Protein : Qrob_P0447850.2 Q. robur
Protein Identifier  ? Qrob_P0447850.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=9) K10878 - meiotic recombination protein SPO11 Code Enzyme  EC:5.99.1.3
Gene Prediction Quality  validated Protein length 

Sequence

Length: 297  
Kegg Orthology  K10878
Paste the following link
Lists
This Protein isn't in any lists. Upload a list.

Sequence Feature Displayer

Protein Sequence Displayer

J Browse Displayer

0 Synonyms

6 GO Terms

Identifier Name Description
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0005524 ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0005694 chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
GO:0006259 DNA metabolic process Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
GO:0000737 DNA catabolic process, endonucleolytic The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.

33 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|crb:CARUB_v10013943mg 1 290 + 290 Gaps:66 93.44 381 58.43 3e-138 hypothetical protein
blastp_kegg lcl|vvi:100256655 1 291 + 291 Gaps:65 98.61 361 63.20 1e-131 meiotic recombination protein SPO11-1-like
blastp_kegg lcl|mdm:103448311 1 296 + 296 Gaps:69 100.00 365 59.18 1e-131 meiotic recombination protein SPO11-1
blastp_kegg lcl|cam:101504128 1 296 + 296 Gaps:72 100.00 354 57.34 5e-130 meiotic recombination protein SPO11-1-like
blastp_kegg lcl|pxb:103941907 1 296 + 296 Gaps:70 100.00 366 58.47 1e-129 meiotic recombination protein SPO11-1-like
blastp_kegg lcl|pxb:103965437 1 296 + 296 Gaps:70 100.00 366 58.47 1e-129 meiotic recombination protein SPO11-1-like
blastp_kegg lcl|cit:102612459 1 291 + 291 Gaps:67 98.08 365 55.87 6e-122 meiotic recombination protein SPO11-1-like
blastp_kegg lcl|tcc:TCM_030659 1 283 + 283 Gaps:45 66.12 484 62.50 6e-121 Spo11/DNA topoisomerase VI
blastp_kegg lcl|bdi:100836198 1 296 + 296 Gaps:69 95.30 383 51.51 1e-117 meiotic recombination protein SPO11-1-like
blastp_kegg lcl|aly:ARALYDRAFT_672143 1 294 + 294 Gaps:65 99.17 362 52.65 9e-114 hypothetical protein
blastp_pdb 2zbk_G 136 296 + 161 Gaps:16 45.50 389 34.46 5e-23 mol:protein length:389 Type II DNA topoisomerase VI subunit A
blastp_pdb 2zbk_E 136 296 + 161 Gaps:16 45.50 389 34.46 5e-23 mol:protein length:389 Type II DNA topoisomerase VI subunit A
blastp_pdb 2zbk_C 136 296 + 161 Gaps:16 45.50 389 34.46 5e-23 mol:protein length:389 Type II DNA topoisomerase VI subunit A
blastp_pdb 2zbk_A 136 296 + 161 Gaps:16 45.50 389 34.46 5e-23 mol:protein length:389 Type II DNA topoisomerase VI subunit A
blastp_pdb 1d3y_B 137 291 + 155 Gaps:13 53.82 301 31.48 3e-18 mol:protein length:301 DNA TOPOISOMERASE VI A SUBUNIT
blastp_pdb 1d3y_A 137 291 + 155 Gaps:13 53.82 301 31.48 3e-18 mol:protein length:301 DNA TOPOISOMERASE VI A SUBUNIT
blastp_pdb 2q2e_A 126 291 + 166 Gaps:21 47.97 369 22.60 4e-10 mol:protein length:369 Type II DNA topoisomerase VI subunit A
blastp_uniprot_sprot sp|Q9M4A2|SPO11_ARATH 1 294 + 294 Gaps:65 99.17 362 51.53 4e-113 Meiotic recombination protein SPO11-1 OS Arabidopsis thaliana GN SPO11-1 PE 1 SV 1
blastp_uniprot_sprot sp|Q9Y5K1|SPO11_HUMAN 73 296 + 224 Gaps:67 72.98 396 30.10 2e-40 Meiotic recombination protein SPO11 OS Homo sapiens GN SPO11 PE 2 SV 1
blastp_uniprot_sprot sp|Q9LZ03|TOP6A_ARATH 71 291 + 221 Gaps:66 66.74 427 30.88 6e-39 DNA topoisomerase 6 subunit A OS Arabidopsis thaliana GN TOP6A PE 1 SV 1
blastp_uniprot_sprot sp|A2XFC1|TOP6A_ORYSI 58 291 + 234 Gaps:72 69.23 442 30.39 2e-36 DNA topoisomerase 6 subunit A OS Oryza sativa subsp. indica GN TOP6A PE 2 SV 2
blastp_uniprot_sprot sp|Q9WTK8|SPO11_MOUSE 136 296 + 161 Gaps:11 42.93 396 36.47 4e-34 Meiotic recombination protein SPO11 OS Mus musculus GN Spo11 PE 2 SV 2
