6 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:0016491 | oxidoreductase activity | Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. |
| GO:0003824 | catalytic activity | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
| GO:0004146 | dihydrofolate reductase activity | Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+. |
| GO:0003674 | molecular_function | Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. |
| GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor | Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP. |
| GO:0016645 | oxidoreductase activity, acting on the CH-NH group of donors | Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. |
1 Protein
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0539130.2 | Quercus robur | 45.1 | egn | (M=1) 2.1.1.45 - Thymidylate synthase. | EC:1.5.1.3, EC:2.1.1.45 | validated |
5 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| is_a | GO:0016646 | GO:0004146 |
| is_a | GO:0003824 | GO:0004146 |
| is_a | GO:0016491 | GO:0004146 |
| is_a | GO:0003674 | GO:0004146 |
| is_a | GO:0016645 | GO:0004146 |
13 Synonyms
| Name | Type |
|---|---|
| pteridine reductase:dihydrofolate reductase activity | synonym |
| tetrahydrofolate dehydrogenase activity | synonym |
| folic reductase activity | synonym |
| NADPH-dihydrofolate reductase activity | synonym |
| dihydrofolic reductase activity | synonym |
| folic acid reductase activity | synonym |
| dihydrofolate reduction | synonym |
| dihydrofolic acid reductase activity | synonym |
| dihydrofolate reductase:thymidylate synthase activity | synonym |
| DHFR | synonym |
| 7,8-dihydrofolate reductase activity | synonym |
| 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase activity | synonym |
| thymidylate synthetase-dihydrofolate reductase activity | synonym |
