Protein : Qrob_P0260970.2 Q. robur
Protein Identifier  ? Qrob_P0260970.2 Organism . Name  Quercus robur
Score  99.0 Score Type  egn
Protein Description  (M=1) PTHR10848:SF0 - MEIOTIC RECOMBINATION PROTEIN SPO11 Code Enzyme  EC:5.99.1.3
Gene Prediction Quality  validated Protein length 

Sequence

Length: 425  
Kegg Orthology  K10878
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0 Synonyms

8 GO Terms

Identifier Name Description
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0005524 ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
GO:0006265 DNA topological change The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
GO:0005694 chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
GO:0006259 DNA metabolic process Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
GO:0000737 DNA catabolic process, endonucleolytic The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.

33 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|cmo:103489716 1 424 + 424 Gaps:4 100.00 420 88.81 0.0 DNA topoisomerase 6 subunit A
blastp_kegg lcl|csv:101222473 1 424 + 424 Gaps:4 100.00 420 89.52 0.0 DNA topoisomerase 6 subunit A-like
blastp_kegg lcl|cam:101513787 1 424 + 424 Gaps:7 100.00 417 87.05 0.0 DNA topoisomerase 6 subunit A-like
blastp_kegg lcl|gmx:100782577 1 424 + 424 Gaps:5 100.00 419 86.16 0.0 DNA topoisomerase 6 subunit A-like
blastp_kegg lcl|cic:CICLE_v10011761mg 1 424 + 424 Gaps:11 100.00 435 83.22 0.0 hypothetical protein
blastp_kegg lcl|cit:102617495 1 424 + 424 Gaps:11 100.00 435 83.22 0.0 DNA topoisomerase 6 subunit A-like
blastp_kegg lcl|vvi:100260201 1 424 + 424 Gaps:4 100.00 420 83.33 0.0 DNA topoisomerase 6 subunit A-like
blastp_kegg lcl|brp:103847420 1 424 + 424 Gaps:13 100.00 429 83.22 0.0 DNA topoisomerase 6 subunit A
blastp_kegg lcl|gmx:100778158 1 424 + 424 Gaps:7 100.00 417 86.09 0.0 DNA topoisomerase 6 subunit A-like
blastp_kegg lcl|pop:POPTR_0006s13490g 1 424 + 424 Gaps:3 100.00 423 84.87 0.0 brassinosteroid insensitive 5 family protein
blastp_pdb 2zbk_G 85 424 + 340 Gaps:27 93.83 389 30.41 3e-54 mol:protein length:389 Type II DNA topoisomerase VI subunit A
blastp_pdb 2zbk_E 85 424 + 340 Gaps:27 93.83 389 30.41 3e-54 mol:protein length:389 Type II DNA topoisomerase VI subunit A
blastp_pdb 2zbk_C 85 424 + 340 Gaps:27 93.83 389 30.41 3e-54 mol:protein length:389 Type II DNA topoisomerase VI subunit A
blastp_pdb 2zbk_A 85 424 + 340 Gaps:27 93.83 389 30.41 3e-54 mol:protein length:389 Type II DNA topoisomerase VI subunit A
blastp_pdb 1d3y_B 143 424 + 282 Gaps:16 96.35 301 35.17 3e-48 mol:protein length:301 DNA TOPOISOMERASE VI A SUBUNIT
blastp_pdb 1d3y_A 143 424 + 282 Gaps:16 96.35 301 35.17 3e-48 mol:protein length:301 DNA TOPOISOMERASE VI A SUBUNIT
blastp_pdb 2q2e_A 85 420 + 336 Gaps:27 94.04 369 29.97 8e-39 mol:protein length:369 Type II DNA topoisomerase VI subunit A
blastp_uniprot_sprot sp|Q9LZ03|TOP6A_ARATH 18 424 + 407 Gaps:7 96.96 427 84.06 0.0 DNA topoisomerase 6 subunit A OS Arabidopsis thaliana GN TOP6A PE 1 SV 1
blastp_uniprot_sprot sp|A2XFC1|TOP6A_ORYSI 7 424 + 418 Gaps:10 95.48 442 68.96 0.0 DNA topoisomerase 6 subunit A OS Oryza sativa subsp. indica GN TOP6A PE 2 SV 2
blastp_uniprot_sprot sp|Q9Y5K1|SPO11_HUMAN 78 424 + 347 Gaps:5 88.38 396 36.00 9e-77 Meiotic recombination protein SPO11 OS Homo sapiens GN SPO11 PE 2 SV 1
blastp_uniprot_sprot sp|Q9WTK8|SPO11_MOUSE 78 424 + 347 Gaps:5 88.38 396 36.29 5e-76 Meiotic recombination protein SPO11 OS Mus musculus GN Spo11 PE 2 SV 2
blastp_uniprot_sprot sp|Q9M4A2|SPO11_ARATH 145 421 + 277 Gaps:1 76.80 362 41.73 8e-70 Meiotic recombination protein SPO11-1 OS Arabidopsis thaliana GN SPO11-1 PE 1 SV 1
blastp_uniprot_sprot sp|Q9YE67|TOP6A_AERPE 93 424 + 332 Gaps:24 91.52 389 33.15 7e-66 Type 2 DNA topoisomerase 6 subunit A OS Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) GN top6A PE 3 SV 2
blastp_uniprot_sprot sp|Q9M4A1|SPO12_ARATH 52 424 + 373 Gaps:25 96.61 383 35.14 7e-60 Meiotic recombination protein SPO11-2 OS Arabidopsis thaliana GN SPO11-2 PE 1 SV 1
blastp_uniprot_sprot sp|A2BLE8|TOP6A_HYPBU 88 424 + 337 Gaps:25 93.02 387 31.39 3e-57 Type 2 DNA topoisomerase 6 subunit A OS Hyperthermus butylicus (strain DSM 5456 / JCM 9403) GN top6A PE 3 SV 1
blastp_uniprot_sprot sp|O05208|TOP6A_SULSH 85 424 + 340 Gaps:27 93.83 389 30.41 9e-54 Type 2 DNA topoisomerase 6 subunit A OS Sulfolobus shibatae GN top6A PE 1 SV 1
blastp_uniprot_sprot sp|Q971T1|TOP6A_SULTO 102 424 + 323 Gaps:25 89.41 387 30.64 2e-51 Type 2 DNA topoisomerase 6 subunit A OS Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) GN top6A PE 3 SV 1
rpsblast_cdd gnl|CDD|179833 79 424 + 346 Gaps:14 97.00 367 34.55 7e-78 PRK04342 PRK04342 DNA topoisomerase VI subunit A Provisional.
rpsblast_cdd gnl|CDD|31883 78 418 + 341 Gaps:8 96.35 356 38.19 3e-72 COG1697 COG1697 DNA topoisomerase VI subunit A [DNA replication recombination and repair].
rpsblast_cdd gnl|CDD|177691 43 424 + 382 Gaps:35 99.22 384 34.91 1e-57 PLN00060 PLN00060 meiotic recombination protein SPO11-2 Provisional.

