GO Term : GO:0004707 MAP kinase activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.

0 Cross References

1 Ontology

Name
GO

13 Parents

Identifier Name Description
GO:0004672 protein kinase activity Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016301 kinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0016773 phosphotransferase activity, alcohol group as acceptor Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).
GO:0004674 protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0016772 transferase activity, transferring phosphorus-containing groups Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GO:0004871 signal transducer activity Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
GO:0004707 MAP kinase activity Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0005057 receptor signaling protein activity Conveys a signal from an upstream receptor or intracellular signal transducer, converting the signal into a form where it can ultimately trigger a change in the state or activity of a cell.
GO:0060089 molecular transducer activity The molecular function that accepts an input of one form and creates an output of a different form.
GO:0004702 receptor signaling protein serine/threonine kinase activity Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

6 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0296210.2 Quercus robur 98.3 egn (M=1) PTHR24055:SF7 - MITOGEN-ACTIVATED PROTEIN KINASE 3   EC:2.7.11.24 validated
Qrob_P0388950.2 Quercus robur 100.0 egn (M=6) K04371 - extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]   EC:2.7.11.24 validated
Qrob_P0402300.2 Quercus robur 100.0 egn (M=6) K04371 - extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]   EC:2.7.11.24 validated
Qrob_P0454230.2 Quercus robur 100.0 egn (M=1) PTHR24055:SF158 - MITOGEN-ACTIVATED PROTEIN KINASE 20 (PTHR24055:SF158)   EC:2.7.11.24 validated
Qrob_P0503830.2 Quercus robur 100.0 egn (M=6) K04371 - extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]   EC:2.7.11.24 validated
Qrob_P0656900.2 Quercus robur 100.0 egn (M=1) PTHR24055//PTHR24055:SF157 - MITOGEN-ACTIVATED PROTEIN KINASE // SUBFAMILY NOT NAMED   EC:2.7.11.24 validated

18 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0004707 GO:0004705
is_a GO:0004702 GO:0004707
is_a GO:0060089 GO:0004707
is_a GO:0004871 GO:0004707
is_a GO:0003674 GO:0004707
is_a GO:0016740 GO:0004707
is_a GO:0005057 GO:0004707
is_a GO:0004672 GO:0004707
is_a GO:0016772 GO:0004707
is_a GO:0003824 GO:0004707
is_a GO:0004674 GO:0004707
is_a GO:0016773 GO:0004707
is_a GO:0016301 GO:0004707
is_a GO:0004707 GO:0016909
is_a GO:0004707 GO:0038067
is_a GO:0004707 GO:0038071
is_a GO:0004707 GO:0038075
is_a GO:0004707 GO:0038079

34 Synonyms

Name Type
ATP:protein phosphotransferase (MAPKK-activated) activity synonym
Dp38 synonym
p42mapk synonym
p44mpk synonym
PMK-1 synonym
PMK-2 synonym
p38 synonym
p38-2 synonym
p38delta synonym
p42 mitogen-activated protein kinase activity synonym
STK26 synonym
GO:0008338 alt_id
GO:0008339 alt_id
GO:0016908 alt_id
PMK-3 synonym
pp42 synonym
pp44mapk synonym
SAPK2 synonym
MAP kinase 1 activity synonym
LeMPK3 synonym
MAP-2 kinase activity synonym
MAP kinase 2 activity synonym
ERK1 synonym
ERK synonym
extracellular signal-regulated kinase activity synonym
ERK2 synonym
MP kinase activity synonym
mitogen-activated protein kinase activity synonym
myelin basic protein kinase activity synonym
Mpk2 synonym