GO Term : GO:0004722 protein serine/threonine phosphatase activity GO
Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
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0 Cross References

1 Ontology

Name
GO

8 Parents

Identifier Name Description
GO:0016791 phosphatase activity Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0004722 protein serine/threonine phosphatase activity Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
GO:0016788 hydrolase activity, acting on ester bonds Catalysis of the hydrolysis of any ester bond.
GO:0004721 phosphoprotein phosphatase activity Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.
GO:0042578 phosphoric ester hydrolase activity Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

59 Protein

Protein Identifier
Organism . Name 		Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0010000.2 Quercus robur 99.0 egn (M=1) KOG0614//KOG0698//KOG0699//KOG0700//KOG1113 - cGMP-dependent protein kinase [Signal transduction mechanisms]. // Serine/threonine protein phosphatase [Signal transduction mechanisms]. // Serine/threonine protein phosphatase [Signal transduction mechanisms]. // Protein phosphatase 2C/pyruvate dehydrogenase (lipoamide) phosphatase [Signal transduction mechanisms]. // cAMP-dependent protein kinase types I and II regulatory subunit [Signal transduction mechanisms].     validated
Qrob_P0049200.2 Quercus robur 100.0 egn (M=3) PTHR13832//PTHR13832:SF246 - PROTEIN PHOSPHATASE 2C // SUBFAMILY NOT NAMED   EC:3.1.3.16 validated
Qrob_P0049210.2 Quercus robur 100.0 egn (M=3) PTHR13832//PTHR13832:SF246 - PROTEIN PHOSPHATASE 2C // SUBFAMILY NOT NAMED   EC:3.1.3.16 validated
Qrob_P0062690.2 Quercus robur     (M=3) PTHR13832//PTHR13832:SF269 - PROTEIN PHOSPHATASE 2C // SUBFAMILY NOT NAMED Qrob_P0093620.1 EC:3.1.3.16 manual_v1
Qrob_P0076820.2 Quercus robur 0.0 egn (M=4) PTHR13832:SF228 - PROTEIN PHOSPHATASE 2C 36-RELATED (PTHR13832:SF228)   EC:3.1.3.16 validated
Qrob_P0083080.2 Quercus robur 100.0 egn (M=3) PTHR13832//PTHR13832:SF259 - PROTEIN PHOSPHATASE 2C // SUBFAMILY NOT NAMED   EC:3.1.3.16 validated
Qrob_P0089990.2 Quercus robur 96.1 egn (M=1) K17499 - protein phosphatase 1G [EC:3.1.3.16]   EC:3.1.3.16 validated
Qrob_P0121980.2 Quercus robur 100.0 egn (M=6) K14803 - protein phosphatase 2C homolog 2/3 [EC:3.1.3.16]   EC:3.1.3.16 validated
Qrob_P0125050.2 Quercus robur 100.0 egn (M=1) KOG0192//KOG0618//KOG0697//KOG0698//KOG0699//KOG0700//KOG1323 - Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs [Signal transduction mechanisms]. // Serine/threonine phosphatase 2C containing leucine-rich repeats similar to SCN circadian oscillatory protein (SCOP) [Signal transduction mechanisms]. // Protein phosphatase 1B (formerly 2C) [Signal transduction mechanisms]. // Serine/threonine protein phosphatase [Signal transduction mechanisms]. // Serine/threonine protein phosphatase [Signal transduction mechanisms]. // Protein phosphatase 2C/pyruvate dehydrogenase (lipoamide) phosphatase [Signal transduction mechanisms]. // Serine/threonine phosphatase [Signal transduction mechanisms].   EC:3.1.3.16 validated
Qrob_P0137430.2 Quercus robur 100.0 egn (M=2) PTHR13832//PTHR13832:SF241 - PROTEIN PHOSPHATASE 2C // SUBFAMILY NOT NAMED (PTHR13832:SF241)   EC:3.1.3.16 validated
Qrob_P0145260.2 Quercus robur 0.0 egn (M=4) PTHR13832:SF228 - PROTEIN PHOSPHATASE 2C 36-RELATED (PTHR13832:SF228)   EC:3.1.3.16 validated
Qrob_P0154320.2 Quercus robur 100.0 egn (M=2) PTHR13832//PTHR13832:SF198 - PROTEIN PHOSPHATASE 2C // SUBFAMILY NOT NAMED   EC:3.1.3.16 validated
Qrob_P0199030.2 Quercus robur 100.0 egn (M=4) PTHR13832:SF117 - PREDICTED PROTEIN (FRAGMENT)   EC:3.1.3.16 validated
Qrob_P0200210.2 Quercus robur 100.0 egn (M=1) KOG0697//KOG0698//KOG0700 - Protein phosphatase 1B (formerly 2C) [Signal transduction mechanisms]. // Serine/threonine protein phosphatase [Signal transduction mechanisms]. // Protein phosphatase 2C/pyruvate dehydrogenase (lipoamide) phosphatase [Signal transduction mechanisms].   EC:3.1.3.16 validated
Qrob_P0201570.2 Quercus robur     (M=7) K14497 - protein phosphatase 2C [EC:3.1.3.16] Qrob_P0957280.1 EC:3.1.3.16 manual_v1
Qrob_P0210730.2 Quercus robur 100.0 egn (M=1) KOG0618//KOG0698 - Serine/threonine phosphatase 2C containing leucine-rich repeats similar to SCN circadian oscillatory protein (SCOP) [Signal transduction mechanisms]. // Serine/threonine protein phosphatase [Signal transduction mechanisms].   EC:3.1.3.16 validated
Qrob_P0216840.2 Quercus robur 100.0 egn (M=2) PTHR13832:SF165 - PREDICTED PROTEIN   EC:3.1.3.16 validated
Qrob_P0248460.2 Quercus robur 0.0 egn (M=6) K14803 - protein phosphatase 2C homolog 2/3 [EC:3.1.3.16]   EC:3.1.3.16 validated
Qrob_P0251550.2 Quercus robur 82.0 egn (M=6) K14803 - protein phosphatase 2C homolog 2/3 [EC:3.1.3.16]   EC:3.1.3.16 validated
Qrob_P0260740.2 Quercus robur 0.0 egn (M=3) K01102 - pyruvate dehydrogenase phosphatase [EC:3.1.3.43]   EC:3.1.3.16 validated
Qrob_P0271930.2 Quercus robur 97.0 egn (M=2) PTHR13832:SF223 - PROTEIN PHOSPHATASE 2C 76-RELATED (PTHR13832:SF223)   EC:3.1.3.16 validated
Qrob_P0274410.2 Quercus robur     (M=7) K14497 - protein phosphatase 2C [EC:3.1.3.16] Qrob_P0358200.1 EC:3.1.3.16 manual_v1
Qrob_P0279250.2 Quercus robur 97.1 egn (M=3) K01090 - protein phosphatase [EC:3.1.3.16]   EC:3.1.3.16 validated
Qrob_P0279260.2 Quercus robur 100.0 egn (M=3) K01090 - protein phosphatase [EC:3.1.3.16]   EC:3.1.3.16 validated
Qrob_P0283220.2 Quercus robur 100.0 egn (M=3) K01102 - pyruvate dehydrogenase phosphatase [EC:3.1.3.43]   EC:3.1.3.16 validated
Qrob_P0284130.2 Quercus robur 100.0 egn (M=5) PTHR13832:SF193 - PUTATIVE UNCHARACTERIZED PROTEIN   EC:3.1.3.16 validated
Qrob_P0289660.2 Quercus robur 100.0 egn (M=1) PTHR13832:SF239 - PROTEIN PHOSPHATASE 2C 68-RELATED (PTHR13832:SF239)   EC:3.1.3.16 validated
Qrob_P0321570.2 Quercus robur 100.0 egn (M=2) PTHR13832:SF223 - PROTEIN PHOSPHATASE 2C 76-RELATED (PTHR13832:SF223)   EC:3.1.3.16 validated
Qrob_P0337980.2 Quercus robur 83.2 egn (M=4) PTHR13832:SF25 - PROTEIN PHOSPHATASE, PLANT   EC:3.1.3.16 validated
Qrob_P0337990.2 Quercus robur 100.0 egn (M=4) PTHR13832:SF25 - PROTEIN PHOSPHATASE, PLANT   EC:3.1.3.16 validated