blastp_uniprot_sprot sp|Q22236|SPO11_CAEEL 75 287 + 213 Gaps:57 63.53 425 27.04 2e-27 Meiotic recombination protein spo-11 OS Caenorhabditis elegans GN spo-11 PE 3 SV 1
blastp_uniprot_sprot sp|Q9YE67|TOP6A_AERPE 136 296 + 161 Gaps:19 45.76 389 33.71 2e-24 Type 2 DNA topoisomerase 6 subunit A OS Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) GN top6A PE 3 SV 2
blastp_uniprot_sprot sp|A2BLE8|TOP6A_HYPBU 136 296 + 161 Gaps:20 45.74 387 33.90 6e-23 Type 2 DNA topoisomerase 6 subunit A OS Hyperthermus butylicus (strain DSM 5456 / JCM 9403) GN top6A PE 3 SV 1
blastp_uniprot_sprot sp|O05208|TOP6A_SULSH 136 296 + 161 Gaps:16 45.50 389 34.46 2e-22 Type 2 DNA topoisomerase 6 subunit A OS Sulfolobus shibatae GN top6A PE 1 SV 1
blastp_uniprot_sprot sp|Q971T1|TOP6A_SULTO 136 296 + 161 Gaps:20 45.74 387 32.77 3e-21 Type 2 DNA topoisomerase 6 subunit A OS Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) GN top6A PE 3 SV 1
rpsblast_cdd gnl|CDD|173774 137 280 + 144 Gaps:12 93.75 160 47.33 8e-43 cd00223 TOPRIM_TopoIIB_SPO TOPRIM_TopoIIB_SPO: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in the type IIB family of DNA topoisomerases and Spo11. This subgroup contains proteins similar to Sulfolobus shibatae topoisomerase VI (TopoVI) and Saccharomyces cerevisiae meiotic recombination factor: Spo11. Type II DNA topoisomerases catalyze the ATP-dependent transport of one DNA duplex through another in the process generating transient double strand breaks via covalent attachments to both DNA strands at the 5' positions. TopoVI enzymes are heterotetramers found in archaea and plants. Spo11 plays a role in generating the double strand breaks that initiate homologous recombination during meiosis. S. shibatae TopoVI relaxes both positive and negative supercoils and in addition has a strong decatenase activity. The TOPRIM domain has two conserved motifs one of which centers at a conserved glutamate and the other one at two conserved aspartates (DxD. For topoisomerases the conserved glutamate is believed to act as a general base in strand joining and as a general acid in strand cleavage. The DXD motif may co-ordinate Mg2+ a cofactor required for full catalytic function.
rpsblast_cdd gnl|CDD|31883 6 290 + 285 Gaps:79 98.31 356 26.29 4e-33 COG1697 COG1697 DNA topoisomerase VI subunit A [DNA replication recombination and repair].
rpsblast_cdd gnl|CDD|179833 137 293 + 157 Gaps:16 44.41 367 32.52 2e-30 PRK04342 PRK04342 DNA topoisomerase VI subunit A Provisional.

8 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 13 296 284 PTHR10848:SF3 none none none
Pfam 72 136 65 PF04406 none Type IIB DNA topoisomerase IPR013049
PRINTS 98 109 12 PR01550 none DNA topoisomerase VI subunit A family signature IPR002815
PRINTS 112 129 18 PR01550 none DNA topoisomerase VI subunit A family signature IPR002815
Gene3D 137 292 156 G3DSA:3.40.1360.10 none none none
SUPERFAMILY 73 292 220 SSF56726 none none IPR002815
PANTHER 13 296 284 PTHR10848 none none IPR002815
Gene3D 10 136 127 G3DSA:1.10.10.10 none none IPR011991

0 Localization

8 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran2_2014_nLBD*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,25 0 35,55 lod 2,5951 6
Bourran2_2014_nP*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,19 0 31,97 lod 2,8472 6
Bourran2_2014_nPriLBD_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,36 0 30,43 lod 2,5806 5,1
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nPriBD_3P Qrob_Chr11 11 v_11486_194 s_1AT3E_2335 5,54 0,4 20,6 lod 2,6345 5,9

0 Targeting