GO Term : GO:0004190 aspartic-type endopeptidase activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.

0 Cross References

1 Ontology

Name
GO

8 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0004190 aspartic-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
GO:0008233 peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GO:0004175 endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0070011 peptidase activity, acting on L-amino acid peptides Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.
GO:0070001 aspartic-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.

83 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0039690.2 Quercus robur 100.0 egn (M=1) PTHR13683:SF250 - ASPARTYL PROTEASE-LIKE PROTEIN (PTHR13683:SF250)   EC:3.4.23.12 validated
Qrob_P0045490.2 Quercus robur 100.0 egn (M=2) PTHR13683:SF224 - ASPARTYL PROTEASE FAMILY PROTEIN-RELATED (PTHR13683:SF224)   EC:3.4.23.12 validated
Qrob_P0111190.2 Quercus robur     (M=2) PTHR13683//PTHR13683:SF225 - ASPARTYL PROTEASES // SUBFAMILY NOT NAMED (PTHR13683:SF225) Qrob_P0004740.1 EC:3.4.23.12 manual_v1
Qrob_P0124340.2 Quercus robur 0.0 egn (M=17) PTHR13683:SF223 - ASPARTYL PROTEASE FAMILY PROTEIN (PTHR13683:SF223)   EC:3.4.23.12 validated
Qrob_P0126240.2 Quercus robur 0.0 egn (M=17) PTHR13683:SF223 - ASPARTYL PROTEASE FAMILY PROTEIN (PTHR13683:SF223)   EC:3.4.23.12 validated
Qrob_P0152340.2 Quercus robur 0.0 egn (M=17) PTHR13683:SF223 - ASPARTYL PROTEASE FAMILY PROTEIN (PTHR13683:SF223)   EC:3.4.23.12 validated
Qrob_P0153210.2 Quercus robur 0.0 egn (M=1) KOG0444//KOG0472//KOG0531//KOG0532//KOG0617//KOG0618//KOG2443//KOG4194//KOG4237//KOG4658 - Cytoskeletal regulator Flightless-I (contains leucine-rich and gelsolin repeats) [Cytoskeleton]. // Leucine-rich repeat protein [Function unknown]. // Protein phosphatase 1 regulatory subunit and related proteins [Signal transduction mechanisms]. // Leucine-rich repeat (LRR) protein contains calponin homology domain [Cytoskeleton]. // Ras suppressor protein (contains leucine-rich repeats) [Signal transduction mechanisms]. // Serine/threonine phosphatase 2C containing leucine-rich repeats similar to SCN circadian oscillatory protein (SCOP) [Signal transduction mechanisms]. // Uncharacterized conserved protein [Function unknown]. // Membrane glycoprotein LIG-1 [Signal transduction mechanisms]. // Extracellular matrix protein slit contains leucine-rich and EGF-like repeats [Extracellular structures Signal transduction mechanisms]. // Apoptotic ATPase [Signal transduction mechanisms].     validated
Qrob_P0153230.2 Quercus robur 95.2 egn (M=1) K09598 - signal peptide peptidase-like 3 [EC:3.4.23.-]     validated
Qrob_P0177000.2 Quercus robur 0.0 egn (M=17) PTHR13683:SF223 - ASPARTYL PROTEASE FAMILY PROTEIN (PTHR13683:SF223)   EC:3.4.23.12 validated
Qrob_P0181970.2 Quercus robur 60.1 egn (M=4) 3.4.23.40 - Phytepsin.   EC:3.4.23.40 validated
Qrob_P0183470.2 Quercus robur 100.0 egn (M=3) PTHR13683//PTHR13683:SF257 - ASPARTYL PROTEASES // SUBFAMILY NOT NAMED   EC:3.4.23.12 validated