13 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0004721 GO:0004722
is_a GO:0003674 GO:0004722
is_a GO:0042578 GO:0004722
is_a GO:0016787 GO:0004722
is_a GO:0016788 GO:0004722
is_a GO:0003824 GO:0004722
is_a GO:0016791 GO:0004722
is_a GO:0004722 GO:0004723
is_a GO:0004722 GO:0004724
is_a GO:0004722 GO:0008420
is_a GO:0004722 GO:0009400
is_a GO:0004722 GO:0017018
is_a GO:0004722 GO:0033192

41 Synonyms

Name Type
calcineurin synonym
GO:0008600 alt_id
GO:0015071 alt_id
GO:0000163 alt_id
GO:0008598 alt_id
serine/threonine specific protein phosphatase activity synonym
GO:0000158 alt_id
protein phosphatase type 4, intrinsic catalyst activity synonym
protein phosphatase X synonym
GO:0030360 alt_id
GO:0030361 alt_id
GO:0030357 alt_id
GO:0030358 alt_id
3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase synonym
Aspergillus awamori acid protein phosphatase synonym
BCKDH phosphatase synonym
branched-chain alpha-keto acid dehydrogenase phosphatase synonym
casein phosphatase synonym
HMG-CoA reductase phosphatase synonym
phosphatase 2A synonym
phosphatase 2B synonym
phosphatase C-II synonym
phosphatase H-II synonym
phosphatase I synonym
phosphatase IB synonym
phosphatase III synonym
phosphatase II synonym
phosphatase SP synonym
phosphatase IV synonym
phosphospectrin phosphatase synonym