17 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PRINTS 223 241 19 PR01552 none DNA topoisomerase VI subunit A (TOP6A) signature IPR004085
PRINTS 279 299 21 PR01552 none DNA topoisomerase VI subunit A (TOP6A) signature IPR004085
PRINTS 170 187 18 PR01552 none DNA topoisomerase VI subunit A (TOP6A) signature IPR004085
PRINTS 104 124 21 PR01552 none DNA topoisomerase VI subunit A (TOP6A) signature IPR004085
PRINTS 395 418 24 PR01552 none DNA topoisomerase VI subunit A (TOP6A) signature IPR004085
PANTHER 49 424 376 PTHR10848 none none IPR002815
PANTHER 49 424 376 PTHR10848:SF0 none none none
Pfam 133 200 68 PF04406 none Type IIB DNA topoisomerase IPR013049
Gene3D 203 424 222 G3DSA:3.40.1360.10 none none none
PRINTS 176 193 18 PR01550 none DNA topoisomerase VI subunit A family signature IPR002815
PRINTS 305 321 17 PR01550 none DNA topoisomerase VI subunit A family signature IPR002815
PRINTS 249 266 18 PR01550 none DNA topoisomerase VI subunit A family signature IPR002815
PRINTS 194 209 16 PR01550 none DNA topoisomerase VI subunit A family signature IPR002815
PRINTS 162 173 12 PR01550 none DNA topoisomerase VI subunit A family signature IPR002815
PRINTS 273 294 22 PR01550 none DNA topoisomerase VI subunit A family signature IPR002815
Gene3D 66 201 136 G3DSA:1.10.10.10 none none IPR011991
SUPERFAMILY 137 424 288 SSF56726 none none IPR002815

0 Localization

6 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nEpis*_A4 Qrob_Chr07 7 v_12400_446 s_1BPEBU_1211 6,93 0 15,13 lod 4,7411 11
Bourran2_2014_nLBD_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 37,41 9,8 50,1 lod 1,9524 4,1
Bourran2_2014_nPriBD_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,51 3,36 51,86 lod 1,6747 3,9
Bourran2_2014_nSecLBD_A4 Qrob_Chr07 7 v_8327_222 s_1A4WGY_363 16,04 0 44,69 lod 2,6373 6,5
Bourran2_2014_vEpiBC_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 37,55 14,41 50,01 lod 1,7882 4,8
Champenoux_2015_nEpis_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,53 25,47 27,72 lod 4.4 8.9

0 Targeting