sp|A1E295|CATB_PIG 11 356 + 346 Gaps:59 97.01 335 47.08 3e-80 Cathepsin B OS Sus scrofa GN CTSB PE 1 SV 1
blastp_uniprot_sprot sp|P10605|CATB_MOUSE 35 353 + 319 Gaps:58 92.33 339 46.01 3e-79 Cathepsin B OS Mus musculus GN Ctsb PE 1 SV 2
blastp_uniprot_sprot sp|P43233|CATB_CHICK 10 360 + 351 Gaps:52 98.53 340 43.58 8e-77 Cathepsin B OS Gallus gallus GN CTSB PE 2 SV 1
blastp_uniprot_sprot sp|P25792|CYSP_SCHMA 8 349 + 342 Gaps:43 99.12 340 41.54 1e-76 Cathepsin B-like cysteine proteinase OS Schistosoma mansoni PE 2 SV 1
blastp_uniprot_sprot sp|P43509|CPR5_CAEEL 74 351 + 278 Gaps:40 81.98 344 47.87 5e-75 Cathepsin B-like cysteine proteinase 5 OS Caenorhabditis elegans GN cpr-5 PE 2 SV 1
blastp_uniprot_sprot sp|P43157|CYSP_SCHJA 1 353 + 353 Gaps:53 100.00 342 41.81 2e-74 Cathepsin B-like cysteine proteinase OS Schistosoma japonicum GN CATB PE 2 SV 1

17 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 28 371 344 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 8 19 12 SIGNAL_PEPTIDE_H_REGION none Hydrophobic region of a signal peptide. none
Phobius 1 27 27 SIGNAL_PEPTIDE none Signal peptide region none
PANTHER 40 364 325 PTHR12411:SF16 none none IPR015643
SMART 101 350 250 SM00645 none Papain family cysteine protease IPR000668
PANTHER 40 364 325 PTHR12411 none none IPR013128
Pfam 41 83 43 PF08127 none Peptidase family C1 propeptide IPR012599
Pfam 137 349 213 PF00112 none Papain family cysteine protease IPR000668
SUPERFAMILY 50 351 302 SSF54001 none none none
ProSitePatterns 296 306 11 PS00639 none Eukaryotic thiol (cysteine) proteases histidine active site. IPR025660
Phobius 20 27 8 SIGNAL_PEPTIDE_C_REGION none C-terminal region of a signal peptide. none
PRINTS 314 320 7 PR00705 none Papain cysteine protease (C1) family signature IPR000668
PRINTS 137 152 16 PR00705 none Papain cysteine protease (C1) family signature IPR000668
PRINTS 298 308 11 PR00705 none Papain cysteine protease (C1) family signature IPR000668
Gene3D 94 359 266 G3DSA:3.90.70.10 none none none
Phobius 1 7 7 SIGNAL_PEPTIDE_N_REGION none N-terminal region of a signal peptide. none
ProSitePatterns 137 148 12 PS00139 none Eukaryotic thiol (cysteine) proteases cysteine active site. IPR000169

4 Localization

Analysis Start End Length
TMHMM 7 26 19
SignalP_GRAM_NEGATIVE 1 22 21
SignalP_GRAM_POSITIVE 1 27 26
SignalP_EUK 1 27 26

0 Qtllist

0 Targeting