Qrob_P0184080.2 Quercus robur 100.0 egn (M=3) PTHR13683//PTHR13683:SF248 - ASPARTYL PROTEASES // SUBFAMILY NOT NAMED (PTHR13683:SF248)   EC:3.4.23.12 validated
Qrob_P0200050.2 Quercus robur 100.0 egn (M=2) PTHR13683:SF224 - ASPARTYL PROTEASE FAMILY PROTEIN-RELATED (PTHR13683:SF224)   EC:3.4.23.12 validated
Qrob_P0215160.2 Quercus robur 85.0 egn (M=3) PTHR13683//PTHR13683:SF257 - ASPARTYL PROTEASES // SUBFAMILY NOT NAMED   EC:3.4.23.12 validated
Qrob_P0264950.2 Quercus robur 83.3 egn (M=1) K09595 - minor histocompatibility antigen H13 [EC:3.4.23.-]     validated
Qrob_P0272050.2 Quercus robur 69.2 egn (M=5) PTHR13683:SF246 - ASPARTYL PROTEASE FAMILY PROTEIN (PTHR13683:SF246)   EC:3.4.23.12 validated
Qrob_P0272060.2 Quercus robur 100.0 egn (M=5) PTHR13683:SF246 - ASPARTYL PROTEASE FAMILY PROTEIN (PTHR13683:SF246)   EC:3.4.23.12 validated
Qrob_P0283050.2 Quercus robur 100.0 egn (M=4) PTHR13683//PTHR13683:SF229 - ASPARTYL PROTEASES // SUBFAMILY NOT NAMED   EC:3.4.23.12 validated
Qrob_P0283070.2 Quercus robur 9.0 egn (M=4) PTHR13683//PTHR13683:SF229 - ASPARTYL PROTEASES // SUBFAMILY NOT NAMED   EC:3.4.23.12 validated
Qrob_P0283100.2 Quercus robur 100.0 egn (M=4) PTHR13683//PTHR13683:SF229 - ASPARTYL PROTEASES // SUBFAMILY NOT NAMED   EC:3.4.23.12 validated
Qrob_P0283110.2 Quercus robur 100.0 egn (M=4) PTHR13683//PTHR13683:SF229 - ASPARTYL PROTEASES // SUBFAMILY NOT NAMED   EC:3.4.23.12 validated
Qrob_P0283370.2 Quercus robur 0.0 egn (M=3) 3.4.23.1 - Pepsin A.   EC:3.4.23.1 validated
Qrob_P0283380.2 Quercus robur     (M=17) PTHR13683:SF232 - ASPARTYL PROTEASE FAMILY PROTEIN (PTHR13683:SF232) Qrob_P0593890.1 EC:3.4.23.12 manual_v1
Qrob_P0283430.2 Quercus robur 0.0 egn (M=17) PTHR13683:SF232 - ASPARTYL PROTEASE FAMILY PROTEIN (PTHR13683:SF232)     validated
Qrob_P0283450.2 Quercus robur 0.0 egn (M=17) PTHR13683:SF232 - ASPARTYL PROTEASE FAMILY PROTEIN (PTHR13683:SF232)     validated
Qrob_P0283460.2 Quercus robur 0.0 egn (M=17) PTHR13683:SF232 - ASPARTYL PROTEASE FAMILY PROTEIN (PTHR13683:SF232)   EC:3.4.23.12 validated
Qrob_P0283470.2 Quercus robur 0.0 egn (M=3) 3.4.23.1 - Pepsin A.   EC:3.4.23.1 validated
Qrob_P0283480.2 Quercus robur 0.0 egn (M=17) PTHR13683:SF232 - ASPARTYL PROTEASE FAMILY PROTEIN (PTHR13683:SF232)   EC:3.4.23.12 validated
Qrob_P0283490.2 Quercus robur 100.0 egn (M=17) PTHR13683:SF232 - ASPARTYL PROTEASE FAMILY PROTEIN (PTHR13683:SF232)   EC:3.4.23.12 validated
Qrob_P0283500.2 Quercus robur 84.0 egn (M=17) PTHR13683:SF232 - ASPARTYL PROTEASE FAMILY PROTEIN (PTHR13683:SF232)   EC:3.4.23.12 validated

9 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0070001 GO:0004190
is_a GO:0004175 GO:0004190
is_a GO:0008233 GO:0004190
is_a GO:0070011 GO:0004190
is_a GO:0003674 GO:0004190
is_a GO:0016787 GO:0004190
is_a GO:0003824 GO:0004190
is_a GO:0004190 GO:0042500
is_a GO:0004190 GO:1902944

5 Synonyms

Name Type
aspartate protease activity synonym
aspartic endopeptidase activity synonym
carboxyl protease activity synonym
aspartic protease activity synonym
aspartyl protease activity synonym