GO Term : GO:0050797 thymidylate synthase (FAD) activity GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+.

0 Cross References

1 Ontology

Name
GO

7 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0008168 methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0016741 transferase activity, transferring one-carbon groups Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor).
GO:0042083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate.
GO:0050797 thymidylate synthase (FAD) activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+.

0 Protein

6 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0042083 GO:0050797
is_a GO:0016741 GO:0050797
is_a GO:0016740 GO:0050797
is_a GO:0008168 GO:0050797
is_a GO:0003824 GO:0050797
is_a GO:0003674 GO:0050797

5 Synonyms

Name Type
ThyX activity synonym
Thy1 activity synonym
5,10-methylenetetrahydrofolate,FADH2:dUMP C-methyltransferase activity synonym
flavin dependent thymidylate synthase activity synonym
FDTS activity synonym