GO Term : GO:0004843 ubiquitin-specific protease activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin.

0 Cross References

1 Ontology

Name
GO

9 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0004843 ubiquitin-specific protease activity Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin.
GO:0036459 ubiquitinyl hydrolase activity Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.
GO:0008234 cysteine-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0008233 peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0070011 peptidase activity, acting on L-amino acid peptides Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.
GO:0019783 ubiquitin-like protein-specific protease activity Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin or ubiquitin-like proteins (e.g. APG8, ISG15, NEDD8, SUMO), or between the small protein and a larger protein to which it has been conjugated.

6 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0018860.2 Quercus robur 100.0 egn (M=1) K11858 - ubiquitin carboxyl-terminal hydrolase 48 [EC:3.1.2.15]   EC:3.4.19.12 validated
Qrob_P0548670.2 Quercus robur 100.0 egn (M=1) K05610 - ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]   EC:3.4.19.12 validated
Qrob_P0589090.2 Quercus robur 100.0 egn (M=1) PTHR24006:SF360 - UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 4 (PTHR24006:SF360)   EC:3.4.19.12 validated
Qrob_P0619050.2 Quercus robur 85.1 egn (M=1) K12655 - OTU domain-containing protein 5 [EC:3.1.2.15]   EC:3.4.19.12 validated
Qrob_P0742030.2 Quercus robur 100.0 egn (M=1) K05609 - ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]   EC:3.4.19.12 validated
Qrob_P0761730.2 Quercus robur 81.1 egn (M=1) KOG0944//KOG1863//KOG1865//KOG1867//KOG1868//KOG1870//KOG1873//KOG2026 - Ubiquitin-specific protease UBP14 [Posttranslational modification protein turnover chaperones]. // Ubiquitin carboxyl-terminal hydrolase [Posttranslational modification protein turnover chaperones]. // Ubiquitin carboxyl-terminal hydrolase [Posttranslational modification protein turnover chaperones]. // Ubiquitin-specific protease [Posttranslational modification protein turnover chaperones]. // Ubiquitin C-terminal hydrolase [Posttranslational modification protein turnover chaperones]. // Ubiquitin C-terminal hydrolase [Posttranslational modification protein turnover chaperones]. // Ubiquitin-specific protease [Posttranslational modification protein turnover chaperones]. // Spindle pole body protein - Sad1p [Cytoskeleton].   EC:3.4.19.12 validated

13 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0019783 GO:0004843
is_a GO:0036459 GO:0004843
is_a GO:0008233 GO:0004843
is_a GO:0003824 GO:0004843
is_a GO:0070011 GO:0004843
is_a GO:0008234 GO:0004843
is_a GO:0003674 GO:0004843
is_a GO:0016787 GO:0004843
is_a GO:0004843 GO:0061578
is_a GO:0004843 GO:1904265
is_a GO:0004843 GO:1904454
is_a GO:0004843 GO:1904455
is_a GO:0004843 GO:1990380

8 Synonyms

Name Type
ubiquitin hydrolase activity synonym
UBP synonym
UCH2 synonym
deubiquitinase activity synonym
deubiquitinating enzyme synonym
deubiquitylase synonym
ubiquitin C-terminal hydrolase activity synonym
deubiquitinase synonym